High Level Inducible Expression Of Heterologous Genes


Ontology type: sgo:Patent     


Patent Info

DATE

1989-06-07T00:00

AUTHORS

ISRAEL, DAVID , KAUFMAN, RANDAL, J.

ABSTRACT

A process for producing an expression at a high level of a selected protein and stable cell lines useful in said method comprises culturing a cell line containing enlarged copies of a cDNA sequence encoding a steroid or another ligand receptor and enlarged copies of a vector comprising a regulatory sequence of the expression (including a promoter) which is responsive to complex said ligand and its receptor, which is operatively associated with a selected exogenous protein, in the presence of ligand. More... »

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