Nuclear organization


Ontology type: npg:Subject  | skos:Concept     


Concept Info

NAME

Nuclear organization

DESCRIPTION

Nuclear organization refers to the spatial distribution of nuclear contents and components in a way that reflects or facilitates their activities. For example, chromatin or nucleoli may become more condensed or expanded in response to changes in gene expression or cellular growth rate.

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This table displays all metadata directly associated to this object as RDF triples.

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3 rdf:type npg:Subject
4 skos:Concept
5 rdfs:label Nuclear organization
6 skos:broader sg:ontologies/subjects/cell-biology
7 sg:ontologies/subjects/molecular-biology
8 skos:definition Nuclear organization refers to the spatial distribution of nuclear contents and components in a way that reflects or facilitates their activities. For example, chromatin or nucleoli may become more condensed or expanded in response to changes in gene expression or cellular growth rate.
9 skos:inScheme sg:ontologies/subjects/
10 skos:narrower sg:ontologies/subjects/cajal-bodies
11 sg:ontologies/subjects/nuclear-envelope
12 sg:ontologies/subjects/nucleolus
13 sg:ontologies/subjects/nucleoskeleton
14 sg:ontologies/subjects/pml-bodies
15 sg:ontologies/subjects/speckles
16 sg:ontologies/subjects/stress-granules
17 skos:prefLabel Nuclear organization
18 sg:ontologies/subjects/ dcterms:description The Nature Subjects Taxonomy is a polyhierarchical categorization of scholarly subject areas which are used for the indexing of content by Springer Nature.
19 dcterms:title Nature Subjects Taxonomy
20 sgo:sdDataset onto_subjects
21 rdf:type skos:ConceptScheme
22 skos:hasTopConcept sg:ontologies/subjects/DEPRECATED
23 sg:ontologies/subjects/biological-sciences
24 sg:ontologies/subjects/business-and-commerce
25 sg:ontologies/subjects/earth-and-environmental-sciences
26 sg:ontologies/subjects/health-sciences
27 sg:ontologies/subjects/humanities
28 sg:ontologies/subjects/physical-sciences
29 sg:ontologies/subjects/scientific-community-and-society
30 sg:ontologies/subjects/social-science
31 sg:ontologies/subjects/cajal-bodies sgo:sdDataset onto_subjects
32 rdf:type npg:Subject
33 skos:Concept
34 rdfs:label Cajal bodies
35 skos:altLabel Accessory Bodies of Cajal
36 Cajal Accessory Bodies
37 Coiled Bodies
38 Coiled Body
39 skos:broader sg:ontologies/subjects/nuclear-organization
40 skos:definition Cajal bodies are regions within the nucleus that are enriched in proteins and RNAs involved in mRNA processing. They are the main sites for the assembly of small nuclear ribonucleoproteins (snRNPs).
41 skos:inScheme sg:ontologies/subjects/
42 skos:prefLabel Cajal bodies
43 sg:ontologies/subjects/cell-biology sgo:sdDataset onto_subjects
44 rdf:type npg:Subject
45 skos:Concept
46 rdfs:label Cell biology
47 skos:altLabel Cell Biologies
48 Cellular Biologies
49 Cellular Biology
50 Cytology
51 skos:broader sg:ontologies/subjects/biological-sciences
52 skos:definition Cell biology is the discipline of biological sciences that studies the structure, physiology, growth, reproduction and death of cells. Research in cell biology uses microscopic and molecular tools and examines all cell types, from unicellular organisms such as protozoa to the specialised cells that consitutute multicellular organisms.
53 skos:inScheme sg:ontologies/subjects/
54 skos:narrower sg:ontologies/subjects/autophagy
55 sg:ontologies/subjects/cell-adhesion
56 sg:ontologies/subjects/cell-death
57 sg:ontologies/subjects/cell-division
58 sg:ontologies/subjects/cell-growth
59 sg:ontologies/subjects/cell-migration
60 sg:ontologies/subjects/cell-polarity
61 sg:ontologies/subjects/cell-signalling
62 sg:ontologies/subjects/cellular-imaging
63 sg:ontologies/subjects/chromosomes
64 sg:ontologies/subjects/circadian-rhythms
65 sg:ontologies/subjects/cytoskeleton
66 sg:ontologies/subjects/glycobiology
67 sg:ontologies/subjects/mechanisms-of-disease
68 sg:ontologies/subjects/membrane-trafficking
69 sg:ontologies/subjects/nuclear-organization
70 sg:ontologies/subjects/nuclear-transport
71 sg:ontologies/subjects/organelles
72 sg:ontologies/subjects/post-translational-modifications
73 sg:ontologies/subjects/protein-folding
74 sg:ontologies/subjects/protein-transport
75 sg:ontologies/subjects/proteolysis
76 sg:ontologies/subjects/senescence
77 skos:prefLabel Cell biology
78 sg:ontologies/subjects/molecular-biology sgo:sdDataset onto_subjects
79 rdf:type npg:Subject
80 skos:Concept
81 rdfs:label Molecular biology
82 skos:altLabel Biochemical Genetic
83 Biochemical Genetics
84 Molecular Genetic
85 Molecular Genetics
86 skos:broader sg:ontologies/subjects/biological-sciences
87 skos:definition Molecular Biology is the field of biology that studies the composition, structure and interactions of cellular molecules – such as nucleic acids and proteins – that carry out the biological processes essential for the cell’s functions and maintenance.
88 skos:inScheme sg:ontologies/subjects/
89 skos:narrower sg:ontologies/subjects/cell-division
90 sg:ontologies/subjects/chromatin
