Nucleic acid encoding a chimeric polypeptide


Ontology type: sgo:Patent     


Patent Info

DATE

2003-05-20T00:00

AUTHORS

Richard F. Selden , Marianne Borowski , Frances P. Gillispie , Carol M. Kinoshita , Douglas A. Treco , Melanie D. Williams

ABSTRACT

A therapeutic method whereby an individual suspected of having an α-galactosidase A deficiency, such as Fabry disease, is treated either with (1) human cells that have been genetically modified to overexpress and secrete human α-gal A, or (2) purified human α-gal A obtained from cultured, genetically modified human cells.

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