Genome Editing Of A Rosa Locus Using Zinc-Finger Nucleases


Ontology type: sgo:Patent     


Patent Info

DATE

2013-10-16T00:00

AUTHORS

CUI XIAOXIA , DAVIS GREGORY , GREGORY PHILIP D , HOLMES MICHAEL C , WEINSTEIN EDWARD J

ABSTRACT

Disclosed herein are methods and compositions for genome editing of a Rosa locus, using fusion proteins comprising a zinc-finger protein and a cleavage domain or cleavage half-domain. Polynucleotides encoding said fusion proteins are also provided, as are cells comprising said polynucleotides and fusion proteins.

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