Adenosine nucleobase editors and uses thereof


Ontology type: sgo:Patent     


Patent Info

DATE

2018-10-30T00:00

AUTHORS

LIU DAVID R , GAUDELLI NICOLE

ABSTRACT

The disclosure provides adenosine deaminases that are capable of deaminating adenosine in DNA. The disclosure also provides fusion proteins comprising a Cas9 (e.g., a Cas9 nickase) domain and adenosine deaminases that deaminate adenosine in DNA. In some embodiments, the fusion proteins further comprise a nuclear localization sequence (NLS), and/or an inhibitor of base repair, such as, a nuclease dead inosine specific nuclease (dISN). More... »

Related SciGraph Publications

  • 1994-03. Expression of a dominant negative retinoic acid receptor γ in Xenopus embryos leads to partial resistance to retinoic acid in DEVELOPMENT GENES AND EVOLUTION
  • 2016-04-20. Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage in NATURE
  • 2013-01-08. Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy in NATURE REVIEWS NEUROLOGY
  • 2017-07-25. Programmable base editing of zebrafish genome using a modified CRISPR-Cas9 system in NATURE COMMUNICATIONS
  • 2013-02-10. TALENs and ZFNs are associated with different mutation signatures in NATURE METHODS
  • 2012-04-24. Conditional Gene Expression in the Mouse Inner Ear Using Cre-loxP in JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY
  • 2016-10-31. Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells in NATURE METHODS
  • 2017-08-19. Highly efficient and precise base editing in discarded human tripronuclear embryos in PROTEIN & CELL
  • 2014-12-16. GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases in NATURE BIOTECHNOLOGY
  • 2015-04-01. In vivo genome editing using Staphylococcus aureus Cas9 in NATURE
  • 2012-05-16. The landscape of cancer genes and mutational processes in breast cancer in NATURE
  • 2013-02-10. Robust, synergistic regulation of human gene expression using TALE activators in NATURE METHODS
  • 2012-01-05. A transcription activator-like effector toolbox for genome engineering in NATURE PROTOCOLS
  • 2006-11-26. Post-translational enzyme activation in an animal via optimized conditional protein splicing in NATURE CHEMICAL BIOLOGY
  • 2010-12-22. A TALE nuclease architecture for efficient genome editing in NATURE BIOTECHNOLOGY
  • 2014-07-27. Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease in NATURE
  • 2014-02-16. Broad specificity profiling of TALENs results in engineered nucleases with improved DNA-cleavage specificity in NATURE METHODS
  • 2015-06-22. Engineered CRISPR-Cas9 nucleases with altered PAM specificities in NATURE
  • 2015-02-05. Therapeutic genome editing: prospects and challenges in NATURE MEDICINE
  • 2016-10-10. Targeted AID-mediated mutagenesis (TAM) enables efficient genomic diversification in mammalian cells in NATURE METHODS
  • 2017-02-27. Highly efficient RNA-guided base editing in mouse embryos in NATURE BIOTECHNOLOGY
  • 2008. Design and Testing of Zinc Finger Nucleases for Use in Mammalian Cells in CHROMOSOMAL MUTAGENESIS
  • 2017-02-27. Precise base editing in rice, wheat and maize with a Cas9-cytidine deaminase fusion in NATURE BIOTECHNOLOGY
  • 2015-04-01. Long-term and efficient expression of human β-globin gene in a hematopoietic cell line using a new site-specific integrating non-viral system in GENE THERAPY
  • 2012-02-15. RNA-guided genetic silencing systems in bacteria and archaea in NATURE
  • 1999-02. Disentangling the perturbational effects of amino acid substitutions in the DNA-binding domain of p53 in HUMAN GENETICS
  • 2011-11-08. Evaluation of genomic high-throughput sequencing data generated on Illumina HiSeq and Genome Analyzer systems in GENOME BIOLOGY
  • 2014-01-29. DNA interrogation by the CRISPR RNA-guided endonuclease Cas9 in NATURE
  • 2011-03-30. CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III in NATURE
  • 2011-01-12. Shape-based peak identification for ChIP-Seq in BMC BIOINFORMATICS
  • 2014-03-14. Homologous recombination in human embryonic stem cells using CRISPR/Cas9 nickase and a long DNA donor template in PROTEIN & CELL
  • 2013-09-27. Cas9 as a versatile tool for engineering biology in NATURE METHODS
  • 2012-11-21. TALENs: a widely applicable technology for targeted genome editing in NATURE REVIEWS MOLECULAR CELL BIOLOGY
  • 2014-09-28. Programmable RNA recognition and cleavage by CRISPR/Cas9 in NATURE
  • 2015-01-30. DNA methylation age of blood predicts all-cause mortality in later life in GENOME BIOLOGY
  • 2005-02. Intervening Sequences of Regularly Spaced Prokaryotic Repeats Derive from Foreign Genetic Elements in JOURNAL OF MOLECULAR EVOLUTION
  • 2005-04-03. Highly efficient endogenous human gene correction using designed zinc-finger nucleases in NATURE
  • 2012-07-05. Conditional gene manipulation: Cre-ating a new biological era in JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B
  • 2013-06-23. High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells in NATURE BIOTECHNOLOGY
  • 2014-02-16. DNA-guided DNA interference by a prokaryotic Argonaute in NATURE
  • 2012-09-18. Leucine to proline substitution by SNP at position 197 in Caspase-9 gene expression leads to neuroblastoma: a bioinformatics analysis in 3 BIOTECH
  • 2013-01-29. RNA-guided editing of bacterial genomes using CRISPR-Cas systems in NATURE BIOTECHNOLOGY
  • 2010-01-10. APOBEC3 proteins mediate the clearance of foreign DNA from human cells in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2013-01-29. Efficient genome editing in zebrafish using a CRISPR-Cas system in NATURE BIOTECHNOLOGY
  • 2016-11-28. Failure to detect DNA-guided genome editing using Natronobacterium gregoryi Argonaute in NATURE BIOTECHNOLOGY
  • 2013-01-29. Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease in NATURE BIOTECHNOLOGY
  • 2013-06-16. Near-infrared fluorescent proteins for multicolor in vivo imaging in NATURE METHODS
  • 2011-08-07. Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection in NATURE METHODS
  • 2013-02-17. A library of TAL effector nucleases spanning the human genome in NATURE BIOTECHNOLOGY
  • 2013-10-24. Genome engineering using the CRISPR-Cas9 system in NATURE PROTOCOLS
  • 2015-03-23. Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining in NATURE BIOTECHNOLOGY
  • 2015-03-24. Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells in NATURE BIOTECHNOLOGY
  • 2015-07-01. Trans-spliced Cas9 allows cleavage of HBB and CCR5 genes in human cells using compact expression cassettes in SCIENTIFIC REPORTS
  • 2011-08-01. Targeted gene disruption in somatic zebrafish cells using engineered TALENs in NATURE BIOTECHNOLOGY
  • 2016-02-22. Directed evolution of a recombinase that excises the provirus of most HIV-1 primary isolates with high specificity in NATURE BIOTECHNOLOGY
  • 2003-09. Mechanism and regulation of human non-homologous DNA end-joining in NATURE REVIEWS MOLECULAR CELL BIOLOGY
  • 2010-10-24. Recombinase technology: applications and possibilities in PLANT CELL REPORTS
  • 2011-08-01. Heritable gene targeting in zebrafish using customized TALENs in NATURE BIOTECHNOLOGY
  • 2001-12-01. A peptide carrier for the delivery of biologically active proteins into mammalian cells in NATURE BIOTECHNOLOGY
  • 2011-01-01. Targeted integration in rat and mouse embryos with zinc-finger nucleases in NATURE BIOTECHNOLOGY
  • 2013-06-23. Image-based analysis of lipid nanoparticle–mediated siRNA delivery, intracellular trafficking and endosomal escape in NATURE BIOTECHNOLOGY
  • 2012-09-23. In vivo genome editing using a high-efficiency TALEN system in NATURE
  • 2003-05. Drug discovery with engineered zinc-finger proteins in NATURE REVIEWS DRUG DISCOVERY
  • 2006-04-01. An Overview of Cytidine Deaminases in INTERNATIONAL JOURNAL OF HEMATOLOGY
  • 2014-07-08. First CRISPR-Cas patent opens race to stake out intellectual property in NATURE BIOTECHNOLOGY
  • 2014-03-30. Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype in NATURE BIOTECHNOLOGY
  • 1999-08-01. Stabilized plasmid-lipid particles for regional gene therapy: formulation and transfection properties in GENE THERAPY
  • 2006-01-15. Crystal structure of Staphylococcus aureus tRNA adenosine deaminase TadA in complex with RNA in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2007-10-28. Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery in NATURE BIOTECHNOLOGY
  • 2008-10-12. Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications in NATURE
  • 2014-04-20. Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells in NATURE BIOTECHNOLOGY
  • 2017-03-27. Targeted base editing in rice and tomato using a CRISPR-Cas9 cytidine deaminase fusion in NATURE BIOTECHNOLOGY
  • 2009-01-21. DNA Repair in Mammalian Cells in CELLULAR AND MOLECULAR LIFE SCIENCES
  • 2014-01-26. Improving CRISPR-Cas nuclease specificity using truncated guide RNAs in NATURE BIOTECHNOLOGY
  • 2015-04-06. Small molecule–triggered Cas9 protein with improved genome-editing specificity in NATURE CHEMICAL BIOLOGY
  • 2011-12-01. Safe harbours for the integration of new DNA in the human genome in NATURE REVIEWS CANCER
  • 2011-08-01. Genetic engineering of human pluripotent cells using TALE nucleases in NATURE BIOTECHNOLOGY
  • 2012-09-10. RNA-mediated programmable DNA cleavage in NATURE BIOTECHNOLOGY
  • 2016-12-22. New CRISPR–Cas systems from uncultivated microbes in NATURE
  • 2014-09-05. The evolutionary journey of Argonaute proteins in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2011-04-03. Structural basis for CRISPR RNA-guided DNA recognition by Cascade in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2008-08. Single-strand break repair and genetic disease in NATURE REVIEWS GENETICS
  • 2008. Chromosomal Mutagenesis in NONE
  • 2014-07-31. The RNA editing enzyme APOBEC1 induces somatic mutations and a compatible mutational signature is present in esophageal adenocarcinomas in GENOME BIOLOGY
  • 2008-05. Unexpected failure rates for modular assembly of engineered zinc fingers in NATURE METHODS
  • 2013-08-01. CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering in NATURE BIOTECHNOLOGY
  • 2013-08-11. High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity in NATURE BIOTECHNOLOGY
  • 2008-06-17. The AID/APOBEC family of nucleic acid mutators in GENOME BIOLOGY
  • 2015-11-02. Broadening the targeting range of Staphylococcus aureus CRISPR-Cas9 by modifying PAM recognition in NATURE BIOTECHNOLOGY
  • 1999-07. Characterization of single-nucleotide polymorphisms in coding regions of human genes in NATURE GENETICS
  • 2001-11. Alteration of Cre recombinase site specificity by substrate-linked protein evolution in NATURE BIOTECHNOLOGY
  • 2016-01-20. Enhancing homology-directed genome editing by catalytically active and inactive CRISPR-Cas9 using asymmetric donor DNA in NATURE BIOTECHNOLOGY
  • 2016-04-20. Gene-editing hack yields pinpoint precision in NATURE
  • 2004-02-08. Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis in NATURE MEDICINE
  • 2008-05-25. Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases in NATURE BIOTECHNOLOGY
  • 2017-04-10. Genome-wide target specificities of CRISPR RNA-guided programmable deaminases in NATURE BIOTECHNOLOGY
  • 2012-10-23. Biological and Biomedical Applications of Engineered Nucleases in MOLECULAR BIOTECHNOLOGY
  • 2011-08-01. Knockout rats generated by embryo microinjection of TALENs in NATURE BIOTECHNOLOGY
  • 2014-10-30. Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo in NATURE BIOTECHNOLOGY
  • 2014-04-25. Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification in NATURE BIOTECHNOLOGY
  • 2014-04-25. Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing in NATURE BIOTECHNOLOGY
  • 2008-09-11. Progress and prospects: Zinc-finger nucleases as gene therapy agents in GENE THERAPY
  • 2009-05-15. Site-Specific Recombinases for Manipulation of the Mouse Genome in TRANSGENESIS TECHNIQUES
  • 2015-03-02. Highly efficient Cas9-mediated transcriptional programming in NATURE METHODS
  • 2016-09-26. Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection in NATURE
  • 2009. Transgenesis Techniques, Principles and Protocols in NONE
  • 2004-12-20. PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas in ONCOGENE
  • 2012-04-08. FLASH assembly of TALENs for high-throughput genome editing in NATURE BIOTECHNOLOGY
  • 2009-10. Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes in NATURE
  • 2013-07-25. CRISPR RNA–guided activation of endogenous human genes in NATURE METHODS
  • 2014-03-22. Fidelity of end joining in mammalian episomes and the impact of Metnase on joint processing in BMC MOLECULAR AND CELL BIOLOGY
  • 2017-06-06. Improving the DNA specificity and applicability of base editing through protein engineering and protein delivery in NATURE COMMUNICATIONS
  • 2008-06-29. Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases in NATURE BIOTECHNOLOGY
  • 2014-05-18. Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease in NATURE BIOTECHNOLOGY
  • 2008. Gene Targeting in Drosophila and Caenorhabditis elegans With Zinc-Finger Nucleases in CHROMOSOMAL MUTAGENESIS
  • 2016-09-05. A multifunctional AAV–CRISPR–Cas9 and its host response in NATURE METHODS
  • 2011-05-09. Evolution and classification of the CRISPR–Cas systems in NATURE REVIEWS MICROBIOLOGY
  • 2016-05-02. DNA-guided genome editing using the Natronobacterium gregoryi Argonaute in NATURE BIOTECHNOLOGY
  • 2016-01-06. High-fidelity CRISPR–Cas9 nucleases with no detectable genome-wide off-target effects in NATURE
  • 2009-08-13. Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases in NATURE BIOTECHNOLOGY
  • 2013-10-17. CRISPR interference (CRISPRi) for sequence-specific control of gene expression in NATURE PROTOCOLS
  • 2011-05-13. ZFN-Site searches genomes for zinc finger nuclease target sites and off-target sites in BMC BIOINFORMATICS
  • 2015-09-28. An updated evolutionary classification of CRISPR–Cas systems in NATURE REVIEWS MICROBIOLOGY
  • 2011-01-19. Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription in NATURE BIOTECHNOLOGY
  • 2007-07-01. Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases in NATURE BIOTECHNOLOGY
