Composition Of Anti-Endo180 Antibodies And Methods Of Use For The Treatment Of Cancer And Fibrotic Diseases


Ontology type: sgo:Patent     


Patent Info

DATE

2014-03-13T00:00

AUTHORS

Elena Feinstein

ABSTRACT

The present invention provides antibodies or antigen-binding fragments thereof that specifically bind the ENDO180 polypeptide and are internalized thereby, to conjugates comprising the molecules, to compositions comprising the antibodies and conjugates and to methods of using the same for delivery of therapeutic agents to cells that express the ENDO180 polypeptide on the surface of the cell for treating cell proliferative diseases or disorders and fibrosis, and for controlling (modulating) tumor progression. More... »

Related SciGraph Publications

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/3103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "name": "Elena Feinstein", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1159/000072654", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012895947"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.gt.3301923", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043735865", 
          "https://doi.org/10.1038/sj.gt.3301923"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.gt.3301923", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043735865", 
          "https://doi.org/10.1038/sj.gt.3301923"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2014-03-13T00:00", 
    "description": "

The present invention provides antibodies or antigen-binding fragments thereof that specifically bind the ENDO180 polypeptide and are internalized thereby, to conjugates comprising the molecules, to compositions comprising the antibodies and conjugates and to methods of using the same for delivery of therapeutic agents to cells that express the ENDO180 polypeptide on the surface of the cell for treating cell proliferative diseases or disorders and fibrosis, and for controlling (modulating) tumor progression.

", "id": "sg:patent.US-20140072552-A1", "keywords": [ "composition", "fibrotic disease", "invention", "antibody", "antigen binding", "polypeptide", "conjugate", "molecule", "method", "delivery", "therapeutic agent", "cell", "surface", "proliferative disease", "disorder", "fibrosis", "tumor progression" ], "name": "COMPOSITION OF ANTI-ENDO180 ANTIBODIES AND METHODS OF USE FOR THE TREATMENT OF CANCER AND FIBROTIC DISEASES", "recipient": [ { "id": "https://www.grid.ac/institutes/grid.488373.3", "type": "Organization" } ], "sameAs": [ "https://app.dimensions.ai/details/patent/US-20140072552-A1" ], "sdDataset": "patents", "sdDatePublished": "2019-04-18T10:12", "sdLicense": "https://scigraph.springernature.com/explorer/license/", "sdPublisher": { "name": "Springer Nature - SN SciGraph project", "type": "Organization" }, "sdSource": "s3://com-uberresearch-data-patents-target-20190320-rc/data/sn-export/402f166718b70575fb5d4ffe01f064d1/0000100128-0000352499/json_export_00745.jsonl", "type": "Patent" } ]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/patent.US-20140072552-A1'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/patent.US-20140072552-A1'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/patent.US-20140072552-A1'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/patent.US-20140072552-A1'


 

This table displays all metadata directly associated to this object as RDF triples.

46 TRIPLES      15 PREDICATES      33 URIs      25 LITERALS      2 BLANK NODES

Subject Predicate Object
1 sg:patent.US-20140072552-A1 schema:about anzsrc-for:3103
2 schema:author N675391731aa14e81bb57483a9a3f4834
3 schema:citation sg:pub.10.1038/sj.gt.3301923
4 https://doi.org/10.1159/000072654
5 schema:datePublished 2014-03-13T00:00
6 schema:description <p id="p-0001" num="0000">The present invention provides antibodies or antigen-binding fragments thereof that specifically bind the ENDO180 polypeptide and are internalized thereby, to conjugates comprising the molecules, to compositions comprising the antibodies and conjugates and to methods of using the same for delivery of therapeutic agents to cells that express the ENDO180 polypeptide on the surface of the cell for treating cell proliferative diseases or disorders and fibrosis, and for controlling (modulating) tumor progression.</p>
7 schema:keywords antibody
8 antigen binding
9 cell
10 composition
11 conjugate
12 delivery
13 disorder
14 fibrosis
15 fibrotic disease
16 invention
17 method
18 molecule
19 polypeptide
20 proliferative disease
21 surface
22 therapeutic agent
23 tumor progression
24 schema:name COMPOSITION OF ANTI-ENDO180 ANTIBODIES AND METHODS OF USE FOR THE TREATMENT OF CANCER AND FIBROTIC DISEASES
25 schema:recipient https://www.grid.ac/institutes/grid.488373.3
26 schema:sameAs https://app.dimensions.ai/details/patent/US-20140072552-A1
27 schema:sdDatePublished 2019-04-18T10:12
28 schema:sdLicense https://scigraph.springernature.com/explorer/license/
29 schema:sdPublisher Nbdf4352abdc14df3a66955a74ff148fc
30 sgo:license sg:explorer/license/
31 sgo:sdDataset patents
32 rdf:type sgo:Patent
33 N675391731aa14e81bb57483a9a3f4834 rdf:first Na414f7e7471240d39f549db58a046c9f
34 rdf:rest rdf:nil
35 Na414f7e7471240d39f549db58a046c9f schema:name Elena Feinstein
36 rdf:type schema:Person
37 Nbdf4352abdc14df3a66955a74ff148fc schema:name Springer Nature - SN SciGraph project
38 rdf:type schema:Organization
39 anzsrc-for:3103 schema:inDefinedTermSet anzsrc-for:
40 rdf:type schema:DefinedTerm
41 sg:pub.10.1038/sj.gt.3301923 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043735865
42 https://doi.org/10.1038/sj.gt.3301923
43 rdf:type schema:CreativeWork
44 https://doi.org/10.1159/000072654 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012895947
45 rdf:type schema:CreativeWork
46 https://www.grid.ac/institutes/grid.488373.3 schema:Organization
 




Preview window. Press ESC to close (or click here)


...