RNA metabolism


Ontology type: npg:Subject  | skos:Concept     


Concept Info

NAME

RNA metabolism

DESCRIPTION

RNA metabolism refers to any events in the life cycle of ribonucleic acid (RNA) molecules, including their synthesis, folding/unfolding, modification, processing and degradation.

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53 Molecular Genetics
54 skos:broader sg:ontologies/subjects/biological-sciences
55 skos:definition Molecular Biology is the field of biology that studies the composition, structure and interactions of cellular molecules – such as nucleic acids and proteins – that carry out the biological processes essential for the cell’s functions and maintenance.
56 skos:inScheme sg:ontologies/subjects/
57 skos:narrower sg:ontologies/subjects/cell-division
58 sg:ontologies/subjects/chromatin
59 sg:ontologies/subjects/chromosomes
60 sg:ontologies/subjects/crispr-cas-systems
61 sg:ontologies/subjects/dna-damage-and-repair
62 sg:ontologies/subjects/dna-metabolism
63 sg:ontologies/subjects/dna-recombination
64 sg:ontologies/subjects/dna-replication
65 sg:ontologies/subjects/epigenetics
66 sg:ontologies/subjects/non-coding-rnas
67 sg:ontologies/subjects/nuclear-organization
68 sg:ontologies/subjects/post-translational-modifications
69 sg:ontologies/subjects/protein-folding
70 sg:ontologies/subjects/proteolysis
71 sg:ontologies/subjects/proteomics
72 sg:ontologies/subjects/riboswitches
73 sg:ontologies/subjects/ribozymes
74 sg:ontologies/subjects/rna-metabolism
75 sg:ontologies/subjects/rnai
76 sg:ontologies/subjects/single-molecule-biophysics
77 sg:ontologies/subjects/transcription
78 sg:ontologies/subjects/transcriptomics
79 sg:ontologies/subjects/translation
80 sg:ontologies/subjects/transposition
81 skos:prefLabel Molecular biology
82 sg:ontologies/subjects/rna-decay sgo:sdDataset onto_subjects
83 rdf:type npg:Subject
84 skos:Concept
85 rdfs:label RNA decay
86 skos:altLabel RNA Degradation
87 RNA Instability
88 RNA Stability
89 mRNA Decay
90 mRNA Degradation
91 mRNA Instability
92 mRNA Stability
93 mRNA Transcript Degradation
94 skos:broader sg:ontologies/subjects/rna-metabolism
95 skos:definition RNA decay is the process by which ribonucleic acid (RNA) molecules are enzymatically degraded. RNA decay is a regulated event and serves to control levels of particular RNA molecules. A specific example is nonsense-mediated mRNA decay (NMD), a process that eliminates transcripts containing premature stop codons.
96 skos:inScheme sg:ontologies/subjects/
97 skos:prefLabel RNA decay
98 sg:ontologies/subjects/rna-editing sgo:sdDataset onto_subjects
99 rdf:type npg:Subject
100 skos:Concept
101 rdfs:label RNA editing
102 skos:altLabel RNA Editings
103 skos:broader sg:ontologies/subjects/rna-metabolism
104 skos:definition RNA editing is the process by which ribonucleic acid (RNA) molecules are enzymatically modified post synthesis on specific nucleosides. Examples of RNA editing include pseudouridylation (the isomerization of uridine residues) and deamination (removal of an amine group from cytidine to give rise to uridine, or C-to-U editing).
105 skos:inScheme sg:ontologies/subjects/
106 skos:prefLabel RNA editing
107 sg:ontologies/subjects/rna-folding sgo:sdDataset onto_subjects
108 rdf:type npg:Subject
109 skos:Concept
110 rdfs:label RNA folding
111 skos:broader sg:ontologies/subjects/rna-metabolism
112 skos:definition RNA folding is the process by which a linear ribonucleic acid (RNA) molecule acquires secondary structure through intra-molecular interactions. The folded domains of RNA molecules are often the sites of specific interactions with proteins in forming RNA–protein (ribonucleoprotein) complexes.
113 skos:inScheme sg:ontologies/subjects/
114 skos:prefLabel RNA folding
115 sg:ontologies/subjects/rna-modification sgo:sdDataset onto_subjects
116 rdf:type npg:Subject
117 skos:Concept
118 rdfs:label RNA modification
119 skos:broader sg:ontologies/subjects/rna-metabolism
120 skos:definition RNA modifications are changes to the chemical composition of ribonucleic acid (RNA) molecules post-synthesis that have the potential to alter function or stability. An example of RNA modification is the addition of a methylated guanine nucleotide “cap” to the 5’-end of messenger RNAs (mRNAs).
121 skos:inScheme sg:ontologies/subjects/
122 skos:prefLabel RNA modification
123 sg:ontologies/subjects/rna-quality-control sgo:sdDataset onto_subjects
124 rdf:type npg:Subject
125 skos:Concept
126 rdfs:label RNA quality control
127 skos:broader sg:ontologies/subjects/rna-metabolism
128 skos:definition RNA quality control is the active process by which ribonucleic acid (RNA) molecules are monitored for integrity. The RNA quality control machinery directs the degradation of compromised RNA molecules.
129 skos:inScheme sg:ontologies/subjects/
130 skos:prefLabel RNA quality control
131 sg:ontologies/subjects/rna-splicing sgo:sdDataset onto_subjects
132 rdf:type npg:Subject
133 skos:Concept
134 rdfs:label RNA splicing
135 skos:altLabel RNA Splicings
136 skos:broader sg:ontologies/subjects/genetics
137 sg:ontologies/subjects/rna-metabolism
138 skos:definition RNA splicing is a modification of the nascent pre-messenger RNA (pre-mRNA) transcript in which introns are removed and exons are joined prior to translation. For many eukaryotic introns, splicing is done in a series of reactions which are catalyzed by the spliceosome, a complex of small nuclear ribonucleoproteins (snRNPs) and associated proteins, but there are also self-splicing introns.
139 skos:inScheme sg:ontologies/subjects/
140 skos:prefLabel RNA splicing
141 sg:ontologies/subjects/rna-transport sgo:sdDataset onto_subjects
142 rdf:type npg:Subject
143 skos:Concept
144 rdfs:label RNA transport
145 skos:altLabel Messenger RNA Sorting
146 RNA Sorting
147 Ribonucleic Acid Transport
148 mRNA Sorting
149 skos:broader sg:ontologies/subjects/nuclear-transport
150 sg:ontologies/subjects/rna-metabolism
151 skos:definition RNA transport is the process by which ribonucleic acid (RNA) molecules are actively transported from one location within the cell to another. Examples include the export of RNAs from the nucleus to the cytoplasm through the nuclear pores, and the microtubule-assisted movement of specific RNAs along nerve fibres (axons).
152 skos:inScheme sg:ontologies/subjects/
153 skos:prefLabel RNA transport
154 skos:Concept sgo:sdDataset for_codes
155 rdf:type rdfs:Class
156 rdfs:Resource
157 rdfs:subClassOf rdfs:Resource
158 skos:Concept
 




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