Structural biology


Ontology type: npg:Subject  | skos:Concept     


Concept Info

NAME

Structural biology

DESCRIPTION

Structural biology is the study of the molecular structure and dynamics of biological macromolecules, particularly proteins and nucleic acids, and how alterations in their structures affect their function. Structural biology incorporates the principles of molecular biology, biochemistry and biophysics.

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        "id": "http://scigraph.springernature.com/ontologies/subjects/earth-and-environmental-sciences"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/biological-sciences"
      }
    ], 
    "type": [
      "http://www.w3.org/2004/02/skos/core#ConceptScheme"
    ]
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/ontologies/subjects/structural-biology'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/ontologies/subjects/structural-biology'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/ontologies/subjects/structural-biology'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/ontologies/subjects/structural-biology'


 

This table displays all metadata directly associated to this object as RDF triples.

196 TRIPLES      9 PREDICATES      17 URIs      4 LITERALS

Subject Predicate Object
1 sg:ontologies/subjects/structural-biology sgo:license sg:explorer/license/
2 sgo:sdDataset onto_subjects
3 rdf:type npg:Subject
4 skos:Concept
5 rdfs:label Structural biology
6 skos:broader sg:ontologies/subjects/biochemistry
7 sg:ontologies/subjects/biological-sciences
8 skos:definition Structural biology is the study of the molecular structure and dynamics of biological macromolecules, particularly proteins and nucleic acids, and how alterations in their structures affect their function. Structural biology incorporates the principles of molecular biology, biochemistry and biophysics.
9 skos:inScheme sg:ontologies/subjects/
10 skos:narrower sg:ontologies/subjects/atomic-force-microscopy
11 sg:ontologies/subjects/electron-microscopy
12 sg:ontologies/subjects/molecular-modelling
13 sg:ontologies/subjects/nmr-spectroscopy
14 sg:ontologies/subjects/saxs
15 sg:ontologies/subjects/x-ray-crystallography
16 skos:prefLabel Structural biology
17 sg:ontologies/subjects/ dcterms:description The Nature Subjects Taxonomy is a polyhierarchical categorization of scholarly subject areas which are used for the indexing of content by Springer Nature.
18 dcterms:title Nature Subjects Taxonomy
19 sgo:sdDataset onto_subjects
20 rdf:type skos:ConceptScheme
21 skos:hasTopConcept sg:ontologies/subjects/DEPRECATED
22 sg:ontologies/subjects/biological-sciences
23 sg:ontologies/subjects/business-and-commerce
24 sg:ontologies/subjects/earth-and-environmental-sciences
25 sg:ontologies/subjects/health-sciences
26 sg:ontologies/subjects/humanities
27 sg:ontologies/subjects/physical-sciences
28 sg:ontologies/subjects/scientific-community-and-society
29 sg:ontologies/subjects/social-science
30 sg:ontologies/subjects/atomic-force-microscopy sgo:sdDataset onto_subjects
31 rdf:type npg:Subject
32 skos:Concept
33 rdfs:label Atomic force microscopy
34 skos:altLabel AFM
35 Atomic Force Microscope
36 Atomic Force Microscopies
37 Force Microscopies
38 Force Microscopy
39 Scanning Force Microscopies
40 Scanning Force Microscopy
41 skos:broader sg:ontologies/subjects/biophysical-methods
42 sg:ontologies/subjects/microscopy
43 sg:ontologies/subjects/structural-biology
44 sg:ontologies/subjects/structure-determination
45 skos:definition Atomic force microscopy (AFM), a form of scanning probe microscopy, is a technique where a cantilever with a sharp tip is systematically scanned across a sample (biological or material) surface to produce a nanometre-resolution topographic map. AFM can also be used to measure forces between the tip and sample.
46 skos:inScheme sg:ontologies/subjects/
47 skos:prefLabel Atomic force microscopy
