Method for evaluating blood coagulation reaction


Ontology type: sgo:Patent     


Patent Info

DATE

2021-08-03T00:00

AUTHORS

SOEDA TETSUHIRO , KITAZAWA TAKEHISA , SHIMA MIDORI

ABSTRACT

Various methods for evaluating hemostatic effect and various blood coagulation initiation reagents were studied to construct a method for evaluating blood coagulation reaction mediated by a substance having an activity of substituting for coagulation factor VIII (FVIII). As a result, it was discovered that by using a coagulation initiation reagent containing activated coagulation factor XI (FXIa) and phospholipids, the effect of a substance having an activity of substituting for coagulation factor VIII (FVIII) on blood coagulation reaction can be evaluated using the amount of thrombin generated in the blood sample as an indicator. More... »

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