  • 2007-07-01. An improved zinc-finger nuclease architecture for highly specific genome editing in NATURE BIOTECHNOLOGY
  • 2010-11-03. The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA in NATURE
  • 2008-05-25. Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases in NATURE BIOTECHNOLOGY
  • 2008-02-20. Structure of the DNA deaminase domain of the HIV-1 restriction factor APOBEC3G in NATURE
  • 2013-07-25. RNA-guided gene activation by CRISPR-Cas9–based transcription factors in NATURE METHODS
  • 2013-09-29. Orthogonal Cas9 proteins for RNA-guided gene regulation and editing in NATURE METHODS
  • 2017-06-05. CRISPR-STOP: gene silencing through base-editing-induced nonsense mutations in NATURE METHODS
  • 2010-09. Genome editing with engineered zinc finger nucleases in NATURE REVIEWS GENETICS
  • 2006-05-14. Backbone and nucleobase contacts to glucosamine-6-phosphate in the glmS ribozyme in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2014-03-02. CRISPR-Cas systems for editing, regulating and targeting genomes in NATURE BIOTECHNOLOGY
  • 2013-03-06. Rewriting a genome in NATURE
  • 2013-07-21. DNA targeting specificity of RNA-guided Cas9 nucleases in NATURE BIOTECHNOLOGY
  • 2010-01-17. Rational design of cationic lipids for siRNA delivery in NATURE BIOTECHNOLOGY
  • 2017-02-13. Increasing the genome-targeting scope and precision of base editing with engineered Cas9-cytidine deaminase fusions in NATURE BIOTECHNOLOGY
  • 2015-02-02. A split-Cas9 architecture for inducible genome editing and transcription modulation in NATURE BIOTECHNOLOGY
  • 2011-02-07. TALEs of genome targeting in NATURE BIOTECHNOLOGY
  • 2011-02-07. Gene therapy finds its niche in NATURE BIOTECHNOLOGY
  • 2006-11-08. Replisome assembly and the direct restart of stalled replication forks in NATURE REVIEWS MOLECULAR CELL BIOLOGY
  • 2013-08-14. Signatures of mutational processes in human cancer in NATURE
  • 2016-11-02. Engineering and optimising deaminase fusions for genome editing in NATURE COMMUNICATIONS
  • JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "name": "LIU DAVID R", 
            "type": "Person"
          }, 
          {
            "name": "GAUDELLI NICOLE", 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1038/nbt.1769", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053580569", 
              "https://doi.org/10.1038/nbt.1769"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/495050a", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027212057", 
              "https://doi.org/10.1038/495050a"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nmeth0508-374", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021094033", 
              "https://doi.org/10.1038/nmeth0508-374"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nsmb.2019", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011829375", 
              "https://doi.org/10.1038/nsmb.2019"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nmeth.4027", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038829252", 
              "https://doi.org/10.1038/nmeth.4027"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.2889", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043519930", 
              "https://doi.org/10.1038/nbt.2889"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nmeth.2845", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002278800", 
              "https://doi.org/10.1038/nmeth.2845"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt1319", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002154526", 
              "https://doi.org/10.1038/nbt1319"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00360521", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038349147", 
              "https://doi.org/10.1007/bf00360521"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nmeth.2366", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040994508", 
              "https://doi.org/10.1038/nmeth.2366"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature12477", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050004918", 
              "https://doi.org/10.1038/nature12477"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.1602", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051671503", 
              "https://doi.org/10.1038/nbt.1602"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.3753", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011440933", 
              "https://doi.org/10.1038/nbt.3753"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s13238-017-0458-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1091243310", 
              "https://doi.org/10.1007/s13238-017-0458-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.2508", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019888616", 
              "https://doi.org/10.1038/nbt.2508"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.1940", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051218365", 
              "https://doi.org/10.1038/nbt.1940"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature13011", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037342101", 
              "https://doi.org/10.1038/nature13011"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s004390050904", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035082076", 
              "https://doi.org/10.1007/s004390050904"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.2647", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012543463", 
              "https://doi.org/10.1038/nbt.2647"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature09523", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009515358", 
              "https://doi.org/10.1038/nature09523"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrmicro2577", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020345829", 
              "https://doi.org/10.1038/nrmicro2577"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1471-2105-12-15", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002905857", 
              "https://doi.org/10.1186/1471-2105-12-15"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nmeth.2649", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008703730", 
              "https://doi.org/10.1038/nmeth.2649"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.2909", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053226125", 
              "https://doi.org/10.1038/nbt.2909"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature19802", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012203082", 
              "https://doi.org/10.1038/nature19802"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrm2058", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005655334", 
              "https://doi.org/10.1038/nrm2058"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.2675", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041659759", 
              "https://doi.org/10.1038/nbt.2675"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.2507", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041881936", 
              "https://doi.org/10.1038/nbt.2507"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ncomms13330", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024993788", 
              "https://doi.org/10.1038/ncomms13330"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nmeth.4038", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030846996", 
              "https://doi.org/10.1038/nmeth.4038"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature06638", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015857224", 
              "https://doi.org/10.1038/nature06638"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nm.3793", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052797737", 
              "https://doi.org/10.1038/nm.3793"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/gb-2011-12-11-r112", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027516867", 
              "https://doi.org/10.1186/gb-2011-12-11-r112"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nprot.2011.431", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020679703", 
              "https://doi.org/10.1038/nprot.2011.431"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/978-1-60327-019-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045514102", 
              "https://doi.org/10.1007/978-1-60327-019-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrg2842", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018939216", 
              "https://doi.org/10.1038/nrg2842"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.3404", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052861805", 
              "https://doi.org/10.1038/nbt.3404"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/gt.2008.145", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045636817", 
              "https://doi.org/10.1038/gt.2008.145"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.2623", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009511624", 
              "https://doi.org/10.1038/nbt.2623"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature11017", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034041413", 
              "https://doi.org/10.1038/nature11017"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nmeth.1670", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043918422", 
              "https://doi.org/10.1038/nmeth.1670"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.3803", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1083803971", 
              "https://doi.org/10.1038/nbt.3803"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.3198", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008895789", 
              "https://doi.org/10.1038/nbt.3198"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/978-1-59745-232-8_4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040102050", 
              "https://doi.org/10.1007/978-1-59745-232-8_4"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nsmb.2879", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010082311", 
              "https://doi.org/10.1038/nsmb.2879"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1471-2199-15-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018784555", 
              "https://doi.org/10.1186/1471-2199-15-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature08434", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042379011", 
              "https://doi.org/10.1038/nature08434"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.onc.1208304", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036710331", 
              "https://doi.org/10.1038/sj.onc.1208304"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.3816", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1084128652", 
              "https://doi.org/10.1038/nbt.3816"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nmeth.4327", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1085864346", 
              "https://doi.org/10.1038/nmeth.4327"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nmeth.2600", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024354143", 
              "https://doi.org/10.1038/nmeth.2600"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature11537", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021191816", 
              "https://doi.org/10.1038/nature11537"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrm3486", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050461034", 
              "https://doi.org/10.1038/nrm3486"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature07357", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003765537", 
              "https://doi.org/10.1038/nature07357"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1471-2105-12-152", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031107821", 
              "https://doi.org/10.1186/1471-2105-12-152"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nprot.2013.143", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016534425", 
              "https://doi.org/10.1038/nprot.2013.143"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00299-010-0938-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044696716", 
              "https://doi.org/10.1007/s00299-010-0938-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.1767", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022298591", 
              "https://doi.org/10.1038/nbt.1767"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nmeth.2364", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015862962", 
              "https://doi.org/10.1038/nmeth.2364"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s13238-014-0032-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051855442", 
              "https://doi.org/10.1007/s13238-014-0032-5"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nsmb1047", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005930818", 
              "https://doi.org/10.1038/nsmb1047"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.2884", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011531387", 
              "https://doi.org/10.1038/nbt.2884"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature21059", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023889809", 
              "https://doi.org/10.1038/nature21059"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/978-1-59745-232-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011938717", 
              "https://doi.org/10.1007/978-1-59745-232-8"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.3547", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047211077", 
              "https://doi.org/10.1038/nbt.3547"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.3833", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1084128666", 
              "https://doi.org/10.1038/nbt.3833"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.1731", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030230970", 
