Inhibitors of type 2 vascular endothelial growth factor receptors


Ontology type: sgo:Patent     


Patent Info

DATE

2010-12-28T00:00

AUTHORS

Yan Chen , Elena Getmanova , Martin C. Wright , Alan S. Harris , Ai Ching Lim , Jochem Gokemeijer , Lin Sun , Michael Wittekind

ABSTRACT

The present disclosure relates to novel vascular endothelial growth factor receptor (VEGFR)-binding polypeptides and methods for using these polypeptides to inhibit biological activities mediated by vascular endothelial growth factors (VEGFs). The present disclosure also provides various improvements relating to single domain binding polypeptides.

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/2581", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "name": "Yan Chen", 
        "type": "Person"
      }, 
      {
        "name": "Elena Getmanova", 
        "type": "Person"
      }, 
      {
        "name": "Martin C. Wright", 
        "type": "Person"
      }, 
      {
        "name": "Alan S. Harris", 
        "type": "Person"
      }, 
      {
        "name": "Ai Ching Lim", 
        "type": "Person"
      }, 
      {
        "name": "Jochem Gokemeijer", 
        "type": "Person"
      }, 
      {
        "name": "Lin Sun", 
        "type": "Person"
      }, 
      {
        "name": "Michael Wittekind", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/0166-0934(92)90167-c", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002167277"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0166-0934(92)90167-c", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002167277"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0169-409x(03)00108-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002304749"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0169-409x(03)00108-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002304749"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gr.10.4.398", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004988472"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nbt1197-1222", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005347530", 
          "https://doi.org/10.1038/nbt1197-1222"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.93.20.10703", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006297008"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jps.20125", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006420175"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jmbi.1997.1147", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006519571"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/pro.5560050922", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009749344"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jim.2004.04.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010058491"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1634/stemcells.19-1-24", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010682619"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.061028198", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010810181"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0300-9084(93)90111-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010873310"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0300-9084(93)90111-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010873310"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0022-2836(94)90013-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011026493"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-2836(03)00082-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011679163"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35070613", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011729333", 
          "https://doi.org/10.1038/35070613"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35070613", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011729333", 
          "https://doi.org/10.1038/35070613"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/protein/gzi050", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015364359"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/protein/gzi050", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015364359"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0168-9525(98)01486-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015644059"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jmbi.1998.2238", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016951656"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nbt0697-553", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017819354", 
          "https://doi.org/10.1038/nbt0697-553"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrc778", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017974354", 
          "https://doi.org/10.1038/nrc778"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrc778", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017974354", 
          "https://doi.org/10.1038/nrc778"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/363446a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018109154", 
          "https://doi.org/10.1038/363446a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0168-9525(99)01706-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019337675"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0092-8674(92)90600-h", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019412470"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.270.20.12250", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019686524"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nbt0897-772", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021771430", 
          "https://doi.org/10.1038/nbt0897-772"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/352624a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021945431", 
          "https://doi.org/10.1038/352624a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1074-5521(02)00187-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022722774"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1074-5521(02)00187-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022722774"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1367-5931(99)80042-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024172134"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.0906-6705.2004.00240.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024771867"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/373311a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026631071", 
          "https://doi.org/10.1038/373311a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jmbi.1994.1312", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027372492"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0167-7799(99)01398-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027867143"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0168-9525(96)60040-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028136085"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/protein/gzg093", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029390453"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1083/jcb.133.2.431", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029639815"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.91.14.6423", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031242001"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jmbi.1994.1174", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035474871"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jmr.567", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035792343"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1749-6632.2003.tb03223.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036057833"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1749-6632.2003.tb03223.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036057833"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.leu.2402831", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038120105", 
          "https://doi.org/10.1038/sj.leu.2402831"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.leu.2402831", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038120105", 
          "https://doi.org/10.1038/sj.leu.2402831"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.272.10.6159", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040045011"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1074-5521(02)00098-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040337988"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.271.7.3877", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040649335"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0169-409x(00)00134-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040688819"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0014-5793(97)01026-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041413209"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jmbi.1995.0246", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042770788"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jmr.300070103", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042893802"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jmr.300070103", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042893802"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jmbi.1998.1616", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043519718"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jmbi.1998.1616", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043519718"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/protein/15.12.1015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044054385"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0378-1119(94)90802-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044144266"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0378-1119(94)90802-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044144266"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0378-1119(95)00441-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046468934"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/rheumatology/41.10.1133", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046636306"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m307742200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047310782"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/gut.52.9.1347", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047776861"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0969-2126(00)00034-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047864117"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.iy.06.040188.002121", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048554893"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1083/jcb.141.1.241", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048980408"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/360692a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050511159", 
          "https://doi.org/10.1038/360692a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0968-0004(91)90009-k", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051032279"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jmbi.1994.1272", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051053766"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1389-0352(01)00021-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051079897"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jmbi.1997.1148", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051907409"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gad.10.12.1543", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052472643"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jmbi.2000.4053", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052869337"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/373303a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053068417", 
          "https://doi.org/10.1038/373303a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-2836(84)71582-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1054589671"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00122a025", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055161737"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi010916y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055193973"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi010916y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055193973"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi9526286", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055211232"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi9526286", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055211232"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi952629y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055211233"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi952629y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055211233"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/protein/6.7.745", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059980907"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/protein/8.6.601", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059981249"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/protein/8.8.823", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059981272"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1096920", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062449567"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1279805", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062471450"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jb.175.7.1910-1918.1993", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062722506"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2010-12-28T00:00", 
    "description": "

