Dna Sensor


Ontology type: sgo:Patent     


Patent Info

DATE

N/A

AUTHORS

KAWARADA HIROSHI

ABSTRACT

A DNA sensor is provided which is capable of identifying unknown DNA with enhanced detection sensitivity of the hybridization. A p-channel field-effect transistor having an electrolyte solution gate 8 and having as a p-channel 5 a diamond surface 2 which contains a mixture of at least a hydrogen-terminated surface and a surface terminated with an amino group or a molecule with an amino group is configured along with a probe DNA 11 constituted of a single-stranded DNA with known nucleotide sequence which is directly immobilized by a linker to the diamond surface 2 and with a target DNA constituted of an unknown single-stranded DNA which is dropped on the diamond surface 2. When the target DNA is in complementary relationship to the probe DNA 11, negative electric charge of the phosphate group of a double-stranded DNA produced by the hybridization of the probe DNA 11 with the target DNA both constituted of a single-stranded DNA is doubled, thereby resulting in increase of the hole density in the p-channel and shift of the threshold voltage of the p-channel field effect transistor toward positive direction. By detecting this shift of the threshold voltage toward positive direction, an identification can be made on whether or not the target DNA is in complementary relationship to the probe DNA 11. More... »

Related SciGraph Publications

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/2471", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "name": "KAWARADA HIROSHI", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1002/pssa.200303809", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031940391"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nmat779", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050843407", 
          "https://doi.org/10.1038/nmat779"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1143/jjap.43.l1137", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1063073357"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "description": "

A DNA sensor is provided which is capable of identifying unknown DNA with enhanced detection sensitivity of the hybridization. A p-channel field-effect transistor having an electrolyte solution gate 8 and having as a p-channel 5 a diamond surface 2 which contains a mixture of at least a hydrogen-terminated surface and a surface terminated with an amino group or a molecule with an amino group is configured along with a probe DNA 11 constituted of a single-stranded DNA with known nucleotide sequence which is directly immobilized by a linker to the diamond surface 2 and with a target DNA constituted of an unknown single-stranded DNA which is dropped on the diamond surface 2. When the target DNA is in complementary relationship to the probe DNA 11, negative electric charge of the phosphate group of a double-stranded DNA produced by the hybridization of the probe DNA 11 with the target DNA both constituted of a single-stranded DNA is doubled, thereby resulting in increase of the hole density in the p-channel and shift of the threshold voltage of the p-channel field effect transistor toward positive direction. By detecting this shift of the threshold voltage toward positive direction, an identification can be made on whether or not the target DNA is in complementary relationship to the probe DNA 11.

", "id": "sg:patent.EP-1788383-A4", "keywords": [ "sensor", "DNA", "detection sensitivity", "hybridization", "field effect transistor", "electrolyte solution", "channel", "diamond", "mixture", "hydrogen", "surface", "amino group", "molecule", "probe", "single-stranded DNA", "nucleotide", "linker", "target DNA", "electric charge", "phosphate group", "density", "shift", "threshold voltage" ], "name": "DNA SENSOR", "recipient": [ { "id": "https://www.grid.ac/institutes/grid.419082.6", "type": "Organization" } ], "sameAs": [ "https://app.dimensions.ai/details/patent/EP-1788383-A4" ], "sdDataset": "patents", "sdDatePublished": "2019-03-07T15:30", "sdLicense": "https://scigraph.springernature.com/explorer/license/", "sdPublisher": { "name": "Springer Nature - SN SciGraph project", "type": "Organization" }, "sdSource": "s3://com.uberresearch.data.dev.patents-pipeline/full_run_10/sn-export/5eb3e5a348d7f117b22cc85fb0b02730/0000100128-0000348334/json_export_0782263a.jsonl", "type": "Patent" } ]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/patent.EP-1788383-A4'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/patent.EP-1788383-A4'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/patent.EP-1788383-A4'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/patent.EP-1788383-A4'


 

This table displays all metadata directly associated to this object as RDF triples.

54 TRIPLES      14 PREDICATES      39 URIs      30 LITERALS      2 BLANK NODES

Subject Predicate Object
1 sg:patent.EP-1788383-A4 schema:about anzsrc-for:2471
2 schema:author Nd250d6859d304794b81f33f8206362da
3 schema:citation sg:pub.10.1038/nmat779
4 https://doi.org/10.1002/pssa.200303809
5 https://doi.org/10.1143/jjap.43.l1137
6 schema:description <p num="pa01">A DNA sensor is provided which is capable of identifying unknown DNA with enhanced detection sensitivity of the hybridization. A p-channel field-effect transistor having an electrolyte solution gate 8 and having as a p-channel 5 a diamond surface 2 which contains a mixture of at least a hydrogen-terminated surface and a surface terminated with an amino group or a molecule with an amino group is configured along with a probe DNA 11 constituted of a single-stranded DNA with known nucleotide sequence which is directly immobilized by a linker to the diamond surface 2 and with a target DNA constituted of an unknown single-stranded DNA which is dropped on the diamond surface 2. When the target DNA is in complementary relationship to the probe DNA 11, negative electric charge of the phosphate group of a double-stranded DNA produced by the hybridization of the probe DNA 11 with the target DNA both constituted of a single-stranded DNA is doubled, thereby resulting in increase of the hole density in the p-channel and shift of the threshold voltage of the p-channel field effect transistor toward positive direction. By detecting this shift of the threshold voltage toward positive direction, an identification can be made on whether or not the target DNA is in complementary relationship to the probe DNA 11.<img id="iaf01" file="imgaf001.tif" wi="78" he="82" img-content="drawing" img-format="tif"/></p>
7 schema:keywords DNA
8 amino group
9 channel
10 density
11 detection sensitivity
12 diamond
13 electric charge
14 electrolyte solution
15 field effect transistor
16 hybridization
17 hydrogen
18 linker
19 mixture
20 molecule
21 nucleotide
22 phosphate group
23 probe
24 sensor
25 shift
26 single-stranded DNA
27 surface
28 target DNA
29 threshold voltage
30 schema:name DNA SENSOR
31 schema:recipient https://www.grid.ac/institutes/grid.419082.6
32 schema:sameAs https://app.dimensions.ai/details/patent/EP-1788383-A4
33 schema:sdDatePublished 2019-03-07T15:30
34 schema:sdLicense https://scigraph.springernature.com/explorer/license/
35 schema:sdPublisher Nec90a525141044a680408a642de3a187
36 sgo:license sg:explorer/license/
37 sgo:sdDataset patents
38 rdf:type sgo:Patent
39 N03343074cf2541d4a81f81716caeede1 schema:name KAWARADA HIROSHI
40 rdf:type schema:Person
41 Nd250d6859d304794b81f33f8206362da rdf:first N03343074cf2541d4a81f81716caeede1
42 rdf:rest rdf:nil
43 Nec90a525141044a680408a642de3a187 schema:name Springer Nature - SN SciGraph project
44 rdf:type schema:Organization
45 anzsrc-for:2471 schema:inDefinedTermSet anzsrc-for:
46 rdf:type schema:DefinedTerm
47 sg:pub.10.1038/nmat779 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050843407
48 https://doi.org/10.1038/nmat779
49 rdf:type schema:CreativeWork
50 https://doi.org/10.1002/pssa.200303809 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031940391
51 rdf:type schema:CreativeWork
52 https://doi.org/10.1143/jjap.43.l1137 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063073357
53 rdf:type schema:CreativeWork
54 https://www.grid.ac/institutes/grid.419082.6 schema:Organization
 




Preview window. Press ESC to close (or click here)


...