Lipids


Ontology type: npg:Subject  | skos:Concept     


Concept Info

NAME

Lipids

DESCRIPTION

Lipids are hydrophobic or amphiphilic small molecules that include sterols, waxes, fatty acids and phospholipids, and are insoluble in water and soluble in organic solvent. Biological lipids are generated from ketoacyl and isoprene (CH2=C(CH3)CH=CH2) groups and include glycerolipids, sphingolipids, fatty acids and polyketides. Lipids play roles in energy storage, signalling and as structural components.

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Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/ontologies/subjects/lipids'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/ontologies/subjects/lipids'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/ontologies/subjects/lipids'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/ontologies/subjects/lipids'


 

This table displays all metadata directly associated to this object as RDF triples.

318 TRIPLES      9 PREDICATES      29 URIs      4 LITERALS

Subject Predicate Object
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112 sg:ontologies/subjects/dna
113 sg:ontologies/subjects/drug-delivery
114 sg:ontologies/subjects/enzyme-mechanisms
115 sg:ontologies/subjects/enzymes
116 sg:ontologies/subjects/glycobiology
117 sg:ontologies/subjects/glycomics
118 sg:ontologies/subjects/ion-channels
119 sg:ontologies/subjects/kinases
120 sg:ontologies/subjects/lipidomics
121 sg:ontologies/subjects/lipids
122 sg:ontologies/subjects/mechanism-of-action
123 sg:ontologies/subjects/membranes
124 sg:ontologies/subjects/metabolic-pathways
125 sg:ontologies/subjects/metabolomics
126 sg:ontologies/subjects/metals
127 sg:ontologies/subjects/natural-products
128 sg:ontologies/subjects/networks-and-systems-biology
129 sg:ontologies/subjects/nucleic-acids
130 sg:ontologies/subjects/peptides
131 sg:ontologies/subjects/pharmacology
132 sg:ontologies/subjects/post-translational-modifications
133 sg:ontologies/subjects/proteases
134 sg:ontologies/subjects/protein-design
135 sg:ontologies/subjects/protein-folding
136 sg:ontologies/subjects/proteins
137 sg:ontologies/subjects/proteomics
138 sg:ontologies/subjects/rna
139 sg:ontologies/subjects/screening
140 sg:ontologies/subjects/small-molecules
141 sg:ontologies/subjects/synthetic-biology
142 sg:ontologies/subjects/target-identification
143 sg:ontologies/subjects/target-validation
144 sg:ontologies/subjects/transporters
145 skos:prefLabel Chemical biology
146 sg:ontologies/subjects/fats sgo:sdDataset onto_subjects
147 rdf:type npg:Subject
148 skos:Concept
149 rdfs:label Fats
150 skos:altLabel Fat
151 Triacylglycerol
152 Triacylglycerols
153 Triglyceride
154 Triglycerides
155 skos:broader sg:ontologies/subjects/lipids
156 skos:definition Fats are lipid small molecules generated by esterification between fatty acids and glycerol to generate a triglyceride. Fats are soluble in organic solvents, but insoluble in water. They can be either solid or liquid, though references to fats generally imply the solid unsaturated forms, containing carbon double bonds, rather than unsaturated forms.
157 skos:inScheme sg:ontologies/subjects/
158 skos:prefLabel Fats
159 sg:ontologies/subjects/fatty-acids sgo:sdDataset onto_subjects
160 rdf:type npg:Subject
161 skos:Concept
162 rdfs:label Fatty acids
163 skos:altLabel Aliphatic Acids
164 Esterified Fatty Acids
165 Fatty acid
166 Saturated Fatty Acids
167 skos:broader sg:ontologies/subjects/lipids
168 skos:definition Fatty acids are organic acids with at least one carboxyl (-C(=O)OH, -COOH or -CO2H) group and a long carbon chain that can be joined by double bonds, as in unsaturated fatty acids, or single bonds, as in saturated fatty acids. Fatty acids are generally derived from triglycerides and phospholipids. Dietary fats are generally fatty acids.
169 skos:inScheme sg:ontologies/subjects/
170 skos:prefLabel Fatty acids
171 sg:ontologies/subjects/fatty-alcohols sgo:sdDataset onto_subjects
172 rdf:type npg:Subject
173 skos:Concept
174 rdfs:label Fatty alcohols
175 skos:altLabel Fatty alcohol
176 skos:broader sg:ontologies/subjects/lipids