              "https://doi.org/10.1038/nbt.1731"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nmeth.3312", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008897838", 
              "https://doi.org/10.1038/nmeth.3312"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.3467", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020093829", 
              "https://doi.org/10.1038/nbt.3467"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1532/ijh97.06032", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041769571", 
              "https://doi.org/10.1532/ijh97.06032"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature10886", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053669571", 
              "https://doi.org/10.1038/nature10886"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrd1087", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040287926", 
              "https://doi.org/10.1038/nrd1087"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.3117", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021849416", 
              "https://doi.org/10.1038/nbt.3117"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.2170", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040026920", 
              "https://doi.org/10.1038/nbt.2170"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.3190", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017538548", 
              "https://doi.org/10.1038/nbt.3190"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt1398", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032856466", 
              "https://doi.org/10.1038/nbt1398"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt1410", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048577624", 
              "https://doi.org/10.1038/nbt1410"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature.2016.19773", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1056448921", 
              "https://doi.org/10.1038/nature.2016.19773"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.2916", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043348902", 
              "https://doi.org/10.1038/nbt.2916"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/gt.2015.30", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005185460", 
              "https://doi.org/10.1038/gt.2015.30"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/srep10777", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049485171", 
              "https://doi.org/10.1038/srep10777"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature09886", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030591890", 
              "https://doi.org/10.1038/nature09886"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00018-009-8739-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018493026", 
              "https://doi.org/10.1007/s00018-009-8739-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/978-1-59745-232-8_5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043561019", 
              "https://doi.org/10.1007/978-1-59745-232-8_5"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.1934", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010658010", 
              "https://doi.org/10.1038/nbt.1934"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nmeth.2681", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028304735", 
              "https://doi.org/10.1038/nmeth.2681"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.2501", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024988605", 
              "https://doi.org/10.1038/nbt.2501"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.2842", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038520013", 
              "https://doi.org/10.1038/nbt.2842"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.2808", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048637524", 
              "https://doi.org/10.1038/nbt.2808"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nmeth.3993", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016047103", 
              "https://doi.org/10.1038/nmeth.3993"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1631/jzus.b1200042", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038506352", 
              "https://doi.org/10.1631/jzus.b1200042"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrmicro3569", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010036058", 
              "https://doi.org/10.1038/nrmicro3569"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.3852", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1084753472", 
              "https://doi.org/10.1038/nbt.3852"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature13769", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009875984", 
              "https://doi.org/10.1038/nature13769"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.3149", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034330725", 
              "https://doi.org/10.1038/nbt.3149"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/978-1-60327-019-9_16", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040082301", 
              "https://doi.org/10.1007/978-1-60327-019-9_16"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.3481", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004939292", 
              "https://doi.org/10.1038/nbt.3481"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrc3179", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052351170", 
              "https://doi.org/10.1038/nrc3179"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt1353", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026122095", 
              "https://doi.org/10.1038/nbt1353"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature14299", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019168198", 
              "https://doi.org/10.1038/nature14299"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/10290", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008973203", 
              "https://doi.org/10.1038/10290"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nchembio832", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040735018", 
              "https://doi.org/10.1038/nchembio832"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature12971", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052410148", 
              "https://doi.org/10.1038/nature12971"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt1101-1047", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023451333", 
              "https://doi.org/10.1038/nbt1101-1047"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13059-014-0417-z", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025106002", 
              "https://doi.org/10.1186/s13059-014-0417-z"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.3081", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017697957", 
              "https://doi.org/10.1038/nbt.3081"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nsmb1094", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015513776", 
              "https://doi.org/10.1038/nsmb1094"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nmeth.2598", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049500416", 
              "https://doi.org/10.1038/nmeth.2598"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt1201-1173", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033003564", 
              "https://doi.org/10.1038/nbt1201-1173"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ncomms15790", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1085880702", 
              "https://doi.org/10.1038/ncomms15790"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature14592", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047292250", 
              "https://doi.org/10.1038/nature14592"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/s41467-017-00175-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1090780642", 
              "https://doi.org/10.1038/s41467-017-00175-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature17946", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009172001", 
              "https://doi.org/10.1038/nature17946"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrm1202", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010441359", 
              "https://doi.org/10.1038/nrm1202"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nm996", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040467981", 
              "https://doi.org/10.1038/nm996"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.1775", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031104364", 
              "https://doi.org/10.1038/nbt.1775"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00239-004-0046-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053505023", 
              "https://doi.org/10.1007/s00239-004-0046-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nmeth.2521", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025077524", 
              "https://doi.org/10.1038/nmeth.2521"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/gb-2008-9-6-229", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021664284", 
              "https://doi.org/10.1186/gb-2008-9-6-229"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12033-012-9613-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031558495", 
              "https://doi.org/10.1007/s12033-012-9613-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature03556", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040117781", 
              "https://doi.org/10.1038/nature03556"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.2673", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007302590", 
              "https://doi.org/10.1038/nbt.2673"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature13579", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036390967", 
              "https://doi.org/10.1038/nature13579"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.1562", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033826570", 
              "https://doi.org/10.1038/nbt.1562"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.gt.3300965", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048788770", 
              "https://doi.org/10.1038/sj.gt.3300965"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.2357", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014043446", 
              "https://doi.org/10.1038/nbt.2357"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.1927", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047844983", 
              "https://doi.org/10.1038/nbt.1927"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s13205-012-0088-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045092325", 
              "https://doi.org/10.1007/s13205-012-0088-y"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.1939", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010610351", 
              "https://doi.org/10.1038/nbt.1939"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt1317", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045480104", 
              "https://doi.org/10.1038/nbt1317"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.2517", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017042091", 
              "https://doi.org/10.1038/nbt.2517"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nsmb.1744", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002558962", 
              "https://doi.org/10.1038/nsmb.1744"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.2908", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012868720", 
              "https://doi.org/10.1038/nbt.2908"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10162-012-0324-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019406988", 
              "https://doi.org/10.1007/s10162-012-0324-5"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.1755", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016004947", 
              "https://doi.org/10.1038/nbt.1755"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/s13059-015-0584-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024223648", 
              "https://doi.org/10.1186/s13059-015-0584-6"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature16526", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010800066", 
              "https://doi.org/10.1038/nature16526"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt0714-599", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049485528", 
              "https://doi.org/10.1038/nbt0714-599"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.2612", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003176820", 
              "https://doi.org/10.1038/nbt.2612"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nprot.2013.132", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009361018", 
              "https://doi.org/10.1038/nprot.2013.132"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt1409", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045837461", 
              "https://doi.org/10.1038/nbt1409"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt.3811", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1084128647", 
              "https://doi.org/10.1038/nbt.3811"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nchembio.1793", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042535273", 
              "https://doi.org/10.1038/nchembio.1793"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrneurol.2012.263", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005735277", 
              "https://doi.org/10.1038/nrneurol.2012.263"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrg2380", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041270694", 
              "https://doi.org/10.1038/nrg2380"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2018-10-30T00:00", 
        "description": "

