Peptides that induce antibodies which neutralize genetically divergent HIV-1 isolates


Ontology type: sgo:Patent     


Patent Info

DATE

N/A

AUTHORS

Hermann Katinger , Florian Ruker , Gottfried Himmler , Thomas Muster , Alexandra Trkola , Martin Purtscher , Georg Maiwald , Franz Steindl

ABSTRACT

This invention refers to peptides binding to antibodies that show neutralizing activity against different strains and clinical isolates of HIV-1 and that inhibit the fusion of cells caused by HIV-1. These peptides are applied with an adjuvant, as recombinant fusion proteins, chemically coupled to carrier molecules, as recombinant chimeric viruses or as recombinant antibodies. More... »

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