GENERATION OF LIBRARY OF SOLUBLE RANDOM POLYPEPTIDES LINKED TO mRNA


Ontology type: sgo:Patent     


Patent Info

DATE

N/A

AUTHORS

WILLIAMS, RICHARD, B.

ABSTRACT

Methods and compositions are provided for producing libraries of soluble random polypeptides. In the methods, the fraction of hydrophilic residues in the polypeptide is controlled so as to maintain the solubility of the polypeptide constructs.

Related SciGraph Publications

  • 1997-10. Functional rapidly folding proteins from simplified amino acid sequences in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2001-04. Functional proteins from a random-sequence library in NATURE
  • 1995-10. Cooperatively folded proteins in random sequence libraries in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/2358", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "name": "WILLIAMS, RICHARD, B.", 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "https://doi.org/10.1016/0014-5793(96)00123-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001312528"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.91.6.2146", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004943155"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/35070613", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011729333", 
              "https://doi.org/10.1038/35070613"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.chembiol.2004.04.006", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011892149"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nsb1095-856", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018044021", 
              "https://doi.org/10.1038/nsb1095-856"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1006/jmbi.2000.3571", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033737636"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nsb1097-805", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040994478", 
              "https://doi.org/10.1038/nsb1097-805"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "description": "

    Methods and compositions are provided for producing libraries of soluble random polypeptides. In the methods, the fraction of hydrophilic residues in the polypeptide is controlled so as to maintain the solubility of the polypeptide constructs.

    ", "id": "sg:patent.EP-2118344-A2", "keywords": [ "generation", "polypeptide", "method", "composition", "library", "fraction", "residue", "solubility" ], "name": "GENERATION OF LIBRARY OF SOLUBLE RANDOM POLYPEPTIDES LINKED TO mRNA", "sameAs": [ "https://app.dimensions.ai/details/patent/EP-2118344-A2" ], "sdDataset": "patents", "sdDatePublished": "2019-03-07T15:34", "sdLicense": "https://scigraph.springernature.com/explorer/license/", "sdPublisher": { "name": "Springer Nature - SN SciGraph project", "type": "Organization" }, "sdSource": "s3://com.uberresearch.data.dev.patents-pipeline/full_run_10/sn-export/5eb3e5a348d7f117b22cc85fb0b02730/0000100128-0000348334/json_export_83943d3a.jsonl", "type": "Patent" } ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/patent.EP-2118344-A2'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/patent.EP-2118344-A2'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/patent.EP-2118344-A2'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/patent.EP-2118344-A2'


     

    This table displays all metadata directly associated to this object as RDF triples.

    51 TRIPLES      13 PREDICATES      27 URIs      15 LITERALS      2 BLANK NODES

    Subject Predicate Object
    1 sg:patent.EP-2118344-A2 schema:about anzsrc-for:2358
    2 schema:author N9d48006a9dac47a5b59e5c284c9a0a63
    3 schema:citation sg:pub.10.1038/35070613
    4 sg:pub.10.1038/nsb1095-856
    5 sg:pub.10.1038/nsb1097-805
    6 https://doi.org/10.1006/jmbi.2000.3571
    7 https://doi.org/10.1016/0014-5793(96)00123-8
    8 https://doi.org/10.1016/j.chembiol.2004.04.006
    9 https://doi.org/10.1073/pnas.91.6.2146
    10 schema:description <p>Methods and compositions are provided for producing libraries of soluble random polypeptides. In the methods, the fraction of hydrophilic residues in the polypeptide is controlled so as to maintain the solubility of the polypeptide constructs.</p>
    11 schema:keywords composition
    12 fraction
    13 generation
    14 library
    15 method
    16 polypeptide
    17 residue
    18 solubility
    19 schema:name GENERATION OF LIBRARY OF SOLUBLE RANDOM POLYPEPTIDES LINKED TO mRNA
    20 schema:sameAs https://app.dimensions.ai/details/patent/EP-2118344-A2
    21 schema:sdDatePublished 2019-03-07T15:34
    22 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    23 schema:sdPublisher N91aafe9e3bc241d59236bf661df6d792
    24 sgo:license sg:explorer/license/
    25 sgo:sdDataset patents
    26 rdf:type sgo:Patent
    27 N548030699c0c4f44b103055b4029b9bc schema:name WILLIAMS, RICHARD, B.
    28 rdf:type schema:Person
    29 N91aafe9e3bc241d59236bf661df6d792 schema:name Springer Nature - SN SciGraph project
    30 rdf:type schema:Organization
    31 N9d48006a9dac47a5b59e5c284c9a0a63 rdf:first N548030699c0c4f44b103055b4029b9bc
    32 rdf:rest rdf:nil
    33 anzsrc-for:2358 schema:inDefinedTermSet anzsrc-for:
    34 rdf:type schema:DefinedTerm
    35 sg:pub.10.1038/35070613 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011729333
    36 https://doi.org/10.1038/35070613
    37 rdf:type schema:CreativeWork
    38 sg:pub.10.1038/nsb1095-856 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018044021
    39 https://doi.org/10.1038/nsb1095-856
    40 rdf:type schema:CreativeWork
    41 sg:pub.10.1038/nsb1097-805 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040994478
    42 https://doi.org/10.1038/nsb1097-805
    43 rdf:type schema:CreativeWork
    44 https://doi.org/10.1006/jmbi.2000.3571 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033737636
    45 rdf:type schema:CreativeWork
    46 https://doi.org/10.1016/0014-5793(96)00123-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001312528
    47 rdf:type schema:CreativeWork
    48 https://doi.org/10.1016/j.chembiol.2004.04.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011892149
    49 rdf:type schema:CreativeWork
    50 https://doi.org/10.1073/pnas.91.6.2146 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004943155
    51 rdf:type schema:CreativeWork
     




    Preview window. Press ESC to close (or click here)


    ...