Method of producing undifferentiated hemopoietic stem cells using a stationary phase plug-flow bioreactor


Ontology type: sgo:Patent     


Patent Info

DATE

2005-06-28T00:00

AUTHORS

Shoshana Merchav , Shai Meretzki

ABSTRACT

A method of expanding/maintaining undifferentiated hemopoietic stem cells or progenitor cells by obtaining undifferentiated hemopoietic stem cells or progenitor cells; and either seeding the undifferentiated hemopoietic stem cells or progenitor cells into a stationary phase plug-flow bioreactor in which a three-dimensional stromal cell culture has been pre-established on a substrate in the form of a sheet, the substrate including a non-woven fibrous matrix forming a physiologically acceptable three-dimensional network of fibers, thereby expanding/maintaining undifferentiated hemopoietic stem cells or progenitor cells, or culturing the undifferentiated hemopoietic stem cells or progenitor cells in conditioned medium obtained from such a reactor. More... »

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/2581", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "name": "Shoshana Merchav", 
        "type": "Person"
      }, 
      {
        "name": "Shai Meretzki", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1002/stem.5530100508", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021088326"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/stem.5530100508", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021088326"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0927-7765(94)80040-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037604581"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.gt.3300480", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039691813", 
          "https://doi.org/10.1038/sj.gt.3300480"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.gt.3300480", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039691813", 
          "https://doi.org/10.1038/sj.gt.3300480"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/stem.5530120408", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044117865"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/stem.5530120408", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044117865"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2005-06-28T00:00", 
    "description": "

A method of expanding/maintaining undifferentiated hemopoietic stem cells or progenitor cells by obtaining undifferentiated hemopoietic stem cells or progenitor cells; and either seeding the undifferentiated hemopoietic stem cells or progenitor cells into a stationary phase plug-flow bioreactor in which a three-dimensional stromal cell culture has been pre-established on a substrate in the form of a sheet, the substrate including a non-woven fibrous matrix forming a physiologically acceptable three-dimensional network of fibers, thereby expanding/maintaining undifferentiated hemopoietic stem cells or progenitor cells, or culturing the undifferentiated hemopoietic stem cells or progenitor cells in conditioned medium obtained from such a reactor.

", "id": "sg:patent.US-6911201-B1", "keywords": [ "method", "hemopoietic stem cell", "stationary phase", "stem cell", "stromal cell", "substrate", "sheet", "matrix", "three-dimensional network", "fiber", "culturing", "Conditioned Culture Medium", "reactor" ], "name": "Method of producing undifferentiated hemopoietic stem cells using a stationary phase plug-flow bioreactor", "recipient": [ { "id": "https://www.grid.ac/institutes/grid.6451.6", "type": "Organization" }, { "id": "https://www.grid.ac/institutes/grid.459855.0", "type": "Organization" } ], "sameAs": [ "https://app.dimensions.ai/details/patent/US-6911201-B1" ], "sdDataset": "patents", "sdDatePublished": "2019-04-18T10:28", "sdLicense": "https://scigraph.springernature.com/explorer/license/", "sdPublisher": { "name": "Springer Nature - SN SciGraph project", "type": "Organization" }, "sdSource": "s3://com-uberresearch-data-patents-target-20190320-rc/data/sn-export/402f166718b70575fb5d4ffe01f064d1/0000100128-0000352499/json_export_03157.jsonl", "type": "Patent" } ]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/patent.US-6911201-B1'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/patent.US-6911201-B1'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/patent.US-6911201-B1'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/patent.US-6911201-B1'


 

This table displays all metadata directly associated to this object as RDF triples.

54 TRIPLES      15 PREDICATES      32 URIs      21 LITERALS      2 BLANK NODES

Subject Predicate Object
1 sg:patent.US-6911201-B1 schema:about anzsrc-for:2581
2 schema:author N534959b93d3d4be0be6c5dd441da39a2
3 schema:citation sg:pub.10.1038/sj.gt.3300480
4 https://doi.org/10.1002/stem.5530100508
5 https://doi.org/10.1002/stem.5530120408
6 https://doi.org/10.1016/0927-7765(94)80040-5
7 schema:datePublished 2005-06-28T00:00
8 schema:description <p num="p-0001">A method of expanding/maintaining undifferentiated hemopoietic stem cells or progenitor cells by obtaining undifferentiated hemopoietic stem cells or progenitor cells; and either seeding the undifferentiated hemopoietic stem cells or progenitor cells into a stationary phase plug-flow bioreactor in which a three-dimensional stromal cell culture has been pre-established on a substrate in the form of a sheet, the substrate including a non-woven fibrous matrix forming a physiologically acceptable three-dimensional network of fibers, thereby expanding/maintaining undifferentiated hemopoietic stem cells or progenitor cells, or culturing the undifferentiated hemopoietic stem cells or progenitor cells in conditioned medium obtained from such a reactor.</p>
9 schema:keywords Conditioned Culture Medium
10 culturing
11 fiber
12 hemopoietic stem cell
13 matrix
14 method
15 reactor
16 sheet
17 stationary phase
18 stem cell
19 stromal cell
20 substrate
21 three-dimensional network
22 schema:name Method of producing undifferentiated hemopoietic stem cells using a stationary phase plug-flow bioreactor
23 schema:recipient https://www.grid.ac/institutes/grid.459855.0
24 https://www.grid.ac/institutes/grid.6451.6
25 schema:sameAs https://app.dimensions.ai/details/patent/US-6911201-B1
26 schema:sdDatePublished 2019-04-18T10:28
27 schema:sdLicense https://scigraph.springernature.com/explorer/license/
28 schema:sdPublisher N7e276e8c57f04f459566b0e8d1304cca
29 sgo:license sg:explorer/license/
30 sgo:sdDataset patents
31 rdf:type sgo:Patent
32 N17aeb13b18da47c0967531895226c613 schema:name Shoshana Merchav
33 rdf:type schema:Person
34 N2cf85fd944b24b7da7ffa7fee488d473 schema:name Shai Meretzki
35 rdf:type schema:Person
36 N534959b93d3d4be0be6c5dd441da39a2 rdf:first N17aeb13b18da47c0967531895226c613
37 rdf:rest Nd2293f32b1ac47ac9e2693bc4addc46a
38 N7e276e8c57f04f459566b0e8d1304cca schema:name Springer Nature - SN SciGraph project
39 rdf:type schema:Organization
40 Nd2293f32b1ac47ac9e2693bc4addc46a rdf:first N2cf85fd944b24b7da7ffa7fee488d473
41 rdf:rest rdf:nil
42 anzsrc-for:2581 schema:inDefinedTermSet anzsrc-for:
43 rdf:type schema:DefinedTerm
44 sg:pub.10.1038/sj.gt.3300480 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039691813
45 https://doi.org/10.1038/sj.gt.3300480
46 rdf:type schema:CreativeWork
47 https://doi.org/10.1002/stem.5530100508 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021088326
48 rdf:type schema:CreativeWork
49 https://doi.org/10.1002/stem.5530120408 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044117865
50 rdf:type schema:CreativeWork
51 https://doi.org/10.1016/0927-7765(94)80040-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037604581
52 rdf:type schema:CreativeWork
53 https://www.grid.ac/institutes/grid.459855.0 schema:Organization
54 https://www.grid.ac/institutes/grid.6451.6 schema:Organization
 




Preview window. Press ESC to close (or click here)


...