inhibiting SH2 domain binding with a phosphoprotein; to inhibit proliferation of tumor cells; for inhibiting the growth of human breast ...


Ontology type: sgo:Patent     


Patent Info

DATE

2007-06-05T00:00

AUTHORS

BURKE JR TERRENCE R , GAO YANG , YAO ZHU-JUN , YANG DAJUN

ABSTRACT

Disclosed herein are phenylalanine derivative compounds of the following formula W—Y—(AA)n—Z wherein Y is a phenylalanyl radical, AA is an amino acid, n is an integer of 1 to 15, and substituent variables W and Z are as described herein. The compounds can be used to inhibit SH2 binding with phosphoproteins, and to inhibit proliferation of tumor cells. More... »

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