Fusion proteins


Ontology type: sgo:Patent     


Patent Info

DATE

1997-12-23T00:00

AUTHORS

Susan Elizabeth Newton , Berwyn Ewart Clarke

ABSTRACT

A DNA sequence encoding a fusion protein comprising influenza virus HA, at a site of which normally occupied by a natural antigenic epitope thereof a different antigenic epitope is provided, is incorporated in a vector which is capable of expressing the fusion protein when provided in a eucaryotic host. When in the form of a viral vector such as a recombinant vaccinia virus, the vector can be used as a vaccine. Alternatively, the fusion protein expressed by the host can be recovered and provided as a vaccine. More... »

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