Use of prosaposin and neurotrophic peptides derived therefrom


Ontology type: sgo:Patent     


Patent Info

DATE

1998-02-03T00:00

AUTHORS

O'BRIEN JOHN S , KISHIMOTO YASUO

ABSTRACT

Prosaposin, saposin C and various peptide fragments of saposin C stimulate neurite outgrowth in vitro. In addition, prosaposin and saposin C promote increased myelination ex vivo. Prosaposin is present in large neurons of the brain, including both upper and lower motor neurons.

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