    The disclosure provides adenosine deaminases that are capable of deaminating adenosine in DNA. The disclosure also provides fusion proteins comprising a Cas9 (e.g., a Cas9 nickase) domain and adenosine deaminases that deaminate adenosine in DNA. In some embodiments, the fusion proteins further comprise a nuclear localization sequence (NLS), and/or an inhibitor of base repair, such as, a nuclease dead inosine specific nuclease (dISN).

    ", "endDate": "2037-08-03", "id": "sg:patent.US-10113163-B2", "name": "Adenosine nucleobase editors and uses thereof", "recipient": [ { "id": "http://www.grid.ac/institutes/grid.38142.3c", "type": "Organization" } ], "sameAs": [ "https://app.dimensions.ai/details/patent/US-10113163-B2" ], "sdDataset": "patents", "sdDatePublished": "2022-09-02T16:21", "sdLicense": "https://scigraph.springernature.com/explorer/license/", "sdPublisher": { "name": "Springer Nature - SN SciGraph project", "type": "Organization" }, "sdSource": "s3://com-springernature-scigraph/baseset/20220902/entities/gbq_results/patent/patent_39.jsonl", "type": "Patent" } ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/patent.US-10113163-B2'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/patent.US-10113163-B2'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/patent.US-10113163-B2'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/patent.US-10113163-B2'


     

    This table displays all metadata directly associated to this object as RDF triples.