177 skos:definition Fatty alcohols are lipid small molecules that consist of a terminal hydroxyl (OH) group and a long carbon chain. They are the reduced forms of fatty acids in which the carboxylic acid has been reduced to give a primary alcohol. They are derived from natural fats and oils and can sometimes be unsaturated or branched.
178 skos:inScheme sg:ontologies/subjects/
179 skos:prefLabel Fatty alcohols
180 sg:ontologies/subjects/glycerides sgo:sdDataset onto_subjects
181 rdf:type npg:Subject
182 skos:Concept
183 rdfs:label Glycerides
184 skos:altLabel Acylglycerol
185 Acylglycerols
186 skos:broader sg:ontologies/subjects/lipids
187 skos:definition Glycerides are generated when glycerol is modified at one (monoglycerides), two (diglycerides) or all three (triglycerides or fats) of its hydroxyl (OH) functional groups by esterification with a fatty acid.
188 skos:inScheme sg:ontologies/subjects/
189 skos:prefLabel Glycerides
190 sg:ontologies/subjects/glycolipids sgo:sdDataset onto_subjects
191 rdf:type npg:Subject
192 skos:Concept
193 rdfs:label Glycolipids
194 skos:broader sg:ontologies/subjects/lipids
195 skos:definition Glycolipids are glycoconjugates of lipids that are generally found on the extracellular face of eukaryotic cellular membranes, and function to maintain stability of the membrane and to facilitate cell–cell interactions. Glycolipids can also act as receptors for viruses and other pathogens to enter cells. Gangliosides and cerebrosides that form glycosphingolipids (carbohydrate + sphingolipid) are two classes of glycolipids.
196 skos:inScheme sg:ontologies/subjects/
197 skos:prefLabel Glycolipids
198 sg:ontologies/subjects/lipid-peroxides sgo:sdDataset onto_subjects
199 rdf:type npg:Subject
200 skos:Concept
201 rdfs:label Lipid peroxides
202 skos:altLabel Fatty Acid Hydroperoxides
203 Lipid Hydroperoxide
204 Lipoperoxides
205 skos:broader sg:ontologies/subjects/lipids
206 skos:definition Lipid peroxides are oxidative degradation products of lipids, generated by a free radical chain reaction. Because of their abundance of reactive hydrogens, polyunsaturated fatty acids are highly susceptible to lipid peroxidation, which compromises the integrity and function of the cell membrane in which they reside.
207 skos:inScheme sg:ontologies/subjects/
208 skos:prefLabel Lipid peroxides
209 sg:ontologies/subjects/lipofuscin sgo:sdDataset onto_subjects
210 rdf:type npg:Subject
211 skos:Concept
212 rdfs:label Lipofuscin
213 skos:broader sg:ontologies/subjects/lipids
214 skos:definition Lipofuscin is similar to ceroid and is a type of lipochrome (deposit of lipid-rich pigment) that appears in histological examination of tissues, especially from older organisms and particularly from the eye where it can indicate macular degeneration. Lipofuscin is thought to be a product of oxidation of unsaturated fatty acids and is correlated with membrane damage.
215 skos:inScheme sg:ontologies/subjects/
216 skos:prefLabel Lipofuscin
217 sg:ontologies/subjects/lipopeptides sgo:sdDataset onto_subjects
218 rdf:type npg:Subject
219 skos:Concept
220 rdfs:label Lipopeptides
221 skos:altLabel Anionic Lipopeptide
222 Anionic Lipopeptides
223 Cationic Lipopeptide
224 Cationic Lipopeptides
225 skos:broader sg:ontologies/subjects/lipids
226 skos:definition Lipopeptides are peptides modified covalently by at least one lipid molecule. Lipopeptides expressed on the surface of bacterial cells can act as pathogen-associated molecular patterns that are recognized by the host immune system. They may also be used as antibiotics.
227 skos:inScheme sg:ontologies/subjects/
228 skos:prefLabel Lipopeptides
229 sg:ontologies/subjects/lipopolysaccharides sgo:sdDataset onto_subjects
230 rdf:type npg:Subject
231 skos:Concept
232 rdfs:label Lipopolysaccharides
233 skos:altLabel Lipoglycans
234 skos:broader sg:ontologies/subjects/lipids
235 skos:definition Lipopolysaccharides are lipids that are covalently modified with polysaccharides, consisting generally of three parts: a repetitive glycan polymer (an O-lipid), the polysaccharide component and Lipid A (two glucosamine groups with attached fatty acids), and often containing one phosphate on each glucosamine. Lipopolysaccharides function in Gram-negative bacterial membranes and are endotoxins released by bacterial lysis.
236 skos:inScheme sg:ontologies/subjects/
237 skos:prefLabel Lipopolysaccharides