The present disclosure relates to novel vascular endothelial growth factor receptor (VEGFR)-binding polypeptides and methods for using these polypeptides to inhibit biological activities mediated by vascular endothelial growth factors (VEGFs). The present disclosure also provides various improvements relating to single domain binding polypeptides.

", "id": "sg:patent.US-7858739-B2", "keywords": [ "inhibitor", "vascular endothelial growth factor receptor", "disclosure", "polypeptide", "method", "biological activity", "Vascular Endothelial Growth Factor A", "improvement", "single domain" ], "name": "Inhibitors of type 2 vascular endothelial growth factor receptors", "recipient": [ { "id": "https://www.grid.ac/institutes/grid.419971.3", "type": "Organization" } ], "sameAs": [ "https://app.dimensions.ai/details/patent/US-7858739-B2" ], "sdDataset": "patents", "sdDatePublished": "2019-04-18T10:06", "sdLicense": "https://scigraph.springernature.com/explorer/license/", "sdPublisher": { "name": "Springer Nature - SN SciGraph project", "type": "Organization" }, "sdSource": "s3://com-uberresearch-data-patents-target-20190320-rc/data/sn-export/402f166718b70575fb5d4ffe01f064d1/0000100128-0000352499/json_export_00148.jsonl", "type": "Patent" } ]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/patent.US-7858739-B2'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/patent.US-7858739-B2'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/patent.US-7858739-B2'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/patent.US-7858739-B2'


 

This table displays all metadata directly associated to this object as RDF triples.

