Identification of components of E3 complex involved in ubiquitination of cell cycle regulator proteins, including a class of proteins that ...


Ontology type: sgo:Patent     


Patent Info

DATE

2003-06-03T00:00

AUTHORS

HARPER JEFFREY WADE , ELLEDGE STEPHEN J

ABSTRACT

The present invention provides compositions and methods for gene identification, as well as drug discovery and assessment. In particular, the present invention provides components of an E3 complex involved in ubiquitination of cell cycle regulators and other proteins, as well as members of a class of proteins that directly function in recognition of ubiquitination targets. The present invention also provides sequences of multiple F-box proteins. More... »

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