Multicistronic siRNA constructs to inhibit tumors


Ontology type: sgo:Patent     


Patent Info

DATE

2010-05-26T00:00

AUTHORS

GONDI, CHRISTOPHER S. , LAKKA, SAJANI S. , RAO, JASTI S.

ABSTRACT

Multicistronic short interfering RNA constructs targeting in various combinations a human urokinase-type plasminogen activator receptor (uPAR), human utokinase-type plasminogen activator (uPA), human matrix metalloprotease 9 (MMP-9) and cathepsin B (CB) inhibit tumors.

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