Modified Morbillivirus V proteins


Ontology type: sgo:Patent     


Patent Info

DATE

2003-12-16T00:00

AUTHORS

Christopher L. Parks

ABSTRACT

Modified Morbilliviruses having at least one mutation in the region corresponding to amino acids 112-134 of the measles virus V protein are described, wherein one or both of amino acids 113 or 114 is mutated. Such modified Morbilliviruses exhibit reduced repression of gene expression. Additional mutations or deletions in other regions of the genome may be included, including in the carboxy-terminal region. More... »

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