High Level Inducible Expression Of Heterologous Genes.


Ontology type: sgo:Patent     


Patent Info

DATE

1989-12-22T00:00

AUTHORS

KAUFMAN RANDAL J , ISRAEL DAVID

ABSTRACT

A method for producing high level expression of a selected protein and stable cell lines useful therein. This method involves culturing a cell line containing amplified copies of a cDNA sequence encoding a steroid or other ligand receptor, and amplified copies of a vector comprising an expression control sequence (incuding a promoter) which is responsive to the complex of said ligand and its receptor in operative association with a selected exogenous protein, in the presence of the ligand. More... »

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