Using mass tag complex as tool in monitoring transcriptional patterns of a plurality of biological molecules; diagnosing infection, cell proliferative, ...


Ontology type: sgo:Patent     


Patent Info

DATE

2009-08-04T00:00

AUTHORS

LEVY SHAWN , CAPRIOLI RICHARD M

ABSTRACT

The present invention provides mass tag complexes that permit simultaneously obtaining information of a plurality of biological molecules. The biological molecules may be RNA or protein, and the information includes both level of expression as well as spatial disposition within a cell or tissue. The mass tag comprise a core structure, a target binding structure (e.g., nucleic acid or peptide binding structure), a cleavable linker and a mass tag that exhibits a unique mass spectroscopy signal. More... »

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