Control of gene expression


Ontology type: sgo:Patent     


Patent Info

DATE

2010-07-13T00:00

AUTHORS

Michael Wayne Graham , Robert Norman Rice

ABSTRACT

The present invention relates generally to a method of modifying gene expression and to synthetic genes for modifying endogenous gene expression in a cell, tissue or organ of a transgenic organism, in particular a transgenic animal or plant. More particularly, the present invention utilises recombinant DNA technology to post-transciptionally modify or modulate the expression of a target gene in a cell tissue, organ or whole organism, thereby producing novel phenotypes. Novel synthetic genes and genetic constructs which are capable repressing delaying or otherwise reducing the expression of an endogenous gene or a target gene in an organism when introduced thereto are also provided. More... »

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    The present invention relates generally to a method of modifying gene expression and to synthetic genes for modifying endogenous gene expression in a cell, tissue or organ of a transgenic organism, in particular a transgenic animal or plant. More particularly, the present invention utilises recombinant DNA technology to post-transciptionally modify or modulate the expression of a target gene in a cell tissue, organ or whole organism, thereby producing novel phenotypes. Novel synthetic genes and genetic constructs which are capable repressing delaying or otherwise reducing the expression of an endogenous gene or a target gene in an organism when introduced thereto are also provided.

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    368 schema:datePublished 2010-07-13T00:00
    369 schema:description <p num="p-0001">The present invention relates generally to a method of modifying gene expression and to synthetic genes for modifying endogenous gene expression in a cell, tissue or organ of a transgenic organism, in particular a transgenic animal or plant. More particularly, the present invention utilises recombinant DNA technology to post-transciptionally modify or modulate the expression of a target gene in a cell tissue, organ or whole organism, thereby producing novel phenotypes. Novel synthetic genes and genetic constructs which are capable repressing delaying or otherwise reducing the expression of an endogenous gene or a target gene in an organism when introduced thereto are also provided.</p>
    370 schema:keywords Genetically Modified Animal
    371 Genetically Modified Organism
    372 cell
    373 control
    374 endogenous gene
    375 endogenous gene expression
    376 expression
    377 gene expression
    378 genetic construct
    379 invention
    380 method
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    386 synthetic gene
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    388 tissue
    389 schema:name Control of gene expression
    390 schema:recipient https://www.grid.ac/institutes/grid.1016.6
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