Alternative nucleotides for improved targeted nucleotide exchange


Ontology type: sgo:Patent     


Patent Info

DATE

2011-06-15T00:00

AUTHORS

BUNDOCK, PAUL , DE BOTH, MICHIEL THEODOOR JAN , Hogers, René Cornelis Josephus

ABSTRACT

A method and oligonucleotides for targeted nucleotide exchange of a duplex DNA sequence, wherein the donor oligonucleotide contains at least one modified nucleotide having a higher binding affinity compared to naturally occurring A, C, T or G and/or binds stronger to a nucleotide in an opposite position in the first DNA sequence as compared to a naturally occurring nucleotide complementary to the nucleotide in the opposite position in the first DNA sequence. More... »

Related SciGraph Publications

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/2620", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "name": "BUNDOCK, PAUL", 
        "type": "Person"
      }, 
      {
        "name": "DE BOTH, MICHIEL THEODOOR JAN", 
        "type": "Person"
      }, 
      {
        "name": "Hogers, Ren\u00e9 Cornelis Josephus", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/s0890-8508(03)00062-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011510168"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0890-8508(03)00062-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011510168"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1399-3054.1962.tb08052.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023703429"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1074-5521(02)00236-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024176188"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1074-5521(02)00236-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024176188"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/gkg820", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026585102"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jsre.1996.0236", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032357905"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/28.20.3904", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038155368"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.gt.3302511", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045259912", 
          "https://doi.org/10.1038/sj.gt.3302511"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.gt.3302511", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045259912", 
          "https://doi.org/10.1038/sj.gt.3302511"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2307/2437836", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069931886"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2011-06-15T00:00", 
    "description": "

A method and oligonucleotides for targeted nucleotide exchange of a duplex DNA sequence, wherein the donor oligonucleotide contains at least one modified nucleotide having a higher binding affinity compared to naturally occurring A, C, T or G and/or binds stronger to a nucleotide in an opposite position in the first DNA sequence as compared to a naturally occurring nucleotide complementary to the nucleotide in the opposite position in the first DNA sequence.\n

", "id": "sg:patent.EP-2333115-A1", "keywords": [ "alternative", "nucleotide exchange", "method", "oligonucleotides", "duplex DNA", "wherein", "modified nucleotide", "high binding affinity", "nucleotide", "sequence" ], "name": "Alternative nucleotides for improved targeted nucleotide exchange", "recipient": [ { "id": "https://www.grid.ac/institutes/grid.425600.5", "type": "Organization" } ], "sameAs": [ "https://app.dimensions.ai/details/patent/EP-2333115-A1" ], "sdDataset": "patents", "sdDatePublished": "2019-04-18T10:07", "sdLicense": "https://scigraph.springernature.com/explorer/license/", "sdPublisher": { "name": "Springer Nature - SN SciGraph project", "type": "Organization" }, "sdSource": "s3://com-uberresearch-data-patents-target-20190320-rc/data/sn-export/402f166718b70575fb5d4ffe01f064d1/0000100128-0000352499/json_export_00206.jsonl", "type": "Patent" } ]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/patent.EP-2333115-A1'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/patent.EP-2333115-A1'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/patent.EP-2333115-A1'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/patent.EP-2333115-A1'


 

This table displays all metadata directly associated to this object as RDF triples.