48 sg:ontologies/subjects/biochemistry sgo:sdDataset onto_subjects
49 rdf:type npg:Subject
50 skos:Concept
51 rdfs:label Biochemistry
52 skos:altLabel Biological Chemistry
53 skos:broader sg:ontologies/subjects/biological-sciences
54 sg:ontologies/subjects/chemistry
55 skos:definition Biochemistry is the study of the structure and function of biological molecules such as proteins, nucleic acids, carbohydrates and lipids. Biochemistry is also used to describe techniques suited to understanding the interactions and functions of biological molecules, including traditional techniques such as Western blotting, co-immunoprecipitation, and chromatography methods.
56 skos:inScheme sg:ontologies/subjects/
57 skos:narrower sg:ontologies/subjects/biocatalysis
58 sg:ontologies/subjects/biogeochemistry
59 sg:ontologies/subjects/bioinorganic-chemistry
60 sg:ontologies/subjects/biophysical-chemistry
61 sg:ontologies/subjects/carbohydrates
62 sg:ontologies/subjects/chemical-modification
63 sg:ontologies/subjects/cytokines
64 sg:ontologies/subjects/dna
65 sg:ontologies/subjects/enzyme-mechanisms
66 sg:ontologies/subjects/enzymes
67 sg:ontologies/subjects/glycobiology
68 sg:ontologies/subjects/glycomics
69 sg:ontologies/subjects/histocytochemistry
70 sg:ontologies/subjects/hormones
71 sg:ontologies/subjects/immunochemistry
72 sg:ontologies/subjects/ion-channels
73 sg:ontologies/subjects/isoenzymes
74 sg:ontologies/subjects/kinases
75 sg:ontologies/subjects/lipidomics
76 sg:ontologies/subjects/lipids
77 sg:ontologies/subjects/metabolomics
78 sg:ontologies/subjects/metals
79 sg:ontologies/subjects/neurochemistry
80 sg:ontologies/subjects/peptides
81 sg:ontologies/subjects/prions
82 sg:ontologies/subjects/proteases
83 sg:ontologies/subjects/protein-folding
84 sg:ontologies/subjects/proteins
85 sg:ontologies/subjects/proteolysis
86 sg:ontologies/subjects/proteomics
87 sg:ontologies/subjects/rna
88 sg:ontologies/subjects/structural-biology
89 skos:prefLabel Biochemistry
90 sg:ontologies/subjects/biological-sciences sgo:sdDataset onto_subjects
91 rdf:type npg:Subject
92 skos:Concept
93 rdfs:label Biological sciences
94 skos:altLabel Biologic Science
95 Biologic Sciences
96 Biological Science
97 Biological Science Discipline
98 Biological Science Disciplines
99 Life Science
100 Life Sciences
101 skos:definition Biological sciences encompasses all the divisions of natural sciences examining various aspects of vital processes. The concept includes anatomy, physiology, cell biology, biochemistry and biophysics, and covers all organisms from microorganisms, animals to plants.
102 skos:inScheme sg:ontologies/subjects/
103 skos:narrower sg:ontologies/subjects/biochemistry
104 sg:ontologies/subjects/biological-techniques
105 sg:ontologies/subjects/biophysics
106 sg:ontologies/subjects/biotechnology
107 sg:ontologies/subjects/cancer
108 sg:ontologies/subjects/cell-biology
109 sg:ontologies/subjects/chemical-biology
110 sg:ontologies/subjects/computational-biology-and-bioinformatics
111 sg:ontologies/subjects/developmental-biology
112 sg:ontologies/subjects/drug-discovery
113 sg:ontologies/subjects/ecology
114 sg:ontologies/subjects/evolution
115 sg:ontologies/subjects/genetics
116 sg:ontologies/subjects/immunology
117 sg:ontologies/subjects/microbiology
118 sg:ontologies/subjects/molecular-biology
119 sg:ontologies/subjects/neuroscience
120 sg:ontologies/subjects/physiology
121 sg:ontologies/subjects/plant-sciences
122 sg:ontologies/subjects/psychology
123 sg:ontologies/subjects/stem-cells
124 sg:ontologies/subjects/structural-biology
125 sg:ontologies/subjects/systems-biology
126 sg:ontologies/subjects/zoology
127 skos:prefLabel Biological sciences
128 skos:topConceptOf sg:ontologies/subjects/
129 sg:ontologies/subjects/electron-microscopy sgo:sdDataset onto_subjects
130 rdf:type npg:Subject
131 skos:Concept
132 rdfs:label Electron microscopy
133 skos:broader sg:ontologies/subjects/structural-biology
134 sg:ontologies/subjects/structure-determination
