Methods for modulating expression of exogenous genes in mammalian systems


Ontology type: sgo:Patent     


Patent Info

DATE

2006-05-16T00:00

AUTHORS

Ronald M. Evans , Enrique Saez

ABSTRACT

In accordance with the present invention, there are provided various methods for modulating the expression of an exogenous gene in an isolated cell and in a mammalian subject employing modified ecdysone receptors. Also provided are modified ecdysone receptors, as well as homomeric and heterodimeric receptors containing same, nucleic acids encoding invention modified ecdysone receptors, modified hormone response elements, gene transfer vectors, recombinant cells, and transgenic animals containing nucleic acids encoding invention modified ecdysone receptor. More... »

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