91 sg:ontologies/subjects/chromosomes
92 sg:ontologies/subjects/crispr-cas-systems
93 sg:ontologies/subjects/dna-damage-and-repair
94 sg:ontologies/subjects/dna-metabolism
95 sg:ontologies/subjects/dna-recombination
96 sg:ontologies/subjects/dna-replication
97 sg:ontologies/subjects/epigenetics
98 sg:ontologies/subjects/non-coding-rnas
99 sg:ontologies/subjects/nuclear-organization
100 sg:ontologies/subjects/post-translational-modifications
101 sg:ontologies/subjects/protein-folding
102 sg:ontologies/subjects/proteolysis
103 sg:ontologies/subjects/proteomics
104 sg:ontologies/subjects/riboswitches
105 sg:ontologies/subjects/ribozymes
106 sg:ontologies/subjects/rna-metabolism
107 sg:ontologies/subjects/rnai
108 sg:ontologies/subjects/single-molecule-biophysics
109 sg:ontologies/subjects/transcription
110 sg:ontologies/subjects/transcriptomics
111 sg:ontologies/subjects/translation
112 sg:ontologies/subjects/transposition
113 skos:prefLabel Molecular biology
114 sg:ontologies/subjects/nuclear-envelope sgo:sdDataset onto_subjects
115 rdf:type npg:Subject
116 skos:Concept
117 rdfs:label Nuclear envelope
118 skos:altLabel Nuclear Envelopes
119 Nuclear Membrane
120 Nuclear Membranes
121 skos:broader sg:ontologies/subjects/nuclear-organization
122 skos:definition The nuclear envelope is a structure that surrounds and defines the nucleus and separates it from the cytoplasm. It is comprised of inner and outer membranes separated by the perinuclear space, and contains specialized nuclear pore structures that permit communication and transport between the nucleus and cytoplasm.
123 skos:inScheme sg:ontologies/subjects/
124 skos:prefLabel Nuclear envelope
125 sg:ontologies/subjects/nucleolus sgo:sdDataset onto_subjects
126 rdf:type npg:Subject
127 skos:Concept
128 rdfs:label Nucleolus
129 skos:altLabel Cell Nucleoli
130 Cell Nucleolus
131 Plasmosome
132 Plasmosomes
133 skos:broader sg:ontologies/subjects/nuclear-organization
134 skos:definition The nucleolus is a region within the nucleus that primarily functions as the site for the transcription of ribosomal RNA (rRNA) genes, the processing of precursor rRNAs into mature components of ribosomes, and the initial steps of ribosome assembly.
135 skos:inScheme sg:ontologies/subjects/
136 skos:prefLabel Nucleolus
137 sg:ontologies/subjects/nucleoskeleton sgo:sdDataset onto_subjects
138 rdf:type npg:Subject
139 skos:Concept
140 rdfs:label Nucleoskeleton
141 skos:altLabel Nuclear Matrices
142 Nuclear Scaffold
143 Nuclear Scaffolds
144 skos:broader sg:ontologies/subjects/nuclear-organization
145 skos:definition The nucleoskeleton, also referred to as nuclear matrix, is the filamentous component of the nucleus not solubilized during extraction with high salt buffers. The nucleoskeleton is akin to a scaffold with which other components of the nucleus (proteins, RNA, DNA) can interact to fix their positions within the nucleus.
146 skos:inScheme sg:ontologies/subjects/
147 skos:prefLabel Nucleoskeleton
148 sg:ontologies/subjects/pml-bodies sgo:sdDataset onto_subjects
149 rdf:type npg:Subject
150 skos:Concept
151 rdfs:label PML bodies
152 skos:altLabel Nuclear bodies
153 Nuclear dots
154 nuclear domains
155 skos:broader sg:ontologies/subjects/nuclear-organization
156 skos:definition PML (promyelocytic leukaemia) bodies are spherical structures in the nucleus that can measure up to 1 µM in diameter. The principal organizing component of PML bodies is the PML protein. PML bodies vary in composition and have been implicated in cellular processes such as telomere lengthening and the DNA damage response.
157 skos:inScheme sg:ontologies/subjects/
158 skos:prefLabel PML bodies
159 sg:ontologies/subjects/speckles sgo:sdDataset onto_subjects
160 rdf:type npg:Subject
161 skos:Concept
162 rdfs:label Nuclear speckles
163 skos:broader sg:ontologies/subjects/nuclear-organization
164 skos:definition Nuclear speckles are structures that can be observed by immunofluorescence microscopy as a punctate pattern within the nucleus of mammalian cells. Nuclear speckles are dynamic and their composition can change over time, but they are generally enriched in pre-mRNA splicing factors and co-localize with actively transcribed chromatin regions.
165 skos:inScheme sg:ontologies/subjects/
166 skos:prefLabel Nuclear speckles
167 sg:ontologies/subjects/stress-granules sgo:sdDataset onto_subjects
168 rdf:type npg:Subject
169 skos:Concept
170 rdfs:label Stress granules
171 skos:broader sg:ontologies/subjects/nuclear-organization
172 skos:definition Stress granules are aggregates composed of proteins and RNA molecules – mostly stalled translation initiation complexes – that usually form in a reversible manner upon cellular stress. Stress granules can also precipitate the formation of toxic protein aggregates such as those seen during the progression of certain types of neurological disease.
173 skos:inScheme sg:ontologies/subjects/
174 skos:prefLabel Stress granules
175 skos:Concept sgo:sdDataset for_codes
176 rdf:type rdfs:Class
177 rdfs:Resource
178 rdfs:subClassOf rdfs:Resource
179 skos:Concept
 




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