Rational evolution of cytokines for higher stability, the cytokines and encoding nucleic acid molecules


Ontology type: sgo:Patent     


Patent Info

DATE

2010-01-19T00:00

AUTHORS

Rene Gantier , Manuel Vega , Lila Drittanti , Thierry Guyon

ABSTRACT

Compositions of modified cytokines and uses thereof generated using processes and systems for the high throughput directed evolution of peptides and proteins, particularly cytokines that act in complex biological settings, are provided. Also provided are modified cytokines formulated for oral delivery and uses thereof to treat diseases and conditions mediated by cytokines. More... »

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