Recombinant altered antibodies and methods of making altered antibodies


Ontology type: sgo:Patent     


Patent Info

DATE

1993-07-06T00:00

AUTHORS

Gregory P. Winter

ABSTRACT

An altered antibody is produced by replacing the complementarity determining regions (CDRs) of a variable region of an immunoglobulin (Ig) with the CDRs from an Ig of different specificity, using recombinant DNA techniques. The gene coding sequences for producing the altered antibody may be produced by site-directed mutagenesis using long oligonucleotides. More... »

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