298 TRIPLES      15 PREDICATES      99 URIs      17 LITERALS      2 BLANK NODES

Subject Predicate Object
1 sg:patent.US-7858739-B2 schema:about anzsrc-for:2581
2 schema:author N9fb60c84ad79427a96da8d998cc0f64f
3 schema:citation sg:pub.10.1038/35070613
4 sg:pub.10.1038/352624a0
5 sg:pub.10.1038/360692a0
6 sg:pub.10.1038/363446a0
7 sg:pub.10.1038/373303a0
8 sg:pub.10.1038/373311a0
9 sg:pub.10.1038/nbt0697-553
10 sg:pub.10.1038/nbt0897-772
11 sg:pub.10.1038/nbt1197-1222
12 sg:pub.10.1038/nrc778
13 sg:pub.10.1038/sj.leu.2402831
14 https://doi.org/10.1002/jmr.300070103
15 https://doi.org/10.1002/jmr.567
16 https://doi.org/10.1002/jps.20125
17 https://doi.org/10.1002/pro.5560050922
18 https://doi.org/10.1006/jmbi.1994.1174
19 https://doi.org/10.1006/jmbi.1994.1272
20 https://doi.org/10.1006/jmbi.1994.1312
21 https://doi.org/10.1006/jmbi.1995.0246
22 https://doi.org/10.1006/jmbi.1997.1147
23 https://doi.org/10.1006/jmbi.1997.1148
24 https://doi.org/10.1006/jmbi.1998.1616
25 https://doi.org/10.1006/jmbi.1998.2238
26 https://doi.org/10.1006/jmbi.2000.4053
27 https://doi.org/10.1016/0022-2836(94)90013-2
28 https://doi.org/10.1016/0092-8674(92)90600-h
29 https://doi.org/10.1016/0166-0934(92)90167-c
30 https://doi.org/10.1016/0168-9525(96)60040-7
31 https://doi.org/10.1016/0300-9084(93)90111-5
32 https://doi.org/10.1016/0378-1119(94)90802-8
33 https://doi.org/10.1016/0378-1119(95)00441-8
34 https://doi.org/10.1016/0968-0004(91)90009-k
35 https://doi.org/10.1016/j.jim.2004.04.008
36 https://doi.org/10.1016/s0014-5793(97)01026-0
37 https://doi.org/10.1016/s0022-2836(03)00082-2
38 https://doi.org/10.1016/s0022-2836(84)71582-8
39 https://doi.org/10.1016/s0167-7799(99)01398-0
40 https://doi.org/10.1016/s0168-9525(98)01486-3
41 https://doi.org/10.1016/s0168-9525(99)01706-0
42 https://doi.org/10.1016/s0169-409x(00)00134-4
43 https://doi.org/10.1016/s0169-409x(03)00108-x
44 https://doi.org/10.1016/s0969-2126(00)00034-4
45 https://doi.org/10.1016/s1074-5521(02)00098-4
46 https://doi.org/10.1016/s1074-5521(02)00187-4
47 https://doi.org/10.1016/s1367-5931(99)80042-8
48 https://doi.org/10.1016/s1389-0352(01)00021-6
49 https://doi.org/10.1021/bi00122a025
50 https://doi.org/10.1021/bi010916y
51 https://doi.org/10.1021/bi9526286
52 https://doi.org/10.1021/bi952629y
53 https://doi.org/10.1073/pnas.061028198
54 https://doi.org/10.1073/pnas.91.14.6423
55 https://doi.org/10.1073/pnas.93.20.10703
56 https://doi.org/10.1074/jbc.270.20.12250
57 https://doi.org/10.1074/jbc.271.7.3877
58 https://doi.org/10.1074/jbc.272.10.6159
59 https://doi.org/10.1074/jbc.m307742200
60 https://doi.org/10.1083/jcb.133.2.431
61 https://doi.org/10.1083/jcb.141.1.241
62 https://doi.org/10.1093/protein/15.12.1015
63 https://doi.org/10.1093/protein/6.7.745
64 https://doi.org/10.1093/protein/8.6.601
65 https://doi.org/10.1093/protein/8.8.823
66 https://doi.org/10.1093/protein/gzg093
67 https://doi.org/10.1093/protein/gzi050
68 https://doi.org/10.1093/rheumatology/41.10.1133
69 https://doi.org/10.1101/gad.10.12.1543
70 https://doi.org/10.1101/gr.10.4.398
71 https://doi.org/10.1111/j.0906-6705.2004.00240.x
72 https://doi.org/10.1111/j.1749-6632.2003.tb03223.x
73 https://doi.org/10.1126/science.1096920
74 https://doi.org/10.1126/science.1279805
75 https://doi.org/10.1128/jb.175.7.1910-1918.1993
76 https://doi.org/10.1136/gut.52.9.1347
77 https://doi.org/10.1146/annurev.iy.06.040188.002121
78 https://doi.org/10.1634/stemcells.19-1-24
79 schema:datePublished 2010-12-28T00:00
80 schema:description <p num="p-0001">The present disclosure relates to novel vascular endothelial growth factor receptor (VEGFR)-binding polypeptides and methods for using these polypeptides to inhibit biological activities mediated by vascular endothelial growth factors (VEGFs). The present disclosure also provides various improvements relating to single domain binding polypeptides.</p>
81 schema:keywords Vascular Endothelial Growth Factor A
82 biological activity
83 disclosure
84 improvement
85 inhibitor
86 method
87 polypeptide
88 single domain
89 vascular endothelial growth factor receptor
90 schema:name Inhibitors of type 2 vascular endothelial growth factor receptors
91 schema:recipient https://www.grid.ac/institutes/grid.419971.3
92 schema:sameAs https://app.dimensions.ai/details/patent/US-7858739-B2
93 schema:sdDatePublished 2019-04-18T10:06
94 schema:sdLicense https://scigraph.springernature.com/explorer/license/
