Microsatellite instability


Ontology type: npg:Subject  | skos:Concept     


Concept Info

NAME

Microsatellite instability

DESCRIPTION

Microsatellite instability is genetic instability in short nucleotide repeats (microsatellites) due to a high mutation rate as a result of abnormal DNA mismatch repair. Rather than correcting errors that occur spontaneously during DNA replication, cells with impaired mismatch repair accumulate these errors. These sequences are not preserved faithfully through DNA replication and novel microsatellites are created.

Broader Concepts

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/microsatellite-instability", 
    "rdfs:label": "Microsatellite instability", 
    "sdDataset": "onto_subjects", 
    "skos:altLabel": [
      {
        "@language": "en", 
        "@value": "Replication Error Phenotypes"
      }, 
      {
        "@language": "en", 
        "@value": "Replication Error Phenotype"
      }
    ], 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/genomic-instability"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Microsatellite instability is genetic instability in short nucleotide repeats (microsatellites) due to a high mutation rate as a result of abnormal DNA mismatch repair. Rather than correcting errors that occur spontaneously during DNA replication, cells with impaired mismatch repair accumulate these errors. These sequences are not preserved faithfully through DNA replication and novel microsatellites are created."
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Microsatellite instability"
      }
    ], 
    "type": [
      "http://ns.nature.com/terms/Subject", 
      "http://www.w3.org/2004/02/skos/core#Concept"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://scigraph.springernature.com/ontologies/subjects/genomic-instability", 
    "rdfs:label": "Genomic instability", 
    "sdDataset": "onto_subjects", 
    "skos:altLabel": [
      {
        "@language": "en", 
        "@value": "Genomic Stabilities"
      }, 
      {
        "@language": "en", 
        "@value": "Genomic Stability"
      }, 
      {
        "@language": "en", 
        "@value": "Genome Instability"
      }, 
      {
        "@language": "en", 
        "@value": "Genomic Instabilities"
      }, 
      {
        "@language": "en", 
        "@value": "Genome Stabilities"
      }, 
      {
        "@language": "en", 
        "@value": "Genome Instabilities"
      }, 
      {
        "@language": "en", 
        "@value": "Genome Stability"
      }
    ], 
    "skos:broader": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/mutation"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/genetics"
      }
    ], 
    "skos:definition": [
      {
        "@language": "en", 
        "@value": "Chromosome instability describes the increased probability of acquiring chromosomal aberrations due to defects in processes such as DNA repair, replication or chromosome segregation. "
      }
    ], 
    "skos:inScheme": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/"
      }
    ], 
    "skos:narrower": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/microsatellite-instability"
      }
    ], 
    "skos:prefLabel": [
      {
        "@language": "en", 
        "@value": "Genomic instability"
      }
    ], 
    "type": [
      "http://www.w3.org/2004/02/skos/core#Concept", 
      "http://ns.nature.com/terms/Subject"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "id": "http://www.w3.org/2004/02/skos/core#Concept", 
    "rdfs:subClassOf": [
      {
        "id": "http://www.w3.org/2004/02/skos/core#Concept"
      }, 
      {
        "id": "http://www.w3.org/2000/01/rdf-schema#Resource"
      }
    ], 
    "sdDataset": "for_codes", 
    "type": [
      "http://www.w3.org/2000/01/rdf-schema#Resource", 
      "http://www.w3.org/2000/01/rdf-schema#Class"
    ]
  }, 
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "dcterms:description": [
      {
        "@language": "en", 
        "@value": "The Nature Subjects Taxonomy is a polyhierarchical categorization of scholarly subject areas which are used for the indexing of content by Springer Nature."
      }
    ], 
    "dcterms:title": [
      {
        "@language": "en", 
        "@value": "Nature Subjects Taxonomy"
      }
    ], 
    "id": "http://scigraph.springernature.com/ontologies/subjects/", 
    "sdDataset": "onto_subjects", 
    "skos:hasTopConcept": [
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/physical-sciences"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/DEPRECATED"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/business-and-commerce"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/humanities"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/social-science"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/health-sciences"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/scientific-community-and-society"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/earth-and-environmental-sciences"
      }, 
      {
        "id": "http://scigraph.springernature.com/ontologies/subjects/biological-sciences"
      }
    ], 
    "type": [
      "http://www.w3.org/2004/02/skos/core#ConceptScheme"
    ]
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/ontologies/subjects/microsatellite-instability'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/ontologies/subjects/microsatellite-instability'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/ontologies/subjects/microsatellite-instability'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/ontologies/subjects/microsatellite-instability'


 

This table displays all metadata directly associated to this object as RDF triples.

46 TRIPLES      9 PREDICATES      12 URIs      6 LITERALS

Subject Predicate Object
1 sg:ontologies/subjects/microsatellite-instability sgo:license sg:explorer/license/
2 sgo:sdDataset onto_subjects
3 rdf:type npg:Subject
4 skos:Concept
5 rdfs:label Microsatellite instability
6 skos:altLabel Replication Error Phenotype
7 Replication Error Phenotypes
8 skos:broader sg:ontologies/subjects/genomic-instability
9 skos:definition Microsatellite instability is genetic instability in short nucleotide repeats (microsatellites) due to a high mutation rate as a result of abnormal DNA mismatch repair. Rather than correcting errors that occur spontaneously during DNA replication, cells with impaired mismatch repair accumulate these errors. These sequences are not preserved faithfully through DNA replication and novel microsatellites are created.
10 skos:inScheme sg:ontologies/subjects/
11 skos:prefLabel Microsatellite instability
12 sg:ontologies/subjects/ dcterms:description The Nature Subjects Taxonomy is a polyhierarchical categorization of scholarly subject areas which are used for the indexing of content by Springer Nature.
13 dcterms:title Nature Subjects Taxonomy
14 sgo:sdDataset onto_subjects
15 rdf:type skos:ConceptScheme
16 skos:hasTopConcept sg:ontologies/subjects/DEPRECATED
17 sg:ontologies/subjects/biological-sciences
18 sg:ontologies/subjects/business-and-commerce
19 sg:ontologies/subjects/earth-and-environmental-sciences
20 sg:ontologies/subjects/health-sciences
21 sg:ontologies/subjects/humanities
22 sg:ontologies/subjects/physical-sciences
23 sg:ontologies/subjects/scientific-community-and-society
24 sg:ontologies/subjects/social-science
25 sg:ontologies/subjects/genomic-instability sgo:sdDataset onto_subjects
26 rdf:type npg:Subject
27 skos:Concept
28 rdfs:label Genomic instability
29 skos:altLabel Genome Instabilities
30 Genome Instability
31 Genome Stabilities
32 Genome Stability
33 Genomic Instabilities
34 Genomic Stabilities
35 Genomic Stability
36 skos:broader sg:ontologies/subjects/genetics
37 sg:ontologies/subjects/mutation
38 skos:definition Chromosome instability describes the increased probability of acquiring chromosomal aberrations due to defects in processes such as DNA repair, replication or chromosome segregation.
39 skos:inScheme sg:ontologies/subjects/
40 skos:narrower sg:ontologies/subjects/microsatellite-instability
41 skos:prefLabel Genomic instability
42 skos:Concept sgo:sdDataset for_codes
43 rdf:type rdfs:Class
44 rdfs:Resource
45 rdfs:subClassOf rdfs:Resource
46 skos:Concept
 




Preview window. Press ESC to close (or click here)


...