65 TRIPLES      15 PREDICATES      32 URIs      18 LITERALS      2 BLANK NODES

Subject Predicate Object
1 sg:patent.EP-2333115-A1 schema:about anzsrc-for:2620
2 schema:author N79080105f3cf4b8f890a4fbf710e1747
3 schema:citation sg:pub.10.1038/sj.gt.3302511
4 https://doi.org/10.1006/jsre.1996.0236
5 https://doi.org/10.1016/s0890-8508(03)00062-8
6 https://doi.org/10.1016/s1074-5521(02)00236-3
7 https://doi.org/10.1093/nar/28.20.3904
8 https://doi.org/10.1093/nar/gkg820
9 https://doi.org/10.1111/j.1399-3054.1962.tb08052.x
10 https://doi.org/10.2307/2437836
11 schema:datePublished 2011-06-15T00:00
12 schema:description <p num="pa01">A method and oligonucleotides for targeted nucleotide exchange of a duplex DNA sequence, wherein the donor oligonucleotide contains at least one modified nucleotide having a higher binding affinity compared to naturally occurring A, C, T or G and/or binds stronger to a nucleotide in an opposite position in the first DNA sequence as compared to a naturally occurring nucleotide complementary to the nucleotide in the opposite position in the first DNA sequence. <img id="iaf01" file="imgaf001.tif" wi="83" he="91" img-content="drawing" img-format="tif"/></p>
13 schema:keywords alternative
14 duplex DNA
15 high binding affinity
16 method
17 modified nucleotide
18 nucleotide
19 nucleotide exchange
20 oligonucleotides
21 sequence
22 wherein
23 schema:name Alternative nucleotides for improved targeted nucleotide exchange
24 schema:recipient https://www.grid.ac/institutes/grid.425600.5
25 schema:sameAs https://app.dimensions.ai/details/patent/EP-2333115-A1
26 schema:sdDatePublished 2019-04-18T10:07
27 schema:sdLicense https://scigraph.springernature.com/explorer/license/
28 schema:sdPublisher N07dbf1508fc842928e8fec471dd68f78
29 sgo:license sg:explorer/license/
30 sgo:sdDataset patents
31 rdf:type sgo:Patent
32 N07dbf1508fc842928e8fec471dd68f78 schema:name Springer Nature - SN SciGraph project
33 rdf:type schema:Organization
34 N2e377b17067a4ce3968ecd51348ef6a8 rdf:first Nc5a24d5909174769964529963a145b8c
35 rdf:rest N43ec085eb9904a86b590c6ade1e205fd
36 N43ec085eb9904a86b590c6ade1e205fd rdf:first N9c696a852cce43e4b0b1a337b1cb7b49
37 rdf:rest rdf:nil
38 N777e047647b44a2eb20a408a05611fa2 schema:name BUNDOCK, PAUL
39 rdf:type schema:Person
40 N79080105f3cf4b8f890a4fbf710e1747 rdf:first N777e047647b44a2eb20a408a05611fa2
41 rdf:rest N2e377b17067a4ce3968ecd51348ef6a8
42 N9c696a852cce43e4b0b1a337b1cb7b49 schema:name Hogers, René Cornelis Josephus
43 rdf:type schema:Person
44 Nc5a24d5909174769964529963a145b8c schema:name DE BOTH, MICHIEL THEODOOR JAN
45 rdf:type schema:Person
46 anzsrc-for:2620 schema:inDefinedTermSet anzsrc-for:
47 rdf:type schema:DefinedTerm
48 sg:pub.10.1038/sj.gt.3302511 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045259912
49 https://doi.org/10.1038/sj.gt.3302511
50 rdf:type schema:CreativeWork
51 https://doi.org/10.1006/jsre.1996.0236 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032357905
52 rdf:type schema:CreativeWork
53 https://doi.org/10.1016/s0890-8508(03)00062-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011510168
54 rdf:type schema:CreativeWork
55 https://doi.org/10.1016/s1074-5521(02)00236-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024176188
56 rdf:type schema:CreativeWork
57 https://doi.org/10.1093/nar/28.20.3904 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038155368
58 rdf:type schema:CreativeWork
59 https://doi.org/10.1093/nar/gkg820 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026585102
60 rdf:type schema:CreativeWork
61 https://doi.org/10.1111/j.1399-3054.1962.tb08052.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1023703429
62 rdf:type schema:CreativeWork
63 https://doi.org/10.2307/2437836 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069931886
64 rdf:type schema:CreativeWork
65 https://www.grid.ac/institutes/grid.425600.5 schema:Organization
 




Preview window. Press ESC to close (or click here)


...