    610 TRIPLES      15 PREDICATES      161 URIs      9 LITERALS      2 BLANK NODES

    Subject Predicate Object
    1 sg:patent.US-10113163-B2 schema:about anzsrc-for:06
    2 anzsrc-for:0601
    3 schema:author N060eafe317664a418a06711459e1c0e9
    4 schema:citation sg:pub.10.1007/978-1-59745-232-8
    5 sg:pub.10.1007/978-1-59745-232-8_4
    6 sg:pub.10.1007/978-1-59745-232-8_5
    7 sg:pub.10.1007/978-1-60327-019-9
    8 sg:pub.10.1007/978-1-60327-019-9_16
    9 sg:pub.10.1007/bf00360521
    10 sg:pub.10.1007/s00018-009-8739-9
    11 sg:pub.10.1007/s00239-004-0046-3
    12 sg:pub.10.1007/s00299-010-0938-1
    13 sg:pub.10.1007/s004390050904
    14 sg:pub.10.1007/s10162-012-0324-5
    15 sg:pub.10.1007/s12033-012-9613-9
    16 sg:pub.10.1007/s13205-012-0088-y
    17 sg:pub.10.1007/s13238-014-0032-5
    18 sg:pub.10.1007/s13238-017-0458-7
    19 sg:pub.10.1038/10290
    20 sg:pub.10.1038/495050a
    21 sg:pub.10.1038/gt.2008.145
    22 sg:pub.10.1038/gt.2015.30
    23 sg:pub.10.1038/nature.2016.19773
    24 sg:pub.10.1038/nature03556
    25 sg:pub.10.1038/nature06638
    26 sg:pub.10.1038/nature07357
    27 sg:pub.10.1038/nature08434
    28 sg:pub.10.1038/nature09523
    29 sg:pub.10.1038/nature09886
    30 sg:pub.10.1038/nature10886
    31 sg:pub.10.1038/nature11017
    32 sg:pub.10.1038/nature11537
    33 sg:pub.10.1038/nature12477
    34 sg:pub.10.1038/nature12971
    35 sg:pub.10.1038/nature13011
    36 sg:pub.10.1038/nature13579
    37 sg:pub.10.1038/nature13769
    38 sg:pub.10.1038/nature14299
    39 sg:pub.10.1038/nature14592
    40 sg:pub.10.1038/nature16526
    41 sg:pub.10.1038/nature17946
    42 sg:pub.10.1038/nature19802
    43 sg:pub.10.1038/nature21059
    44 sg:pub.10.1038/nbt.1562
    45 sg:pub.10.1038/nbt.1602
    46 sg:pub.10.1038/nbt.1731
    47 sg:pub.10.1038/nbt.1755
    48 sg:pub.10.1038/nbt.1767
    49 sg:pub.10.1038/nbt.1769
    50 sg:pub.10.1038/nbt.1775
    51 sg:pub.10.1038/nbt.1927
    52 sg:pub.10.1038/nbt.1934
    53 sg:pub.10.1038/nbt.1939
    54 sg:pub.10.1038/nbt.1940
    55 sg:pub.10.1038/nbt.2170
    56 sg:pub.10.1038/nbt.2357
    57 sg:pub.10.1038/nbt.2501
    58 sg:pub.10.1038/nbt.2507
    59 sg:pub.10.1038/nbt.2508
    60 sg:pub.10.1038/nbt.2517
    61 sg:pub.10.1038/nbt.2612
    62 sg:pub.10.1038/nbt.2623
    63 sg:pub.10.1038/nbt.2647
    64 sg:pub.10.1038/nbt.2673
    65 sg:pub.10.1038/nbt.2675
    66 sg:pub.10.1038/nbt.2808
    67 sg:pub.10.1038/nbt.2842
    68 sg:pub.10.1038/nbt.2884
    69 sg:pub.10.1038/nbt.2889
    70 sg:pub.10.1038/nbt.2908
    71 sg:pub.10.1038/nbt.2909
    72 sg:pub.10.1038/nbt.2916
    73 sg:pub.10.1038/nbt.3081
    74 sg:pub.10.1038/nbt.3117
    75 sg:pub.10.1038/nbt.3149
    76 sg:pub.10.1038/nbt.3190
    77 sg:pub.10.1038/nbt.3198
    78 sg:pub.10.1038/nbt.3404
    79 sg:pub.10.1038/nbt.3467
    80 sg:pub.10.1038/nbt.3481
    81 sg:pub.10.1038/nbt.3547
    82 sg:pub.10.1038/nbt.3753
    83 sg:pub.10.1038/nbt.3803
    84 sg:pub.10.1038/nbt.3811
    85 sg:pub.10.1038/nbt.3816
    86 sg:pub.10.1038/nbt.3833
    87 sg:pub.10.1038/nbt.3852
    88 sg:pub.10.1038/nbt0714-599
    89 sg:pub.10.1038/nbt1101-1047
    90 sg:pub.10.1038/nbt1201-1173
    91 sg:pub.10.1038/nbt1317
    92 sg:pub.10.1038/nbt1319
    93 sg:pub.10.1038/nbt1353
    94 sg:pub.10.1038/nbt1398
    95 sg:pub.10.1038/nbt1409
    96 sg:pub.10.1038/nbt1410
    97 sg:pub.10.1038/nchembio.1793
    98 sg:pub.10.1038/nchembio832
    99 sg:pub.10.1038/ncomms13330
    100 sg:pub.10.1038/ncomms15790
    101 sg:pub.10.1038/nm.3793
    102 sg:pub.10.1038/nm996
    103 sg:pub.10.1038/nmeth.1670
    104 sg:pub.10.1038/nmeth.2364
    105 sg:pub.10.1038/nmeth.2366
    106 sg:pub.10.1038/nmeth.2521
    107 sg:pub.10.1038/nmeth.2598
    108 sg:pub.10.1038/nmeth.2600
    109 sg:pub.10.1038/nmeth.2649
    110 sg:pub.10.1038/nmeth.2681
    111 sg:pub.10.1038/nmeth.2845
    112 sg:pub.10.1038/nmeth.3312
    113 sg:pub.10.1038/nmeth.3993
    114 sg:pub.10.1038/nmeth.4027
    115 sg:pub.10.1038/nmeth.4038
    116 sg:pub.10.1038/nmeth.4327
    117 sg:pub.10.1038/nmeth0508-374
    118 sg:pub.10.1038/nprot.2011.431
    119 sg:pub.10.1038/nprot.2013.132
    120 sg:pub.10.1038/nprot.2013.143
    121 sg:pub.10.1038/nrc3179
    122 sg:pub.10.1038/nrd1087
    123 sg:pub.10.1038/nrg2380
    124 sg:pub.10.1038/nrg2842
    125 sg:pub.10.1038/nrm1202
    126 sg:pub.10.1038/nrm2058
    127 sg:pub.10.1038/nrm3486
    128 sg:pub.10.1038/nrmicro2577
    129 sg:pub.10.1038/nrmicro3569
    130 sg:pub.10.1038/nrneurol.2012.263
    131 sg:pub.10.1038/nsmb.1744
    132 sg:pub.10.1038/nsmb.2019
    133 sg:pub.10.1038/nsmb.2879
    134 sg:pub.10.1038/nsmb1047
    135 sg:pub.10.1038/nsmb1094
    136 sg:pub.10.1038/s41467-017-00175-6
    137 sg:pub.10.1038/sj.gt.3300965
    138 sg:pub.10.1038/sj.onc.1208304
    139 sg:pub.10.1038/srep10777
    140 sg:pub.10.1186/1471-2105-12-15
    141 sg:pub.10.1186/1471-2105-12-152
    142 sg:pub.10.1186/1471-2199-15-6
    143 sg:pub.10.1186/gb-2008-9-6-229
    144 sg:pub.10.1186/gb-2011-12-11-r112
    145 sg:pub.10.1186/s13059-014-0417-z
    146 sg:pub.10.1186/s13059-015-0584-6
    147 sg:pub.10.1532/ijh97.06032
    148 sg:pub.10.1631/jzus.b1200042
    149 schema:datePublished 2018-10-30T00:00
    150 schema:description <p id="p-0001" num="0000">The disclosure provides adenosine deaminases that are capable of deaminating adenosine in DNA. The disclosure also provides fusion proteins comprising a Cas9 (e.g., a Cas9 nickase) domain and adenosine deaminases that deaminate adenosine in DNA. In some embodiments, the fusion proteins further comprise a nuclear localization sequence (NLS), and/or an inhibitor of base repair, such as, a nuclease dead inosine specific nuclease (dISN).</p>
    151 schema:endDate 2037-08-03
    152 schema:name Adenosine nucleobase editors and uses thereof
    153 schema:recipient grid-institutes:grid.38142.3c
    154 schema:sameAs https://app.dimensions.ai/details/patent/US-10113163-B2
    155 schema:sdDatePublished 2022-09-02T16:21
    156 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    157 schema:sdPublisher N74e36be75158413b8882c2757bc97a81
    158 sgo:license sg:explorer/license/
    159 sgo:sdDataset patents
    160 rdf:type sgo:Patent
    161 N060eafe317664a418a06711459e1c0e9 rdf:first Naed7ae06109743f9b51c7052259c46dc
    162 rdf:rest Nd8a3b6f949134a238feca4cc739348bb
    163 N12e4479f208040ceba995065a980cffd schema:name GAUDELLI NICOLE
    164 rdf:type schema:Person
    165 N74e36be75158413b8882c2757bc97a81 schema:name Springer Nature - SN SciGraph project
    166 rdf:type schema:Organization
    167 Naed7ae06109743f9b51c7052259c46dc schema:name LIU DAVID R
    168 rdf:type schema:Person
    169 Nd8a3b6f949134a238feca4cc739348bb rdf:first N12e4479f208040ceba995065a980cffd
    170 rdf:rest rdf:nil
    171 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
    172 rdf:type schema:DefinedTerm
    173 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
    174 rdf:type schema:DefinedTerm
    175 sg:pub.10.1007/978-1-59745-232-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011938717
    176 https://doi.org/10.1007/978-1-59745-232-8
    177 rdf:type schema:CreativeWork
    178 sg:pub.10.1007/978-1-59745-232-8_4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040102050
    179 https://doi.org/10.1007/978-1-59745-232-8_4
    180 rdf:type schema:CreativeWork
    181 sg:pub.10.1007/978-1-59745-232-8_5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043561019
    182 https://doi.org/10.1007/978-1-59745-232-8_5
    183 rdf:type schema:CreativeWork
    184 sg:pub.10.1007/978-1-60327-019-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045514102
    185 https://doi.org/10.1007/978-1-60327-019-9
    186 rdf:type schema:CreativeWork
    187 sg:pub.10.1007/978-1-60327-019-9_16 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040082301
    188 https://doi.org/10.1007/978-1-60327-019-9_16
    189 rdf:type schema:CreativeWork
    190 sg:pub.10.1007/bf00360521 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038349147
    191 https://doi.org/10.1007/bf00360521
    192 rdf:type schema:CreativeWork
    193 sg:pub.10.1007/s00018-009-8739-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018493026
