Methods Of Deriving Differentiated Cells From Stem Cells


Ontology type: sgo:Patent     


Patent Info

DATE

2011-09-28T00:00

AUTHORS

TUROVETS, NIKOLAY , AGAPOVA, LARISA , SEMECHKIN, ANDREY , JANUS, JEFFREY, D.

ABSTRACT

The present invention provides a method of generating definitive endoderm, mesoderm, or ectoderm cells. The method includes culturing embryonic stem cells, parthenogenetic cells, or induced pluripotent stem cells in the presence of a demethylation agent, a histone deacetylase inhibitor, or a combination thereof, and thereafter, culturing the stem cells in the absence of the agent or combination of agents, to produce definitive endoderm cells, mesoderm, or ectoderm cells. More... »

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