Chimeric Natriuretic Polypeptides And Methods For Inhibiting Cardiac Remodeling


Ontology type: sgo:Patent     


Patent Info

DATE

2011-04-06T00:00

AUTHORS

BURNETT JOHN C , CHEN HORNG H , LISY ONDREJ

ABSTRACT

Materials and methods related to chimeric polypeptides containing the amino acid sequence of CNP and the C-terminal sequence of DNP. The polypeptides are natriuretic and diuretic, GFR enhancing, cardiac unloading, renin inhibiting and less hypotensive when compared to BNP. The polypeptides also inhibit cardiac fibroblast proliferation.

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "name": "BURNETT JOHN C", 
        "type": "Person"
      }, 
      {
        "name": "CHEN HORNG H", 
        "type": "Person"
      }, 
      {
        "name": "LISY ONDREJ", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s11897-010-0016-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022530445", 
          "https://doi.org/10.1007/s11897-010-0016-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10741-005-4635-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052930165", 
          "https://doi.org/10.1007/s10741-005-4635-z"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2011-04-06T00:00", 
    "description": "

Materials and methods related to chimeric polypeptides containing the amino acid sequence of CNP and the C-terminal sequence of DNP. The polypeptides are natriuretic and diuretic, GFR enhancing, cardiac unloading, renin inhibiting and less hypotensive when compared to BNP. The polypeptides also inhibit cardiac fibroblast proliferation.

", "id": "sg:patent.EP-2303305-A2", "name": "CHIMERIC NATRIURETIC POLYPEPTIDES AND METHODS FOR INHIBITING CARDIAC REMODELING", "recipient": [ { "id": "http://www.grid.ac/institutes/grid.417467.7", "type": "Organization" } ], "sameAs": [ "https://app.dimensions.ai/details/patent/EP-2303305-A2" ], "sdDataset": "patents", "sdDatePublished": "2022-10-01T07:03", "sdLicense": "https://scigraph.springernature.com/explorer/license/", "sdPublisher": { "name": "Springer Nature - SN SciGraph project", "type": "Organization" }, "sdSource": "s3://com-springernature-scigraph/baseset/20221001/entities/gbq_results/patent/patent_11.jsonl", "type": "Patent" } ]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/patent.EP-2303305-A2'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/patent.EP-2303305-A2'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/patent.EP-2303305-A2'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/patent.EP-2303305-A2'


 

This table displays all metadata directly associated to this object as RDF triples.

41 TRIPLES      14 PREDICATES      17 URIs      8 LITERALS      2 BLANK NODES

Subject Predicate Object
1 sg:patent.EP-2303305-A2 schema:about anzsrc-for:11
2 anzsrc-for:1102
3 schema:author Nc57c7941e19d4b24abbcaab459886db2
4 schema:citation sg:pub.10.1007/s10741-005-4635-z
5 sg:pub.10.1007/s11897-010-0016-6
6 schema:datePublished 2011-04-06T00:00
7 schema:description <p>Materials and methods related to chimeric polypeptides containing the amino acid sequence of CNP and the C-terminal sequence of DNP. The polypeptides are natriuretic and diuretic, GFR enhancing, cardiac unloading, renin inhibiting and less hypotensive when compared to BNP. The polypeptides also inhibit cardiac fibroblast proliferation.</p>
8 schema:name CHIMERIC NATRIURETIC POLYPEPTIDES AND METHODS FOR INHIBITING CARDIAC REMODELING
9 schema:recipient grid-institutes:grid.417467.7
10 schema:sameAs https://app.dimensions.ai/details/patent/EP-2303305-A2
11 schema:sdDatePublished 2022-10-01T07:03
12 schema:sdLicense https://scigraph.springernature.com/explorer/license/
13 schema:sdPublisher N193cf1c1cb1d4fe1ac40343bbd3b93c8
14 sgo:license sg:explorer/license/
15 sgo:sdDataset patents
16 rdf:type sgo:Patent
17 N193cf1c1cb1d4fe1ac40343bbd3b93c8 schema:name Springer Nature - SN SciGraph project
18 rdf:type schema:Organization
19 N6fa21f0843e84a66b8888ca6b1633f17 schema:name CHEN HORNG H
20 rdf:type schema:Person
21 Na9972721e7124c15a1bcfd36a6bde2da schema:name LISY ONDREJ
22 rdf:type schema:Person
23 Nc57c7941e19d4b24abbcaab459886db2 rdf:first Nf145ee36815b4111b7f1aae5fe3d6278
24 rdf:rest Nc6e93a68039b4759b9e6b2cd1e697ff1
25 Nc6e93a68039b4759b9e6b2cd1e697ff1 rdf:first N6fa21f0843e84a66b8888ca6b1633f17
26 rdf:rest Ne1e14efdfba040f2b9159b525dfd88d8
27 Ne1e14efdfba040f2b9159b525dfd88d8 rdf:first Na9972721e7124c15a1bcfd36a6bde2da
28 rdf:rest rdf:nil
29 Nf145ee36815b4111b7f1aae5fe3d6278 schema:name BURNETT JOHN C
30 rdf:type schema:Person
31 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
32 rdf:type schema:DefinedTerm
33 anzsrc-for:1102 schema:inDefinedTermSet anzsrc-for:
34 rdf:type schema:DefinedTerm
35 sg:pub.10.1007/s10741-005-4635-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1052930165
36 https://doi.org/10.1007/s10741-005-4635-z
37 rdf:type schema:CreativeWork
38 sg:pub.10.1007/s11897-010-0016-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022530445
39 https://doi.org/10.1007/s11897-010-0016-6
40 rdf:type schema:CreativeWork
41 grid-institutes:grid.417467.7 schema:Organization
 




Preview window. Press ESC to close (or click here)


...