Methods of identifying substances that interact with JTT-1 protein


Ontology type: sgo:Patent     


Patent Info

DATE

2007-11-13T00:00

AUTHORS

Takuya Tamatani , Katsunari Tezuka

ABSTRACT

Novel cell surface molecules recognized by monoclonal antibodies against a cell surface molecule of lymphocytic cells that play an important role in autoimmune diseases and allergic diseases have been isolated, identified, and analyzed for their functions. The cell surface molecules are expressed specifically in thymocytes, lymphocytes activated by ConA-stimulation, and peripheral blood lymphocytes, and induce cell adhesion. Antibodies against the cell surface molecules significantly ameliorate pathological conditions of autoimmune diseases and allergic diseases. More... »

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