Penicillin-binding proteins


Ontology type: npg:Subject  | skos:Concept     


Concept Info

NAME

Penicillin-binding proteins

DESCRIPTION

Penicillin-binding proteins (PBPs) are bacterial proteins that bind to penicillin and other antibiotics of the β-lactam class. Penicillin-binding proteins are generally enzymes involved in peptidoglycan biosynthesis, so contribute essential roles in bacterial cell wall biosynthesis. PBPs bind β-lactam antibiotics because their chemical structure is similar to that of the sugar–amino acid backbone that forms peptidoglycan.

Broader Concepts

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This table displays all metadata directly associated to this object as RDF triples.

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Subject Predicate Object
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6 skos:altLabel Penicillin Binding Protein
7 Penicillin Binding Protein 1
8 Penicillin Binding Protein 1A
9 Penicillin Binding Protein 1b
10 Penicillin Binding Protein 2
11 Penicillin Binding Protein 2a
12 Penicillin Binding Protein 2b
13 Penicillin Binding Protein 3
14 Penicillin Binding Protein 4
15 Penicillin Binding Protein 5
16 Penicillin Binding Protein 6
17 Penicillin Binding Protein 7
18 Penicillin Binding Proteins
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22 Penicillin-Binding Protein 1b
23 Penicillin-Binding Protein 2
24 Penicillin-Binding Protein 2a
25 Penicillin-Binding Protein 2b
26 Penicillin-Binding Protein 3
27 Penicillin-Binding Protein 4
28 Penicillin-Binding Protein 5
29 Penicillin-Binding Protein 6
30 Penicillin-Binding Protein 7
31 Penicillin-Binding Protein-2a
32 Peptidoglycan Synthetase
33 skos:broader sg:ontologies/subjects/enzymes
34 skos:definition Penicillin-binding proteins (PBPs) are bacterial proteins that bind to penicillin and other antibiotics of the β-lactam class. Penicillin-binding proteins are generally enzymes involved in peptidoglycan biosynthesis, so contribute essential roles in bacterial cell wall biosynthesis. PBPs bind β-lactam antibiotics because their chemical structure is similar to that of the sugar–amino acid backbone that forms peptidoglycan.
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