Pyrazole compounds useful as protein kinase inhibitors


Ontology type: sgo:Patent     


Patent Info

DATE

2009-05-12T00:00

AUTHORS

BEBBINGTON DAVID , CHARRIER JEAN-DAMIEN , GOLEC JULIAN , MILLER ANDREW , KNEGTEL RONALD

ABSTRACT

This invention describes novel pyrazole compounds of formula IIIa: wherein R1 is T-Ring D, wherein Ring D is a 5-7 membered monocyclic ring or 8-10 membered bicyclic ring selected from aryl, heteroaryl, heterocyclyl or carbocyclyl; Rx, Ry, R2; and R2′ are as described in the specification. The compounds are useful as protein kinase inhibitors, especially as inhibitors of Aurora-2 and GSK-3, for treating diseases such as cancer, diabetes and Alzheimer's disease. More... »

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