Methods and compositions for effecting homologous recombination


Ontology type: sgo:Patent     


Patent Info

DATE

2005-08-30T00:00

AUTHORS

Marie Dutreix , Jian-Sheng Sun , Elodie Biet , Rosalie Maurisse , Jean-Paul Feugeas

ABSTRACT

This invention concerns a method for effecting directed mutagenesis based on a guided homologous recombination system that comprises (i) a triple helix forming oligonucleotide, (ii) a donor nucleic acid segment, and (iii) an adapter segment comprising an oligonucleotide sequence able to bind at least a portion of said donor nucleic acid through Watson-Crick base pairing. More... »

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