    194 https://doi.org/10.1007/s00018-009-8739-9
    195 rdf:type schema:CreativeWork
    196 sg:pub.10.1007/s00239-004-0046-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053505023
    197 https://doi.org/10.1007/s00239-004-0046-3
    198 rdf:type schema:CreativeWork
    199 sg:pub.10.1007/s00299-010-0938-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044696716
    200 https://doi.org/10.1007/s00299-010-0938-1
    201 rdf:type schema:CreativeWork
    202 sg:pub.10.1007/s004390050904 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035082076
    203 https://doi.org/10.1007/s004390050904
    204 rdf:type schema:CreativeWork
    205 sg:pub.10.1007/s10162-012-0324-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019406988
    206 https://doi.org/10.1007/s10162-012-0324-5
    207 rdf:type schema:CreativeWork
    208 sg:pub.10.1007/s12033-012-9613-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031558495
    209 https://doi.org/10.1007/s12033-012-9613-9
    210 rdf:type schema:CreativeWork
    211 sg:pub.10.1007/s13205-012-0088-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1045092325
    212 https://doi.org/10.1007/s13205-012-0088-y
    213 rdf:type schema:CreativeWork
    214 sg:pub.10.1007/s13238-014-0032-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051855442
    215 https://doi.org/10.1007/s13238-014-0032-5
    216 rdf:type schema:CreativeWork
    217 sg:pub.10.1007/s13238-017-0458-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1091243310
    218 https://doi.org/10.1007/s13238-017-0458-7
    219 rdf:type schema:CreativeWork
    220 sg:pub.10.1038/10290 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008973203
    221 https://doi.org/10.1038/10290
    222 rdf:type schema:CreativeWork
    223 sg:pub.10.1038/495050a schema:sameAs https://app.dimensions.ai/details/publication/pub.1027212057
    224 https://doi.org/10.1038/495050a
    225 rdf:type schema:CreativeWork
    226 sg:pub.10.1038/gt.2008.145 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045636817
    227 https://doi.org/10.1038/gt.2008.145
    228 rdf:type schema:CreativeWork
    229 sg:pub.10.1038/gt.2015.30 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005185460
    230 https://doi.org/10.1038/gt.2015.30
    231 rdf:type schema:CreativeWork
    232 sg:pub.10.1038/nature.2016.19773 schema:sameAs https://app.dimensions.ai/details/publication/pub.1056448921
    233 https://doi.org/10.1038/nature.2016.19773
    234 rdf:type schema:CreativeWork
    235 sg:pub.10.1038/nature03556 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040117781
    236 https://doi.org/10.1038/nature03556
    237 rdf:type schema:CreativeWork
    238 sg:pub.10.1038/nature06638 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015857224
    239 https://doi.org/10.1038/nature06638
    240 rdf:type schema:CreativeWork
    241 sg:pub.10.1038/nature07357 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003765537
    242 https://doi.org/10.1038/nature07357
    243 rdf:type schema:CreativeWork
    244 sg:pub.10.1038/nature08434 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042379011
    245 https://doi.org/10.1038/nature08434
    246 rdf:type schema:CreativeWork
    247 sg:pub.10.1038/nature09523 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009515358
    248 https://doi.org/10.1038/nature09523
    249 rdf:type schema:CreativeWork
    250 sg:pub.10.1038/nature09886 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030591890
    251 https://doi.org/10.1038/nature09886
    252 rdf:type schema:CreativeWork
    253 sg:pub.10.1038/nature10886 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053669571
    254 https://doi.org/10.1038/nature10886
    255 rdf:type schema:CreativeWork
    256 sg:pub.10.1038/nature11017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034041413
    257 https://doi.org/10.1038/nature11017
    258 rdf:type schema:CreativeWork
    259 sg:pub.10.1038/nature11537 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021191816
    260 https://doi.org/10.1038/nature11537
    261 rdf:type schema:CreativeWork
    262 sg:pub.10.1038/nature12477 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050004918
    263 https://doi.org/10.1038/nature12477
    264 rdf:type schema:CreativeWork
    265 sg:pub.10.1038/nature12971 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052410148
    266 https://doi.org/10.1038/nature12971
    267 rdf:type schema:CreativeWork
    268 sg:pub.10.1038/nature13011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037342101
    269 https://doi.org/10.1038/nature13011
    270 rdf:type schema:CreativeWork
    271 sg:pub.10.1038/nature13579 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036390967
    272 https://doi.org/10.1038/nature13579
    273 rdf:type schema:CreativeWork
    274 sg:pub.10.1038/nature13769 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009875984
    275 https://doi.org/10.1038/nature13769
    276 rdf:type schema:CreativeWork
    277 sg:pub.10.1038/nature14299 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019168198
    278 https://doi.org/10.1038/nature14299
    279 rdf:type schema:CreativeWork
    280 sg:pub.10.1038/nature14592 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047292250
    281 https://doi.org/10.1038/nature14592
    282 rdf:type schema:CreativeWork
    283 sg:pub.10.1038/nature16526 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010800066
    284 https://doi.org/10.1038/nature16526
    285 rdf:type schema:CreativeWork
    286 sg:pub.10.1038/nature17946 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009172001
    287 https://doi.org/10.1038/nature17946
    288 rdf:type schema:CreativeWork
    289 sg:pub.10.1038/nature19802 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012203082
    290 https://doi.org/10.1038/nature19802
    291 rdf:type schema:CreativeWork
    292 sg:pub.10.1038/nature21059 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023889809
    293 https://doi.org/10.1038/nature21059
    294 rdf:type schema:CreativeWork
    295 sg:pub.10.1038/nbt.1562 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033826570
    296 https://doi.org/10.1038/nbt.1562
    297 rdf:type schema:CreativeWork
    298 sg:pub.10.1038/nbt.1602 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051671503
    299 https://doi.org/10.1038/nbt.1602
    300 rdf:type schema:CreativeWork
    301 sg:pub.10.1038/nbt.1731 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030230970
    302 https://doi.org/10.1038/nbt.1731
    303 rdf:type schema:CreativeWork
    304 sg:pub.10.1038/nbt.1755 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016004947
    305 https://doi.org/10.1038/nbt.1755
    306 rdf:type schema:CreativeWork
    307 sg:pub.10.1038/nbt.1767 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022298591
    308 https://doi.org/10.1038/nbt.1767
    309 rdf:type schema:CreativeWork
    310 sg:pub.10.1038/nbt.1769 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053580569
    311 https://doi.org/10.1038/nbt.1769
    312 rdf:type schema:CreativeWork
    313 sg:pub.10.1038/nbt.1775 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031104364
    314 https://doi.org/10.1038/nbt.1775
    315 rdf:type schema:CreativeWork
    316 sg:pub.10.1038/nbt.1927 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047844983
    317 https://doi.org/10.1038/nbt.1927
    318 rdf:type schema:CreativeWork
    319 sg:pub.10.1038/nbt.1934 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010658010
    320 https://doi.org/10.1038/nbt.1934
    321 rdf:type schema:CreativeWork
    322 sg:pub.10.1038/nbt.1939 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010610351
    323 https://doi.org/10.1038/nbt.1939
    324 rdf:type schema:CreativeWork
    325 sg:pub.10.1038/nbt.1940 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051218365
    326 https://doi.org/10.1038/nbt.1940
    327 rdf:type schema:CreativeWork
    328 sg:pub.10.1038/nbt.2170 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040026920
    329 https://doi.org/10.1038/nbt.2170
    330 rdf:type schema:CreativeWork
    331 sg:pub.10.1038/nbt.2357 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014043446
