Compositions and methods related to modified retroviral vectors for restricted, site specific integration


Ontology type: sgo:Patent     


Patent Info

DATE

N/A

AUTHORS

Paul B. McCray, Jr. , Patrick L. Sinn , Daniel F. Voytas , Junbiao Dai

ABSTRACT

Embodiments of the invention include compositions comprising and methods utilizing a retroviral integrase complex comprising a recombinant integrase having a domain comprising a non-native protein binding site, and a DNA binding protein comprising a DNA binding domain and a peptide binding domain that binds the non-native protein binding site of the recombinant integrase. More... »

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