Ontology type: sgo:Patent
2011-04-06T00:00
AUTHORSBURNETT JOHN C , CHEN HORNG H , LISY ONDREJ
ABSTRACTMaterials and methods related to chimeric polypeptides containing the amino acid sequence of CNP and the C-terminal sequence of DNP. The polypeptides are natriuretic and diuretic, GFR enhancing, cardiac unloading, renin inhibiting and less hypotensive when compared to BNP. The polypeptides also inhibit cardiac fibroblast proliferation.
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