Rho kinase inhibitors


Ontology type: sgo:Patent     


Patent Info

DATE

2007-04-03T00:00

AUTHORS

Naonori Imazaki , Masafumi Kitano , Naohito Ohashi , Kazuki Matsui

ABSTRACT

A compound represented by the formula (1): wherein R1—X— indicates that 1 to 4 R1—X— groups are present which may be the same or different, the ring A is a saturated or unsaturated 5-membered heterocyclic ring,X is a single bond, a group represented by the formula: —N(R3)—, —O— or —S—, or the like.R1 is a hydrogen atom, a halogen atom, a nitro group, a carboxyl group, a substituted or unsubstituted alkyl group, or the like,R2 is a hydrogen atom, a halogen atom, a nitro group, a carboxyl group, a substituted or unsubstituted alkyl group, or the like, andR3 is a hydrogen atom, a substituted or unsubstituted alkyl group, or the like; a prodrug of said compound, or a pharmaceutically acceptable salt of said compound or prodrug is a useful compound as a therapeutic agent for diseases for which Rho kinase is responsible. More... »

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