Synthetic triple helix-forming compound precursors


Ontology type: sgo:Patent     


Patent Info

DATE

1998-12-01T00:00

AUTHORS

Barry I. Gold

ABSTRACT

The present invention discloses novel monomeric compositions which are substituted quinoline- or quinazoline-based structures capable of hydrogen bonding specifically with interstrand purine-pyrimidine base pairs in a double-stranded Watson-Crick DNA molecule. Furthermore, the novel monomeric compounds of the present invention are capable of being assembled in specific sequences into oligomers capable of binding with sequence specificity to duplex DNA via a triple helix motif. More... »

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