Quinazoline-4-one AMPA antagonists for the treatment of dyskinesias associated with dopamine agonist therapy


Ontology type: sgo:Patent     


Patent Info

DATE

1999-03-10T00:00

AUTHORS

CHENARD, BERTRAND LEO , GREENAMYRE, JOHN TIMOTHY , MENNITI, FRANK SAMUEL , WELCH, WILLARD MCKOWAN, JR.

ABSTRACT

The invention relates to a method of treating dyskinesias associated with dopamine agonist therapy in a mammal which comprises administering to said mammal an effective amount of an antagonist of the AMPA receptor. Dopamine agonist therapy, as referred to in the present invention, is generally used in the treatment of a central nervous system disorder such as Parkinson's disease. More... »

Related SciGraph Publications

  • 1991-09. Synergism of the AMPA-antagonist NBQX and the NMDA-antagonist CPP with L-Dopa in models of Parkinson's disease in JOURNAL OF NEURAL TRANSMISSION: PARKINSON'S DISEASE A AND DEMENTIA SECTION
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