Polypeptide fusions to polypeptides of the beta-trefoil fold structural family


Ontology type: sgo:Patent     


Patent Info

DATE

N/A

AUTHORS

Desmond Mascarenhas , Yang Zhang , Pamela S. Olson , David R. Olsen , Pedro A. Carrillo

ABSTRACT

The invention is directed to the use of IL-1-like fusion polypeptides to increase the solubility and activity of recombinant polypeptides. The invention includes a nucleic acid encoding a fusion polypeptide comprising an interleukin-1-like polypeptide and a polypeptide of interest and the method of using such a nucleic acid to produce recombinant fusion polypeptides. More... »

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