kits for quantitative determination of differential protein expression and/or modification in different samples; solid phase synthesis


Ontology type: sgo:Patent     


Patent Info

DATE

2008-09-09T00:00

AUTHORS

FISCHER STEVEN M

ABSTRACT

The present invention provides a new and improved method for reducing the complexity of a proteomic sample, and preferably also for allowing identification of proteins in the sample. In one aspect, the invention provides a highly efficient method for identifying proteins in a proteomic sample by characterizing a single N-terminal peptide per protein. In another aspect, the invention provides a method for identifying proteins in a proteomic sample by characterizing a single C-terminal peptide per protein. In another aspect, the present invention provides a method for quantitative determination of differential protein expression and/or modification in different samples. In another aspect, the invention relates to kits useful for conveniently performing a method in accordance with the invention. More... »

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