Metals


Ontology type: npg:Subject  | skos:Concept     


Concept Info

NAME

Metals

DESCRIPTION

Metals are electropositive chemical elements, and as such have a propensity to form cations, which they are found as – often bound in metalloproteins – in living systems. Many metals play important roles in living systems; for instance sodium and potassium, which are important for maintaining osmotic equilibrium, as well as calcium, magnesium, iron and copper.

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15 skos:prefLabel Metals
16 sg:ontologies/subjects/ dcterms:description The Nature Subjects Taxonomy is a polyhierarchical categorization of scholarly subject areas which are used for the indexing of content by Springer Nature.
17 dcterms:title Nature Subjects Taxonomy
18 sgo:sdDataset onto_subjects
19 rdf:type skos:ConceptScheme
20 skos:hasTopConcept sg:ontologies/subjects/DEPRECATED
21 sg:ontologies/subjects/biological-sciences
22 sg:ontologies/subjects/business-and-commerce
23 sg:ontologies/subjects/earth-and-environmental-sciences
24 sg:ontologies/subjects/health-sciences
25 sg:ontologies/subjects/humanities
26 sg:ontologies/subjects/physical-sciences
27 sg:ontologies/subjects/scientific-community-and-society
28 sg:ontologies/subjects/social-science
29 sg:ontologies/subjects/biochemistry sgo:sdDataset onto_subjects
30 rdf:type npg:Subject
31 skos:Concept
32 rdfs:label Biochemistry
33 skos:altLabel Biological Chemistry
34 skos:broader sg:ontologies/subjects/biological-sciences
35 sg:ontologies/subjects/chemistry
36 skos:definition Biochemistry is the study of the structure and function of biological molecules such as proteins, nucleic acids, carbohydrates and lipids. Biochemistry is also used to describe techniques suited to understanding the interactions and functions of biological molecules, including traditional techniques such as Western blotting, co-immunoprecipitation, and chromatography methods.
37 skos:inScheme sg:ontologies/subjects/
38 skos:narrower sg:ontologies/subjects/biocatalysis
39 sg:ontologies/subjects/biogeochemistry
40 sg:ontologies/subjects/bioinorganic-chemistry
41 sg:ontologies/subjects/biophysical-chemistry
42 sg:ontologies/subjects/carbohydrates
43 sg:ontologies/subjects/chemical-modification
44 sg:ontologies/subjects/cytokines
45 sg:ontologies/subjects/dna
46 sg:ontologies/subjects/enzyme-mechanisms
47 sg:ontologies/subjects/enzymes
48 sg:ontologies/subjects/glycobiology
49 sg:ontologies/subjects/glycomics
50 sg:ontologies/subjects/histocytochemistry
51 sg:ontologies/subjects/hormones
52 sg:ontologies/subjects/immunochemistry
53 sg:ontologies/subjects/ion-channels
54 sg:ontologies/subjects/isoenzymes
55 sg:ontologies/subjects/kinases
56 sg:ontologies/subjects/lipidomics
57 sg:ontologies/subjects/lipids
58 sg:ontologies/subjects/metabolomics
59 sg:ontologies/subjects/metals
60 sg:ontologies/subjects/neurochemistry
61 sg:ontologies/subjects/peptides
62 sg:ontologies/subjects/prions
63 sg:ontologies/subjects/proteases
64 sg:ontologies/subjects/protein-folding
65 sg:ontologies/subjects/proteins
66 sg:ontologies/subjects/proteolysis
67 sg:ontologies/subjects/proteomics
68 sg:ontologies/subjects/rna
69 sg:ontologies/subjects/structural-biology
70 skos:prefLabel Biochemistry
71 sg:ontologies/subjects/calcium sgo:sdDataset onto_subjects
72 rdf:type npg:Subject
73 skos:Concept
74 rdfs:label Calcium
75 skos:altLabel Blood Coagulation Factor IV
76 Ca
77 Ca2+
78 Coagulation Factor IV
79 Factor IV
80 skos:broader sg:ontologies/subjects/metals
81 skos:definition Calcium (Ca, atomic number 20) is an abundant alkaline earth metal which exists in living systems as Ca2+ ions. Mobilization of calcium stores within cells is important for physiological processes, including oocyte activation during fertilization. Calcium is also involved in multiple cellular signalling pathways, including synaptic transmission in nerve cells and cell motility.
82 skos:inScheme sg:ontologies/subjects/
83 skos:prefLabel Calcium
84 sg:ontologies/subjects/chemical-biology sgo:sdDataset onto_subjects
85 rdf:type npg:Subject
86 skos:Concept
87 rdfs:label Chemical biology
88 skos:broader sg:ontologies/subjects/biological-sciences
89 sg:ontologies/subjects/chemistry
90 skos:definition Chemical biology is the study of the chemicals and chemical reactions involved in biological processes, incorporating the disciplines of bioorganic chemistry, biochemistry, cell biology and pharmacology. Chemicals – including natural small molecules, such as lipids, carbohydrates and metals, or non-natural probe or drug molecules – are used to gain insight into biological problems at a mechanistic level.