135 skos:definition Electron microscopy uses a beam of electrons to illuminate a sample and achieve much higher spatial resolution than light microscopy. Transmission electron microscopy generates an image of the internal structure of a thin sample. Scanning electron microscopy generates a topological image of a sample.
136 skos:inScheme sg:ontologies/subjects/
137 skos:narrower sg:ontologies/subjects/cryoelectron-microscopy
138 sg:ontologies/subjects/cryoelectron-tomography
139 skos:prefLabel Electron microscopy
140 sg:ontologies/subjects/molecular-modelling sgo:sdDataset onto_subjects
141 rdf:type npg:Subject
142 skos:Concept
143 rdfs:label Molecular modelling
144 skos:broader sg:ontologies/subjects/structural-biology
145 sg:ontologies/subjects/structure-determination
146 skos:definition Molecular modelling encompasses all theoretical methods and computational techniques used to mimic and study the structure and behaviour of molecules, ranging from small chemical systems to large biological molecules and material assemblies.
147 skos:inScheme sg:ontologies/subjects/
148 skos:prefLabel Molecular modelling
149 sg:ontologies/subjects/nmr-spectroscopy sgo:sdDataset onto_subjects
150 rdf:type npg:Subject
151 skos:Concept
152 rdfs:label NMR spectroscopy
153 skos:altLabel In Vivo NMR Spectroscopy
154 MR Spectroscopy
155 Magnetic Resonance
156 Magnetic Resonance Spectroscopies
157 Magnetic Resonance Spectroscopy
158 NMR Spectroscopies
159 Nuclear Magnetic Resonance
160 skos:broader sg:ontologies/subjects/analytical-chemistry
161 sg:ontologies/subjects/structural-biology
162 sg:ontologies/subjects/structure-determination
163 sg:ontologies/subjects/techniques-and-instrumentation
164 skos:definition Nuclear magnetic resonance (NMR) spectroscopy is a technique that detects the chemical environment of atomic nuclei by the absorption of radio-frequency electromagnetic radiation when in the presence of a high magnetic field. NMR is used in chemistry and related fields for high-resolution molecular structure determination and the study of molecular dynamics.
165 skos:inScheme sg:ontologies/subjects/
166 skos:narrower sg:ontologies/subjects/solid-state-nmr
167 sg:ontologies/subjects/solution-state-nmr
168 skos:prefLabel NMR spectroscopy
169 sg:ontologies/subjects/saxs sgo:sdDataset onto_subjects
170 rdf:type npg:Subject
171 skos:Concept
172 rdfs:label SAXS
173 skos:altLabel Small-angle X-ray scattering
174 skos:broader sg:ontologies/subjects/structural-biology
175 sg:ontologies/subjects/structure-determination
176 skos:definition Small-angle X-ray scattering (SAXS) is a small-angle scattering (SAS) technique whereby the scattering of X-rays upon interaction with a material or biological molecule in solution is monitored. A SAXS pattern can be used to interpret molecular structure.
177 skos:inScheme sg:ontologies/subjects/
178 skos:prefLabel SAXS
179 sg:ontologies/subjects/x-ray-crystallography sgo:sdDataset onto_subjects
180 rdf:type npg:Subject
181 skos:Concept
182 rdfs:label X-ray crystallography
183 skos:altLabel X Ray Crystallographies
184 X Ray Crystallography
185 Xray Crystallography
186 skos:broader sg:ontologies/subjects/structural-biology
187 sg:ontologies/subjects/structure-determination
188 skos:definition X-ray crystallography is a technique that uses X-ray diffraction patterns to determine high-resolution, three-dimensional structures of molecules such as proteins, small organic molecules, and materials. The substance of interest must be in crystalline form, which typically requires testing various crystallization conditions.
189 skos:inScheme sg:ontologies/subjects/
190 skos:narrower sg:ontologies/subjects/nanocrystallography
191 skos:prefLabel X-ray crystallography
192 skos:Concept sgo:sdDataset for_codes
193 rdf:type rdfs:Class
194 rdfs:Resource
195 rdfs:subClassOf rdfs:Resource
196 skos:Concept
 




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