    332 https://doi.org/10.1038/nbt.2357
    333 rdf:type schema:CreativeWork
    334 sg:pub.10.1038/nbt.2501 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024988605
    335 https://doi.org/10.1038/nbt.2501
    336 rdf:type schema:CreativeWork
    337 sg:pub.10.1038/nbt.2507 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041881936
    338 https://doi.org/10.1038/nbt.2507
    339 rdf:type schema:CreativeWork
    340 sg:pub.10.1038/nbt.2508 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019888616
    341 https://doi.org/10.1038/nbt.2508
    342 rdf:type schema:CreativeWork
    343 sg:pub.10.1038/nbt.2517 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017042091
    344 https://doi.org/10.1038/nbt.2517
    345 rdf:type schema:CreativeWork
    346 sg:pub.10.1038/nbt.2612 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003176820
    347 https://doi.org/10.1038/nbt.2612
    348 rdf:type schema:CreativeWork
    349 sg:pub.10.1038/nbt.2623 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009511624
    350 https://doi.org/10.1038/nbt.2623
    351 rdf:type schema:CreativeWork
    352 sg:pub.10.1038/nbt.2647 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012543463
    353 https://doi.org/10.1038/nbt.2647
    354 rdf:type schema:CreativeWork
    355 sg:pub.10.1038/nbt.2673 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007302590
    356 https://doi.org/10.1038/nbt.2673
    357 rdf:type schema:CreativeWork
    358 sg:pub.10.1038/nbt.2675 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041659759
    359 https://doi.org/10.1038/nbt.2675
    360 rdf:type schema:CreativeWork
    361 sg:pub.10.1038/nbt.2808 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048637524
    362 https://doi.org/10.1038/nbt.2808
    363 rdf:type schema:CreativeWork
    364 sg:pub.10.1038/nbt.2842 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038520013
    365 https://doi.org/10.1038/nbt.2842
    366 rdf:type schema:CreativeWork
    367 sg:pub.10.1038/nbt.2884 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011531387
    368 https://doi.org/10.1038/nbt.2884
    369 rdf:type schema:CreativeWork
    370 sg:pub.10.1038/nbt.2889 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043519930
    371 https://doi.org/10.1038/nbt.2889
    372 rdf:type schema:CreativeWork
    373 sg:pub.10.1038/nbt.2908 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012868720
    374 https://doi.org/10.1038/nbt.2908
    375 rdf:type schema:CreativeWork
    376 sg:pub.10.1038/nbt.2909 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053226125
    377 https://doi.org/10.1038/nbt.2909
    378 rdf:type schema:CreativeWork
    379 sg:pub.10.1038/nbt.2916 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043348902
    380 https://doi.org/10.1038/nbt.2916
    381 rdf:type schema:CreativeWork
    382 sg:pub.10.1038/nbt.3081 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017697957
    383 https://doi.org/10.1038/nbt.3081
    384 rdf:type schema:CreativeWork
    385 sg:pub.10.1038/nbt.3117 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021849416
    386 https://doi.org/10.1038/nbt.3117
    387 rdf:type schema:CreativeWork
    388 sg:pub.10.1038/nbt.3149 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034330725
    389 https://doi.org/10.1038/nbt.3149
    390 rdf:type schema:CreativeWork
    391 sg:pub.10.1038/nbt.3190 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017538548
    392 https://doi.org/10.1038/nbt.3190
    393 rdf:type schema:CreativeWork
    394 sg:pub.10.1038/nbt.3198 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008895789
    395 https://doi.org/10.1038/nbt.3198
    396 rdf:type schema:CreativeWork
    397 sg:pub.10.1038/nbt.3404 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052861805
    398 https://doi.org/10.1038/nbt.3404
    399 rdf:type schema:CreativeWork
    400 sg:pub.10.1038/nbt.3467 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020093829
    401 https://doi.org/10.1038/nbt.3467
    402 rdf:type schema:CreativeWork
    403 sg:pub.10.1038/nbt.3481 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004939292
    404 https://doi.org/10.1038/nbt.3481
    405 rdf:type schema:CreativeWork
    406 sg:pub.10.1038/nbt.3547 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047211077
    407 https://doi.org/10.1038/nbt.3547
    408 rdf:type schema:CreativeWork
    409 sg:pub.10.1038/nbt.3753 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011440933
    410 https://doi.org/10.1038/nbt.3753
    411 rdf:type schema:CreativeWork
    412 sg:pub.10.1038/nbt.3803 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083803971
    413 https://doi.org/10.1038/nbt.3803
    414 rdf:type schema:CreativeWork
    415 sg:pub.10.1038/nbt.3811 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084128647
    416 https://doi.org/10.1038/nbt.3811
    417 rdf:type schema:CreativeWork
    418 sg:pub.10.1038/nbt.3816 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084128652
    419 https://doi.org/10.1038/nbt.3816
    420 rdf:type schema:CreativeWork
    421 sg:pub.10.1038/nbt.3833 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084128666
    422 https://doi.org/10.1038/nbt.3833
    423 rdf:type schema:CreativeWork
    424 sg:pub.10.1038/nbt.3852 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084753472
    425 https://doi.org/10.1038/nbt.3852
    426 rdf:type schema:CreativeWork
    427 sg:pub.10.1038/nbt0714-599 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049485528
    428 https://doi.org/10.1038/nbt0714-599
    429 rdf:type schema:CreativeWork
    430 sg:pub.10.1038/nbt1101-1047 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023451333
    431 https://doi.org/10.1038/nbt1101-1047
    432 rdf:type schema:CreativeWork
    433 sg:pub.10.1038/nbt1201-1173 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033003564
    434 https://doi.org/10.1038/nbt1201-1173
    435 rdf:type schema:CreativeWork
    436 sg:pub.10.1038/nbt1317 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045480104
    437 https://doi.org/10.1038/nbt1317
    438 rdf:type schema:CreativeWork
    439 sg:pub.10.1038/nbt1319 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002154526
    440 https://doi.org/10.1038/nbt1319
    441 rdf:type schema:CreativeWork
    442 sg:pub.10.1038/nbt1353 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026122095
    443 https://doi.org/10.1038/nbt1353
    444 rdf:type schema:CreativeWork
    445 sg:pub.10.1038/nbt1398 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032856466
    446 https://doi.org/10.1038/nbt1398
    447 rdf:type schema:CreativeWork
    448 sg:pub.10.1038/nbt1409 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045837461
    449 https://doi.org/10.1038/nbt1409
    450 rdf:type schema:CreativeWork
    451 sg:pub.10.1038/nbt1410 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048577624
    452 https://doi.org/10.1038/nbt1410
    453 rdf:type schema:CreativeWork
    454 sg:pub.10.1038/nchembio.1793 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042535273
    455 https://doi.org/10.1038/nchembio.1793
    456 rdf:type schema:CreativeWork
    457 sg:pub.10.1038/nchembio832 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040735018
    458 https://doi.org/10.1038/nchembio832
    459 rdf:type schema:CreativeWork
    460 sg:pub.10.1038/ncomms13330 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024993788
    461 https://doi.org/10.1038/ncomms13330
    462 rdf:type schema:CreativeWork
    463 sg:pub.10.1038/ncomms15790 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085880702
    464 https://doi.org/10.1038/ncomms15790
    465 rdf:type schema:CreativeWork
    466 sg:pub.10.1038/nm.3793 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052797737
    467 https://doi.org/10.1038/nm.3793
    468 rdf:type schema:CreativeWork
    469 sg:pub.10.1038/nm996 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040467981
    470 https://doi.org/10.1038/nm996
    471 rdf:type schema:CreativeWork
    472 sg:pub.10.1038/nmeth.1670 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043918422
    473 https://doi.org/10.1038/nmeth.1670