91 skos:inScheme sg:ontologies/subjects/
92 skos:narrower sg:ontologies/subjects/biocatalysis
93 sg:ontologies/subjects/biophysical-chemistry
94 sg:ontologies/subjects/biosynthesis
95 sg:ontologies/subjects/carbohydrates
96 sg:ontologies/subjects/chemical-ecology
97 sg:ontologies/subjects/chemical-genetics
98 sg:ontologies/subjects/chemical-libraries
99 sg:ontologies/subjects/chemical-modification
100 sg:ontologies/subjects/chemical-tools
101 sg:ontologies/subjects/cheminformatics
102 sg:ontologies/subjects/combinatorial-libraries
103 sg:ontologies/subjects/computational-chemistry
104 sg:ontologies/subjects/dna
105 sg:ontologies/subjects/drug-delivery
106 sg:ontologies/subjects/enzyme-mechanisms
107 sg:ontologies/subjects/enzymes
108 sg:ontologies/subjects/glycobiology
109 sg:ontologies/subjects/glycomics
110 sg:ontologies/subjects/ion-channels
111 sg:ontologies/subjects/kinases
112 sg:ontologies/subjects/lipidomics
113 sg:ontologies/subjects/lipids
114 sg:ontologies/subjects/mechanism-of-action
115 sg:ontologies/subjects/membranes
116 sg:ontologies/subjects/metabolic-pathways
117 sg:ontologies/subjects/metabolomics
118 sg:ontologies/subjects/metals
119 sg:ontologies/subjects/natural-products
120 sg:ontologies/subjects/networks-and-systems-biology
121 sg:ontologies/subjects/nucleic-acids
122 sg:ontologies/subjects/peptides
123 sg:ontologies/subjects/pharmacology
124 sg:ontologies/subjects/post-translational-modifications
125 sg:ontologies/subjects/proteases
126 sg:ontologies/subjects/protein-design
127 sg:ontologies/subjects/protein-folding
128 sg:ontologies/subjects/proteins
129 sg:ontologies/subjects/proteomics
130 sg:ontologies/subjects/rna
131 sg:ontologies/subjects/screening
132 sg:ontologies/subjects/small-molecules
133 sg:ontologies/subjects/synthetic-biology
134 sg:ontologies/subjects/target-identification
135 sg:ontologies/subjects/target-validation
136 sg:ontologies/subjects/transporters
137 skos:prefLabel Chemical biology
138 sg:ontologies/subjects/iron sgo:sdDataset onto_subjects
139 rdf:type npg:Subject
140 skos:Concept
141 rdfs:label Iron
142 skos:broader sg:ontologies/subjects/metals
143 skos:definition Iron (Fe, atomic number 26) is a redox-active transition metal element found in living systems as Fe2+ or Fe3+ ions. It is rarely found free in biology, but is bound to proteins such as ferritin or haem, to form metalloproteins such as haemoglobin, which is responsible for the transport of oxygen in the blood.
144 skos:inScheme sg:ontologies/subjects/
145 skos:prefLabel Iron
146 sg:ontologies/subjects/magnesium sgo:sdDataset onto_subjects
147 rdf:type npg:Subject
148 skos:Concept
149 rdfs:label Magnesium
150 skos:broader sg:ontologies/subjects/metals
151 skos:definition Magnesium (Mg, atomic number 12) is an alkaline earth metal that exists in living systems as Mg2+ ions. Various metalloproteins require magnesium for their function and these are involved in glycolysis and nucleic acid biochemistry. Magnesium can be bound directly or indirectly in metalloproteins or directly to ATP for ATP-dependent reactions.
152 skos:inScheme sg:ontologies/subjects/
153 skos:prefLabel Magnesium
154 sg:ontologies/subjects/potassium sgo:sdDataset onto_subjects
155 rdf:type npg:Subject
156 skos:Concept
157 rdfs:label Potassium
158 skos:altLabel K
159 Potassium Ion Level
160 skos:broader sg:ontologies/subjects/metals
161 skos:definition Potassium (K, atomic number 19) is an alkali metal and its ions (K+) are necessary for the function of all living cells. Potassium is important in hyperpolarization of membranes during nerve transmission and in regulating a cell's osmotic balance. Potassium is transported across membranes by potassium channels and the ion pump Na+/K+-ATPase.
162 skos:inScheme sg:ontologies/subjects/
163 skos:prefLabel Potassium
164 sg:ontologies/subjects/sodium sgo:sdDataset onto_subjects
165 rdf:type npg:Subject
166 skos:Concept
167 rdfs:label Sodium
168 skos:altLabel Sodium Ion Level
169 skos:broader sg:ontologies/subjects/metals
170 skos:definition Sodium (Na, atomic number 11) is an alkali metal that exists in living systems as Na+ ions. In physiology, it regulates blood volume, blood pressure, osmotic equilibrium and cellular pH. Sodium is transported though membranes to and from the extracellular fluid via sodium channels and the sodium–potassium pump.
171 skos:inScheme sg:ontologies/subjects/
172 skos:prefLabel Sodium
173 skos:Concept sgo:sdDataset for_codes
174 rdf:type rdfs:Class
175 rdfs:Resource
176 rdfs:subClassOf rdfs:Resource
177 skos:Concept
 




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