Alvocidib prodrugs and their use as protein kinase inhibitors


Ontology type: sgo:Patent     


Patent Info

DATE

2022-03-22T00:00

AUTHORS

SIDDIQUI-JAIN ADAM , SAWAYAMA YUSUKE , HIROSE WATARU , BAN HITOSHI

ABSTRACT

Compounds having the following structure (I) or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof, wherein R1, R2 and R3 are as defined herein, and wherein at least one of R1, R2 and R3 is not H, are provided. Pharmaceutical compositions comprising the compounds and methods for use of the compounds for treating diseases associated with overexpression of a cyclin-dependent kinase (CDK) are also provided. More... »

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