95 schema:sdPublisher N32a70760400b4624b529e8cb6ce2061f
96 sgo:license sg:explorer/license/
97 sgo:sdDataset patents
98 rdf:type sgo:Patent
99 N0712cf0120344de8a25b8c195c3adfbf rdf:first N3dca7d063f11457cbcfaf443b4b26edc
100 rdf:rest Nff6d74b5a5b64cb2b040c40647f417ee
101 N09b637f13eed4b7da55ba57ed89b5741 rdf:first N1225bf72bd0a47db8bd3a756cb742456
102 rdf:rest N7a93f2725a374dae89b8ee134d6ccd49
103 N1225bf72bd0a47db8bd3a756cb742456 schema:name Martin C. Wright
104 rdf:type schema:Person
105 N2d34629b0b064c8f9e7a45dcc54aa42a schema:name Elena Getmanova
106 rdf:type schema:Person
107 N32a70760400b4624b529e8cb6ce2061f schema:name Springer Nature - SN SciGraph project
108 rdf:type schema:Organization
109 N3dca7d063f11457cbcfaf443b4b26edc schema:name Jochem Gokemeijer
110 rdf:type schema:Person
111 N623589e3d2d94e5f9616dae12030bd66 schema:name Michael Wittekind
112 rdf:type schema:Person
113 N6a4968ae329e4dfdafd08af596357baa schema:name Yan Chen
114 rdf:type schema:Person
115 N7a93f2725a374dae89b8ee134d6ccd49 rdf:first N85f7ec22268b460097884e151d541561
116 rdf:rest Nc917043cb3b9484fa4756fcbf674f33b
117 N857531d509394825a7e799ccdd97dcb2 rdf:first N623589e3d2d94e5f9616dae12030bd66
118 rdf:rest rdf:nil
119 N85f7ec22268b460097884e151d541561 schema:name Alan S. Harris
120 rdf:type schema:Person
121 N93371669038144caa6ae77d5728b4465 schema:name Ai Ching Lim
122 rdf:type schema:Person
123 N9fb60c84ad79427a96da8d998cc0f64f rdf:first N6a4968ae329e4dfdafd08af596357baa
124 rdf:rest Nf460ec7562f442d392ed9ade2308a7cb
125 Nc917043cb3b9484fa4756fcbf674f33b rdf:first N93371669038144caa6ae77d5728b4465
126 rdf:rest N0712cf0120344de8a25b8c195c3adfbf
127 Neede18d2a2d44d249a578c03d65264d4 schema:name Lin Sun
128 rdf:type schema:Person
129 Nf460ec7562f442d392ed9ade2308a7cb rdf:first N2d34629b0b064c8f9e7a45dcc54aa42a
130 rdf:rest N09b637f13eed4b7da55ba57ed89b5741
131 Nff6d74b5a5b64cb2b040c40647f417ee rdf:first Neede18d2a2d44d249a578c03d65264d4
132 rdf:rest N857531d509394825a7e799ccdd97dcb2
133 anzsrc-for:2581 schema:inDefinedTermSet anzsrc-for:
134 rdf:type schema:DefinedTerm
135 sg:pub.10.1038/35070613 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011729333
136 https://doi.org/10.1038/35070613
137 rdf:type schema:CreativeWork
138 sg:pub.10.1038/352624a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021945431
139 https://doi.org/10.1038/352624a0
140 rdf:type schema:CreativeWork
141 sg:pub.10.1038/360692a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050511159
142 https://doi.org/10.1038/360692a0
143 rdf:type schema:CreativeWork
144 sg:pub.10.1038/363446a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018109154
145 https://doi.org/10.1038/363446a0
146 rdf:type schema:CreativeWork
147 sg:pub.10.1038/373303a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053068417
148 https://doi.org/10.1038/373303a0
149 rdf:type schema:CreativeWork
150 sg:pub.10.1038/373311a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026631071
151 https://doi.org/10.1038/373311a0
152 rdf:type schema:CreativeWork
153 sg:pub.10.1038/nbt0697-553 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017819354
154 https://doi.org/10.1038/nbt0697-553
155 rdf:type schema:CreativeWork
156 sg:pub.10.1038/nbt0897-772 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021771430
157 https://doi.org/10.1038/nbt0897-772
158 rdf:type schema:CreativeWork
159 sg:pub.10.1038/nbt1197-1222 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005347530
160 https://doi.org/10.1038/nbt1197-1222
161 rdf:type schema:CreativeWork
162 sg:pub.10.1038/nrc778 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017974354
163 https://doi.org/10.1038/nrc778
164 rdf:type schema:CreativeWork
165 sg:pub.10.1038/sj.leu.2402831 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038120105
166 https://doi.org/10.1038/sj.leu.2402831
167 rdf:type schema:CreativeWork
168 https://doi.org/10.1002/jmr.300070103 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042893802
169 rdf:type schema:CreativeWork
170 https://doi.org/10.1002/jmr.567 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035792343
171 rdf:type schema:CreativeWork
172 https://doi.org/10.1002/jps.20125 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006420175
173 rdf:type schema:CreativeWork
174 https://doi.org/10.1002/pro.5560050922 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009749344
175 rdf:type schema:CreativeWork
