Methods and compositions for treatment of HIV-1 infection using antiviral compounds in simultaneous or sequential combinations


Ontology type: sgo:Patent     


Patent Info

DATE

2005-03-01T00:00

AUTHORS

JOHNSON M ROSS , LAMBERT DENNIS MICHAEL

ABSTRACT

Novel antiviral combinations for the treatment or prevention of viral infections, in particular, HIV, are disclosed. This new antiviral therapy employs either DP-178 or DP-107, viral fusion inhibitors, in combination with at least one other antiviral therapeutic agent. The combinations of the invention are better than single therapies alone, and in certain cases are synergistic. The use of DP-178 or DP-107 is an ideal therapy to combine with another antiviral, given both the novel mechanism which this therapeutic blocks HIV transmission and the non-toxicity of the therapeutic. More... »

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