Methods To Improve Alcohol Tolerance Of Microorganisms


Ontology type: sgo:Patent     


Patent Info

DATE

2010-12-16T00:00

AUTHORS

VILLA-GARCIA MANUEL J , KRAUSE ERIN J , WALKER LARRY P , HENRY SUSAN A

ABSTRACT

The present invention is directed to a method of producing organisms tolerant to alcohol, that includes selecting a microorganism needing tolerance to alcohol and modifying the selected microorganism under conditions effective to overproduce inositol by the microorganism compared to when the microorganism is not modified, with the modified microorganism being tolerant to alcohol. The present invention is also directed to a method of producing alcohol that includes providing a microorganism tolerant to alcohol which is modified to overproduce inositol by the microorganism compared to when the microorganism is not modified. A fermentable feedstock is treated with the modified microorganism under conditions effective to produce the alcohol. The modified microorganism is also able to produce and tolerate alcohol in high osmolarity feedstocks. More... »

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