176 https://doi.org/10.1006/jmbi.1994.1174 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035474871
177 rdf:type schema:CreativeWork
178 https://doi.org/10.1006/jmbi.1994.1272 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051053766
179 rdf:type schema:CreativeWork
180 https://doi.org/10.1006/jmbi.1994.1312 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027372492
181 rdf:type schema:CreativeWork
182 https://doi.org/10.1006/jmbi.1995.0246 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042770788
183 rdf:type schema:CreativeWork
184 https://doi.org/10.1006/jmbi.1997.1147 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006519571
185 rdf:type schema:CreativeWork
186 https://doi.org/10.1006/jmbi.1997.1148 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051907409
187 rdf:type schema:CreativeWork
188 https://doi.org/10.1006/jmbi.1998.1616 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043519718
189 rdf:type schema:CreativeWork
190 https://doi.org/10.1006/jmbi.1998.2238 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016951656
191 rdf:type schema:CreativeWork
192 https://doi.org/10.1006/jmbi.2000.4053 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052869337
193 rdf:type schema:CreativeWork
194 https://doi.org/10.1016/0022-2836(94)90013-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011026493
195 rdf:type schema:CreativeWork
196 https://doi.org/10.1016/0092-8674(92)90600-h schema:sameAs https://app.dimensions.ai/details/publication/pub.1019412470
197 rdf:type schema:CreativeWork
198 https://doi.org/10.1016/0166-0934(92)90167-c schema:sameAs https://app.dimensions.ai/details/publication/pub.1002167277
199 rdf:type schema:CreativeWork
200 https://doi.org/10.1016/0168-9525(96)60040-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028136085
201 rdf:type schema:CreativeWork
202 https://doi.org/10.1016/0300-9084(93)90111-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010873310
203 rdf:type schema:CreativeWork
204 https://doi.org/10.1016/0378-1119(94)90802-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044144266
205 rdf:type schema:CreativeWork
206 https://doi.org/10.1016/0378-1119(95)00441-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046468934
207 rdf:type schema:CreativeWork
208 https://doi.org/10.1016/0968-0004(91)90009-k schema:sameAs https://app.dimensions.ai/details/publication/pub.1051032279
209 rdf:type schema:CreativeWork
210 https://doi.org/10.1016/j.jim.2004.04.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010058491
211 rdf:type schema:CreativeWork
212 https://doi.org/10.1016/s0014-5793(97)01026-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041413209
213 rdf:type schema:CreativeWork
214 https://doi.org/10.1016/s0022-2836(03)00082-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011679163
215 rdf:type schema:CreativeWork
216 https://doi.org/10.1016/s0022-2836(84)71582-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1054589671
217 rdf:type schema:CreativeWork
218 https://doi.org/10.1016/s0167-7799(99)01398-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027867143
219 rdf:type schema:CreativeWork
220 https://doi.org/10.1016/s0168-9525(98)01486-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015644059
221 rdf:type schema:CreativeWork
222 https://doi.org/10.1016/s0168-9525(99)01706-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019337675
223 rdf:type schema:CreativeWork
224 https://doi.org/10.1016/s0169-409x(00)00134-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040688819
225 rdf:type schema:CreativeWork
226 https://doi.org/10.1016/s0169-409x(03)00108-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1002304749
227 rdf:type schema:CreativeWork
228 https://doi.org/10.1016/s0969-2126(00)00034-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047864117
229 rdf:type schema:CreativeWork
230 https://doi.org/10.1016/s1074-5521(02)00098-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040337988
231 rdf:type schema:CreativeWork
232 https://doi.org/10.1016/s1074-5521(02)00187-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022722774
233 rdf:type schema:CreativeWork
234 https://doi.org/10.1016/s1367-5931(99)80042-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024172134
235 rdf:type schema:CreativeWork
236 https://doi.org/10.1016/s1389-0352(01)00021-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051079897
