Process for depositing calcium phosphate therapeutic coatings with different release rates and a prosthesis coated via the process


Ontology type: sgo:Patent     


Patent Info

DATE

N/A

AUTHORS

Marisa A. Little , Nader M. Kalkhoran , Arash Aslani , Eric J. Tobin , Jason E. Burns

ABSTRACT

A method of coating a substrate including loading a calcium phosphate substance at a first crystallinity with a therapeutic agent; depositing the loaded calcium phosphate substance at the first crystallinity onto a least a portion of the substance; loading a calcium phosphate substance at a second, lower, crystallinity with a therapeutic agent; and depositing the loaded calcium phosphate substance at the second crystallinity onto the deposited loaded calcium phosphate substance at the first crystallinity to control and sustain a long-term osseointegration response and to control the release rate of the therapeutic substance from the calcium phosphate substance. More... »

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