Preclinical research


Ontology type: npg:Subject  | skos:Concept     


Concept Info

NAME

Preclinical research

DESCRIPTION

Preclinical research involves the evaluation of potential therapeutic interventions in cells and animals. Candidates for entry into clinical trials can then be selected based on their effectiveness and safety in disease models. All drugs require data from various toxicological preclinical studies to support their potential safety in humans before clinical trials can begin.

Broader Concepts

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/pre-clinical-studies", 
    "rdfs:label": "Preclinical research", 
    "sdDataset": "onto_subjects", 
    "skos:altLabel": [
      {
        "@language": "en", 
        "@value": "Pre-clinical studies"
      }
    ], 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/medical-research"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Preclinical research involves the evaluation of potential therapeutic interventions in cells and animals. Candidates for entry into clinical trials can then be selected based on their effectiveness and safety in disease models. All drugs require data from various toxicological preclinical studies to support their potential safety in humans before clinical trials can begin. "
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Preclinical research"
      }
    ], 
    "type": [
      "http://ns.nature.com/terms/Subject", 
      "http://www.w3.org/2004/02/skos/core#Concept"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/medical-research", 
    "rdfs:label": "Medical research", 
    "sdDataset": "onto_subjects", 
    "skos:altLabel": [
      {
        "@language": "en", 
        "@value": "Clinical Research"
      }
    ], 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/health-sciences"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Medical research involves research in a wide range of fields, such as biology, chemistry, pharmacology and toxicology with the goal of developing new medicines or medical procedures or improving the application of those already available. It can be viewed as encompassing preclinical research (for example, in cellular systems and animal models) and clinical research (for example, clinical trials).  "
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:narrower": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/experimental-models-of-disease"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/drug-development"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/epidemiology"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/outcomes-research"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/paediatric-research"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/translational-research"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/biomarkers"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/genetics-research"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/study-design"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/pre-clinical-studies"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/stem-cell-research"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Medical research"
      }
    ], 
    "type": [
      "http://www.w3.org/2004/02/skos/core#Concept", 
      "http://ns.nature.com/terms/Subject"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://www.w3.org/2004/02/skos/core#Concept", 
    "rdfs:subClassOf": [
      {
        "id": "http://www.w3.org/2004/02/skos/core#Concept"
      }, 
      {
        "id": "http://www.w3.org/2000/01/rdf-schema#Resource"
      }
    ], 
    "sdDataset": "for_codes", 
    "type": [
      "http://www.w3.org/2000/01/rdf-schema#Resource", 
      "http://www.w3.org/2000/01/rdf-schema#Class"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "dcterms:description": [
      {
        "@language": "en", 
        "@value": "The Nature Subjects Taxonomy is a polyhierarchical categorization of scholarly subject areas which are used for the indexing of content by Springer Nature."
      }
    ], 
    "dcterms:title": [
      {
        "@language": "en", 
        "@value": "Nature Subjects Taxonomy"
      }
    ], 
    "id": "http://scigraph.springernature.com/ontologies/subjects/", 
    "sdDataset": "onto_subjects", 
    "skos:hasTopConcept": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/physical-sciences"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/DEPRECATED"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/business-and-commerce"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/humanities"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/social-science"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/health-sciences"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/scientific-community-and-society"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/earth-and-environmental-sciences"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/biological-sciences"
      }
    ], 
    "type": [
      "http://www.w3.org/2004/02/skos/core#ConceptScheme"
    ]
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/ontologies/subjects/pre-clinical-studies'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/ontologies/subjects/pre-clinical-studies'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/ontologies/subjects/pre-clinical-studies'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/ontologies/subjects/pre-clinical-studies'


 

This table displays all metadata directly associated to this object as RDF triples.

48 TRIPLES      9 PREDICATES      11 URIs      5 LITERALS

Subject Predicate Object
1 sg:ontologies/subjects/pre-clinical-studies sgo:license sg:explorer/license/
2 sgo:sdDataset onto_subjects
3 rdf:type npg:Subject
4 skos:Concept
5 rdfs:label Preclinical research
6 skos:altLabel Pre-clinical studies
7 skos:broader sg:ontologies/subjects/medical-research
8 skos:definition Preclinical research involves the evaluation of potential therapeutic interventions in cells and animals. Candidates for entry into clinical trials can then be selected based on their effectiveness and safety in disease models. All drugs require data from various toxicological preclinical studies to support their potential safety in humans before clinical trials can begin.
9 skos:inScheme sg:ontologies/subjects/
10 skos:prefLabel Preclinical research
11 sg:ontologies/subjects/ dcterms:description The Nature Subjects Taxonomy is a polyhierarchical categorization of scholarly subject areas which are used for the indexing of content by Springer Nature.
12 dcterms:title Nature Subjects Taxonomy
13 sgo:sdDataset onto_subjects
14 rdf:type skos:ConceptScheme
15 skos:hasTopConcept sg:ontologies/subjects/DEPRECATED
16 sg:ontologies/subjects/biological-sciences
17 sg:ontologies/subjects/business-and-commerce
18 sg:ontologies/subjects/earth-and-environmental-sciences
19 sg:ontologies/subjects/health-sciences
20 sg:ontologies/subjects/humanities
21 sg:ontologies/subjects/physical-sciences
22 sg:ontologies/subjects/scientific-community-and-society
23 sg:ontologies/subjects/social-science
24 sg:ontologies/subjects/medical-research sgo:sdDataset onto_subjects
25 rdf:type npg:Subject
26 skos:Concept
27 rdfs:label Medical research
28 skos:altLabel Clinical Research
29 skos:broader sg:ontologies/subjects/health-sciences
30 skos:definition Medical research involves research in a wide range of fields, such as biology, chemistry, pharmacology and toxicology with the goal of developing new medicines or medical procedures or improving the application of those already available. It can be viewed as encompassing preclinical research (for example, in cellular systems and animal models) and clinical research (for example, clinical trials).
31 skos:inScheme sg:ontologies/subjects/
32 skos:narrower sg:ontologies/subjects/biomarkers
33 sg:ontologies/subjects/drug-development
34 sg:ontologies/subjects/epidemiology
35 sg:ontologies/subjects/experimental-models-of-disease
36 sg:ontologies/subjects/genetics-research
37 sg:ontologies/subjects/outcomes-research
38 sg:ontologies/subjects/paediatric-research
39 sg:ontologies/subjects/pre-clinical-studies
40 sg:ontologies/subjects/stem-cell-research
41 sg:ontologies/subjects/study-design
42 sg:ontologies/subjects/translational-research
43 skos:prefLabel Medical research
44 skos:Concept sgo:sdDataset for_codes
45 rdf:type rdfs:Class
46 rdfs:Resource
47 rdfs:subClassOf rdfs:Resource
48 skos:Concept
 




Preview window. Press ESC to close (or click here)


...