237 rdf:type schema:CreativeWork
238 https://doi.org/10.1021/bi00122a025 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055161737
239 rdf:type schema:CreativeWork
240 https://doi.org/10.1021/bi010916y schema:sameAs https://app.dimensions.ai/details/publication/pub.1055193973
241 rdf:type schema:CreativeWork
242 https://doi.org/10.1021/bi9526286 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055211232
243 rdf:type schema:CreativeWork
244 https://doi.org/10.1021/bi952629y schema:sameAs https://app.dimensions.ai/details/publication/pub.1055211233
245 rdf:type schema:CreativeWork
246 https://doi.org/10.1073/pnas.061028198 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010810181
247 rdf:type schema:CreativeWork
248 https://doi.org/10.1073/pnas.91.14.6423 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031242001
249 rdf:type schema:CreativeWork
250 https://doi.org/10.1073/pnas.93.20.10703 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006297008
251 rdf:type schema:CreativeWork
252 https://doi.org/10.1074/jbc.270.20.12250 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019686524
253 rdf:type schema:CreativeWork
254 https://doi.org/10.1074/jbc.271.7.3877 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040649335
255 rdf:type schema:CreativeWork
256 https://doi.org/10.1074/jbc.272.10.6159 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040045011
257 rdf:type schema:CreativeWork
258 https://doi.org/10.1074/jbc.m307742200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047310782
259 rdf:type schema:CreativeWork
260 https://doi.org/10.1083/jcb.133.2.431 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029639815
261 rdf:type schema:CreativeWork
262 https://doi.org/10.1083/jcb.141.1.241 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048980408
263 rdf:type schema:CreativeWork
264 https://doi.org/10.1093/protein/15.12.1015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044054385
265 rdf:type schema:CreativeWork
266 https://doi.org/10.1093/protein/6.7.745 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059980907
267 rdf:type schema:CreativeWork
268 https://doi.org/10.1093/protein/8.6.601 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059981249
269 rdf:type schema:CreativeWork
270 https://doi.org/10.1093/protein/8.8.823 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059981272
271 rdf:type schema:CreativeWork
272 https://doi.org/10.1093/protein/gzg093 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029390453
273 rdf:type schema:CreativeWork
274 https://doi.org/10.1093/protein/gzi050 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015364359
275 rdf:type schema:CreativeWork
276 https://doi.org/10.1093/rheumatology/41.10.1133 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046636306
277 rdf:type schema:CreativeWork
278 https://doi.org/10.1101/gad.10.12.1543 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052472643
279 rdf:type schema:CreativeWork
280 https://doi.org/10.1101/gr.10.4.398 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004988472
281 rdf:type schema:CreativeWork
282 https://doi.org/10.1111/j.0906-6705.2004.00240.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1024771867
283 rdf:type schema:CreativeWork
284 https://doi.org/10.1111/j.1749-6632.2003.tb03223.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1036057833
285 rdf:type schema:CreativeWork
286 https://doi.org/10.1126/science.1096920 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062449567
287 rdf:type schema:CreativeWork
288 https://doi.org/10.1126/science.1279805 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062471450
289 rdf:type schema:CreativeWork
290 https://doi.org/10.1128/jb.175.7.1910-1918.1993 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062722506
291 rdf:type schema:CreativeWork
292 https://doi.org/10.1136/gut.52.9.1347 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047776861
293 rdf:type schema:CreativeWork
294 https://doi.org/10.1146/annurev.iy.06.040188.002121 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048554893
295 rdf:type schema:CreativeWork
296 https://doi.org/10.1634/stemcells.19-1-24 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010682619
297 rdf:type schema:CreativeWork
298 https://www.grid.ac/institutes/grid.419971.3 schema:Organization
 




Preview window. Press ESC to close (or click here)


...