Targeting p38 mitogen activated protein kinase (MAPK) cellular signaling pathway; using such as N,N'-bis(3,5-diacetylphenyl)decanediamide tetrakis(amidinohydrazone) tetrahydrochloride


Ontology type: sgo:Patent     


Patent Info

DATE

2010-06-22T00:00

AUTHORS

TRACEY KEVIN J , COHEN PAMELA , BUKRINSKY MICHAEL , SCHMIDTMAYEROVA HELENA

ABSTRACT

There is disclosed a method for treating diseases and disorders involving T cell activation and HIV-infection using the p38 mitogen activated protein kinase (MAPK) signaling pathway as a target for intervention. There is further disclosed a use for guanylhydrazone-substituted compounds to treat diseases and disorders related to T cell activation and HIV-infection. More... »

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