Capillary array and related methods


Ontology type: sgo:Patent     


Patent Info

DATE

2010-06-22T00:00

AUTHORS

Mack J Fulwyler , Joe W Gray

ABSTRACT

The invention provides methods and devices for detecting the presence of one or more target analytes in a sample employing a channel having affixed therein one or more binding partners for each target analyte. Assays are carried out by transporting the sample through the channel to each successive binding partner so that target analyte present in said sample binds to the corresponding binding partner. The sample is then transported beyond the binding partner(s), followed by detection of any target analyte bound to each binding partner. In one embodiment, binding efficiency is increased by the use of segmented transport, wherein a first bolus or bubble of a fluid that is immiscible with the sample precedes the sample during transport and a second bolus or bubble of a fluid that is immiscible with the sample follows the sample. Many configurations are possible for the device of the invention. A preferred device includes: a substrate with a channel formed in its surface, and a cover element that overlies and seals the channel. Binding partner(s) are affixed to the surface of the cover element facing the channel lumen. More... »

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/2428", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "name": "Mack J Fulwyler", 
        "type": "Person"
      }, 
      {
        "name": "Joe W Gray", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/ng1296-457", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010987019", 
          "https://doi.org/10.1038/ng1296-457"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/12640", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014821425", 
          "https://doi.org/10.1038/12640"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/12640", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014821425", 
          "https://doi.org/10.1038/12640"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/7921", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019407436", 
          "https://doi.org/10.1038/7921"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/7921", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019407436", 
          "https://doi.org/10.1038/7921"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cyto.990190105", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020612835"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cyto.990190105", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020612835"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.91.6.2156", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022993456"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/2524", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026409761", 
          "https://doi.org/10.1038/2524"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/2524", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026409761", 
          "https://doi.org/10.1038/2524"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gr.6.7.639", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028833356"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/gcc.2870100403", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038266174"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nm0798-844", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051373741", 
          "https://doi.org/10.1038/nm0798-844"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/22.24.5456", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052392947"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1359641", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062477301"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1990438", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062516646"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.283.5398.57", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062563697"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/ajcp/28.3_ts.311", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1075753472"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2010-06-22T00:00", 
    "description": "

The invention provides methods and devices for detecting the presence of one or more target analytes in a sample employing a channel having affixed therein one or more binding partners for each target analyte. Assays are carried out by transporting the sample through the channel to each successive binding partner so that target analyte present in said sample binds to the corresponding binding partner. The sample is then transported beyond the binding partner(s), followed by detection of any target analyte bound to each binding partner. In one embodiment, binding efficiency is increased by the use of segmented transport, wherein a first bolus or bubble of a fluid that is immiscible with the sample precedes the sample during transport and a second bolus or bubble of a fluid that is immiscible with the sample follows the sample. Many configurations are possible for the device of the invention. A preferred device includes: a substrate with a channel formed in its surface, and a cover element that overlies and seals the channel. Binding partner(s) are affixed to the surface of the cover element facing the channel lumen.

", "id": "sg:patent.US-7741104-B2", "keywords": [ "capillary", "related method", "invention", "method", "Equipment and Supply", "target analytes", "sample", "binding partner", "assay", "embodiment", "efficiency", "transport", "wherein", "bolus", "bubble", "fluid", "configuration", "substrate", "surface", "element", "seal", "lumen" ], "name": "Capillary array and related methods", "recipient": [ { "id": "https://www.grid.ac/institutes/grid.30389.31", "type": "Organization" } ], "sameAs": [ "https://app.dimensions.ai/details/patent/US-7741104-B2" ], "sdDataset": "patents", "sdDatePublished": "2019-04-18T10:05", "sdLicense": "https://scigraph.springernature.com/explorer/license/", "sdPublisher": { "name": "Springer Nature - SN SciGraph project", "type": "Organization" }, "sdSource": "s3://com-uberresearch-data-patents-target-20190320-rc/data/sn-export/402f166718b70575fb5d4ffe01f064d1/0000100128-0000352499/json_export_00076.jsonl", "type": "Patent" } ]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/patent.US-7741104-B2'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/patent.US-7741104-B2'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/patent.US-7741104-B2'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/patent.US-7741104-B2'


 

This table displays all metadata directly associated to this object as RDF triples.