    474 rdf:type schema:CreativeWork
    475 sg:pub.10.1038/nmeth.2364 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015862962
    476 https://doi.org/10.1038/nmeth.2364
    477 rdf:type schema:CreativeWork
    478 sg:pub.10.1038/nmeth.2366 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040994508
    479 https://doi.org/10.1038/nmeth.2366
    480 rdf:type schema:CreativeWork
    481 sg:pub.10.1038/nmeth.2521 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025077524
    482 https://doi.org/10.1038/nmeth.2521
    483 rdf:type schema:CreativeWork
    484 sg:pub.10.1038/nmeth.2598 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049500416
    485 https://doi.org/10.1038/nmeth.2598
    486 rdf:type schema:CreativeWork
    487 sg:pub.10.1038/nmeth.2600 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024354143
    488 https://doi.org/10.1038/nmeth.2600
    489 rdf:type schema:CreativeWork
    490 sg:pub.10.1038/nmeth.2649 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008703730
    491 https://doi.org/10.1038/nmeth.2649
    492 rdf:type schema:CreativeWork
    493 sg:pub.10.1038/nmeth.2681 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028304735
    494 https://doi.org/10.1038/nmeth.2681
    495 rdf:type schema:CreativeWork
    496 sg:pub.10.1038/nmeth.2845 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002278800
    497 https://doi.org/10.1038/nmeth.2845
    498 rdf:type schema:CreativeWork
    499 sg:pub.10.1038/nmeth.3312 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008897838
    500 https://doi.org/10.1038/nmeth.3312
    501 rdf:type schema:CreativeWork
    502 sg:pub.10.1038/nmeth.3993 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016047103
    503 https://doi.org/10.1038/nmeth.3993
    504 rdf:type schema:CreativeWork
    505 sg:pub.10.1038/nmeth.4027 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038829252
    506 https://doi.org/10.1038/nmeth.4027
    507 rdf:type schema:CreativeWork
    508 sg:pub.10.1038/nmeth.4038 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030846996
    509 https://doi.org/10.1038/nmeth.4038
    510 rdf:type schema:CreativeWork
    511 sg:pub.10.1038/nmeth.4327 schema:sameAs https://app.dimensions.ai/details/publication/pub.1085864346
    512 https://doi.org/10.1038/nmeth.4327
    513 rdf:type schema:CreativeWork
    514 sg:pub.10.1038/nmeth0508-374 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021094033
    515 https://doi.org/10.1038/nmeth0508-374
    516 rdf:type schema:CreativeWork
    517 sg:pub.10.1038/nprot.2011.431 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020679703
    518 https://doi.org/10.1038/nprot.2011.431
    519 rdf:type schema:CreativeWork
    520 sg:pub.10.1038/nprot.2013.132 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009361018
    521 https://doi.org/10.1038/nprot.2013.132
    522 rdf:type schema:CreativeWork
    523 sg:pub.10.1038/nprot.2013.143 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016534425
    524 https://doi.org/10.1038/nprot.2013.143
    525 rdf:type schema:CreativeWork
    526 sg:pub.10.1038/nrc3179 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052351170
    527 https://doi.org/10.1038/nrc3179
    528 rdf:type schema:CreativeWork
    529 sg:pub.10.1038/nrd1087 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040287926
    530 https://doi.org/10.1038/nrd1087
    531 rdf:type schema:CreativeWork
    532 sg:pub.10.1038/nrg2380 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041270694
    533 https://doi.org/10.1038/nrg2380
    534 rdf:type schema:CreativeWork
    535 sg:pub.10.1038/nrg2842 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018939216
    536 https://doi.org/10.1038/nrg2842
    537 rdf:type schema:CreativeWork
    538 sg:pub.10.1038/nrm1202 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010441359
    539 https://doi.org/10.1038/nrm1202
    540 rdf:type schema:CreativeWork
    541 sg:pub.10.1038/nrm2058 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005655334
    542 https://doi.org/10.1038/nrm2058
    543 rdf:type schema:CreativeWork
    544 sg:pub.10.1038/nrm3486 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050461034
    545 https://doi.org/10.1038/nrm3486
    546 rdf:type schema:CreativeWork
    547 sg:pub.10.1038/nrmicro2577 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020345829
    548 https://doi.org/10.1038/nrmicro2577
    549 rdf:type schema:CreativeWork
    550 sg:pub.10.1038/nrmicro3569 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010036058
    551 https://doi.org/10.1038/nrmicro3569
    552 rdf:type schema:CreativeWork
    553 sg:pub.10.1038/nrneurol.2012.263 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005735277
    554 https://doi.org/10.1038/nrneurol.2012.263
    555 rdf:type schema:CreativeWork
    556 sg:pub.10.1038/nsmb.1744 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002558962
    557 https://doi.org/10.1038/nsmb.1744
    558 rdf:type schema:CreativeWork
    559 sg:pub.10.1038/nsmb.2019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011829375
    560 https://doi.org/10.1038/nsmb.2019
    561 rdf:type schema:CreativeWork
    562 sg:pub.10.1038/nsmb.2879 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010082311
    563 https://doi.org/10.1038/nsmb.2879
    564 rdf:type schema:CreativeWork
    565 sg:pub.10.1038/nsmb1047 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005930818
    566 https://doi.org/10.1038/nsmb1047
    567 rdf:type schema:CreativeWork
    568 sg:pub.10.1038/nsmb1094 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015513776
    569 https://doi.org/10.1038/nsmb1094
    570 rdf:type schema:CreativeWork
    571 sg:pub.10.1038/s41467-017-00175-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090780642
    572 https://doi.org/10.1038/s41467-017-00175-6
    573 rdf:type schema:CreativeWork
    574 sg:pub.10.1038/sj.gt.3300965 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048788770
    575 https://doi.org/10.1038/sj.gt.3300965
    576 rdf:type schema:CreativeWork
    577 sg:pub.10.1038/sj.onc.1208304 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036710331
    578 https://doi.org/10.1038/sj.onc.1208304
    579 rdf:type schema:CreativeWork
    580 sg:pub.10.1038/srep10777 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049485171
    581 https://doi.org/10.1038/srep10777
    582 rdf:type schema:CreativeWork
    583 sg:pub.10.1186/1471-2105-12-15 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002905857
    584 https://doi.org/10.1186/1471-2105-12-15
    585 rdf:type schema:CreativeWork
    586 sg:pub.10.1186/1471-2105-12-152 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031107821
    587 https://doi.org/10.1186/1471-2105-12-152
    588 rdf:type schema:CreativeWork
    589 sg:pub.10.1186/1471-2199-15-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018784555
    590 https://doi.org/10.1186/1471-2199-15-6
    591 rdf:type schema:CreativeWork
    592 sg:pub.10.1186/gb-2008-9-6-229 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021664284
    593 https://doi.org/10.1186/gb-2008-9-6-229
    594 rdf:type schema:CreativeWork
    595 sg:pub.10.1186/gb-2011-12-11-r112 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027516867
    596 https://doi.org/10.1186/gb-2011-12-11-r112
    597 rdf:type schema:CreativeWork
    598 sg:pub.10.1186/s13059-014-0417-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1025106002
    599 https://doi.org/10.1186/s13059-014-0417-z
    600 rdf:type schema:CreativeWork
    601 sg:pub.10.1186/s13059-015-0584-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024223648
    602 https://doi.org/10.1186/s13059-015-0584-6
    603 rdf:type schema:CreativeWork
    604 sg:pub.10.1532/ijh97.06032 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041769571
    605 https://doi.org/10.1532/ijh97.06032
    606 rdf:type schema:CreativeWork
    607 sg:pub.10.1631/jzus.b1200042 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038506352
    608 https://doi.org/10.1631/jzus.b1200042
    609 rdf:type schema:CreativeWork
    610 grid-institutes:grid.38142.3c schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...