Mitogen-activated protein kinase kinase MEK6 and variants thereof


Ontology type: sgo:Patent     


Patent Info

DATE

2000-06-13T00:00

AUTHORS

STEIN BERND , YANG MARIA X H

ABSTRACT

Compositions and methods are provide for potentiating the activity of the mitogen-activated protein kinase p38. In particular the mitogen-activated protein kinase kinase MEK6, and variants thereof that stimulate phosphorylation of p38 are provided. Such compounds may be used, for example, for therapy of diseases associated with the p38 cascade and to identify antibodies and other agents that inhibit or activate signal transduction via p38. More... »

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