95 TRIPLES      15 PREDICATES      50 URIs      30 LITERALS      2 BLANK NODES

Subject Predicate Object
1 sg:patent.US-7741104-B2 schema:about anzsrc-for:2428
2 schema:author N6902ebcb1b154919a386451c46d8ec4f
3 schema:citation sg:pub.10.1038/12640
4 sg:pub.10.1038/2524
5 sg:pub.10.1038/7921
6 sg:pub.10.1038/ng1296-457
7 sg:pub.10.1038/nm0798-844
8 https://doi.org/10.1002/cyto.990190105
9 https://doi.org/10.1002/gcc.2870100403
10 https://doi.org/10.1073/pnas.91.6.2156
11 https://doi.org/10.1093/ajcp/28.3_ts.311
12 https://doi.org/10.1093/nar/22.24.5456
13 https://doi.org/10.1101/gr.6.7.639
14 https://doi.org/10.1126/science.1359641
15 https://doi.org/10.1126/science.1990438
16 https://doi.org/10.1126/science.283.5398.57
17 schema:datePublished 2010-06-22T00:00
18 schema:description <p num="p-0001">The invention provides methods and devices for detecting the presence of one or more target analytes in a sample employing a channel having affixed therein one or more binding partners for each target analyte. Assays are carried out by transporting the sample through the channel to each successive binding partner so that target analyte present in said sample binds to the corresponding binding partner. The sample is then transported beyond the binding partner(s), followed by detection of any target analyte bound to each binding partner. In one embodiment, binding efficiency is increased by the use of segmented transport, wherein a first bolus or bubble of a fluid that is immiscible with the sample precedes the sample during transport and a second bolus or bubble of a fluid that is immiscible with the sample follows the sample. Many configurations are possible for the device of the invention. A preferred device includes: a substrate with a channel formed in its surface, and a cover element that overlies and seals the channel. Binding partner(s) are affixed to the surface of the cover element facing the channel lumen.</p>
19 schema:keywords Equipment and Supply
20 assay
21 binding partner
22 bolus
23 bubble
24 capillary
25 configuration
26 efficiency
27 element
28 embodiment
29 fluid
30 invention
31 lumen
32 method
33 related method
34 sample
35 seal
36 substrate
37 surface
38 target analytes
39 transport
40 wherein
41 schema:name Capillary array and related methods
42 schema:recipient https://www.grid.ac/institutes/grid.30389.31
43 schema:sameAs https://app.dimensions.ai/details/patent/US-7741104-B2
44 schema:sdDatePublished 2019-04-18T10:05
45 schema:sdLicense https://scigraph.springernature.com/explorer/license/
46 schema:sdPublisher N23ab55bb18ca4e6a80f806908d4e6298
47 sgo:license sg:explorer/license/
48 sgo:sdDataset patents
49 rdf:type sgo:Patent
50 N23ab55bb18ca4e6a80f806908d4e6298 schema:name Springer Nature - SN SciGraph project
51 rdf:type schema:Organization
52 N523b028d7f7c4916800fd1874d8bee96 schema:name Mack J Fulwyler
53 rdf:type schema:Person
54 N53b7c5d2fa174e3cb60319f5488397f8 schema:name Joe W Gray
55 rdf:type schema:Person
56 N6902ebcb1b154919a386451c46d8ec4f rdf:first N523b028d7f7c4916800fd1874d8bee96
57 rdf:rest Nf035f7bc311a4985a72dcc1e09209918
58 Nf035f7bc311a4985a72dcc1e09209918 rdf:first N53b7c5d2fa174e3cb60319f5488397f8
59 rdf:rest rdf:nil
60 anzsrc-for:2428 schema:inDefinedTermSet anzsrc-for:
61 rdf:type schema:DefinedTerm
62 sg:pub.10.1038/12640 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014821425
63 https://doi.org/10.1038/12640
64 rdf:type schema:CreativeWork
65 sg:pub.10.1038/2524 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026409761
66 https://doi.org/10.1038/2524
67 rdf:type schema:CreativeWork
68 sg:pub.10.1038/7921 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019407436
69 https://doi.org/10.1038/7921
70 rdf:type schema:CreativeWork
71 sg:pub.10.1038/ng1296-457 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010987019
72 https://doi.org/10.1038/ng1296-457
73 rdf:type schema:CreativeWork
74 sg:pub.10.1038/nm0798-844 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051373741
75 https://doi.org/10.1038/nm0798-844
76 rdf:type schema:CreativeWork
77 https://doi.org/10.1002/cyto.990190105 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020612835
78 rdf:type schema:CreativeWork
79 https://doi.org/10.1002/gcc.2870100403 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038266174
80 rdf:type schema:CreativeWork
81 https://doi.org/10.1073/pnas.91.6.2156 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022993456
82 rdf:type schema:CreativeWork
83 https://doi.org/10.1093/ajcp/28.3_ts.311 schema:sameAs https://app.dimensions.ai/details/publication/pub.1075753472
84 rdf:type schema:CreativeWork
85 https://doi.org/10.1093/nar/22.24.5456 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052392947
86 rdf:type schema:CreativeWork
87 https://doi.org/10.1101/gr.6.7.639 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028833356
88 rdf:type schema:CreativeWork
89 https://doi.org/10.1126/science.1359641 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062477301
90 rdf:type schema:CreativeWork
91 https://doi.org/10.1126/science.1990438 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062516646
92 rdf:type schema:CreativeWork
93 https://doi.org/10.1126/science.283.5398.57 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062563697
94 rdf:type schema:CreativeWork
95 https://www.grid.ac/institutes/grid.30389.31 schema:Organization
 




Preview window. Press ESC to close (or click here)


...