238 sg:ontologies/subjects/lipoproteins sgo:sdDataset onto_subjects
239 rdf:type npg:Subject
240 skos:Concept
241 rdfs:label Lipoproteins
242 skos:altLabel Circulating Lipoproteins
243 Lipoprotein
244 skos:broader sg:ontologies/subjects/lipids
245 sg:ontologies/subjects/proteins
246 skos:definition Lipoproteins are large spherical complexes that consist of lipids and proteins. The hydrophobic core consists of triglycerides and a hydrophobic form of cholesterol (cholesteryl esters) is surrounded by a hydrophilic monolayer of free cholesterol, phospholipids and apoproteins. Lipoproteins function in transporting lipids contained within through the bloodstream.
247 skos:inScheme sg:ontologies/subjects/
248 skos:prefLabel Lipoproteins
249 sg:ontologies/subjects/membrane-lipids sgo:sdDataset onto_subjects
250 rdf:type npg:Subject
251 skos:Concept
252 rdfs:label Membrane lipids
253 skos:altLabel Cell Membrane Lipids
254 skos:broader sg:ontologies/subjects/lipids
255 skos:definition Membrane lipids are lipids involved in forming the structure of biological membranes – both the cell membrane and intracellular membranes – and in membrane function, namely compartmentalization of biological processes. Membrane lipids consist primarily of phospholipids, glycolipids and cholesterol, which can be arranged in bilayers and organized with integral and peripheral membrane proteins to generate functioning membranes.
256 skos:inScheme sg:ontologies/subjects/
257 skos:prefLabel Membrane lipids
258 sg:ontologies/subjects/oils sgo:sdDataset onto_subjects
259 rdf:type npg:Subject
260 skos:Concept
261 rdfs:label Oils
262 skos:broader sg:ontologies/subjects/lipids
263 skos:definition Oils in biological systems are lipids that are in liquid form at room temperature. Usually triglycerides, oils are made from glycerol and fatty acids.
264 skos:inScheme sg:ontologies/subjects/
265 skos:prefLabel Oils
266 sg:ontologies/subjects/phospholipids sgo:sdDataset onto_subjects
267 rdf:type npg:Subject
268 skos:Concept
269 rdfs:label Phospholipids
270 skos:altLabel Phosphatides
271 skos:broader sg:ontologies/subjects/lipids
272 skos:definition Phospholipids are lipids that generally consisting of three components: a diglyceride, a phosphate group and another organic molecule for instances choline to create phosphatidylcholine. Phospholipids are a major component of all cellular membranes and can form bilayers.
273 skos:inScheme sg:ontologies/subjects/
274 skos:prefLabel Phospholipids
275 sg:ontologies/subjects/polyhydroxyalkanoates sgo:sdDataset onto_subjects
276 rdf:type npg:Subject
277 skos:Concept
278 rdfs:label Polyhydroxyalkanoates
279 skos:broader sg:ontologies/subjects/lipids
280 skos:definition Polyhydroxyalkanoates are linear polyesters generated by fermentation of sugars or lipids. They are generally made and used by bacteria to store energy and commercially to make bioplastics. Formation of polyhydroxyalkanoates from hydroxy fatty acids of short (3–5 carbons) or medium (6–14 carbons) chain length is catalysed by the polyhydroxyalkanoate (PHA) synthase enzymes.
281 skos:inScheme sg:ontologies/subjects/
282 skos:prefLabel Polyhydroxyalkanoates
283 sg:ontologies/subjects/sphingolipids sgo:sdDataset onto_subjects
284 rdf:type npg:Subject
285 skos:Concept
286 rdfs:label Sphingolipids
287 skos:altLabel Lysosphingolipids
288 skos:broader sg:ontologies/subjects/lipids
289 skos:definition Sphingolipids are lipids with a sphingoid base backbone, bearing its own hydrocarbon chain, an amine group and two hydroxyl groups. The amine group is bonded to a fatty acid of varying length and one of the hydroxyl groups may be functionalized to a phosphate or carbohydrate. Sphingolipids are involved in signal transduction across membranes.
290 skos:inScheme sg:ontologies/subjects/
291 skos:prefLabel Sphingolipids
292 sg:ontologies/subjects/sterols sgo:sdDataset onto_subjects
293 rdf:type npg:Subject
294 skos:Concept
295 rdfs:label Sterols
296 skos:altLabel Steroid alcohol
297 Steroid alcohols
298 Sterol
299 Sterol alcohol
300 Sterol lipid
301 Sterol lipids
302 skos:broader sg:ontologies/subjects/lipids
303 skos:definition Sterols are amphipathic lipids based on the steroid ring structure but with a polar hydroxyl (OH group) on one of the 6-membered rings. Sterols are also known as steroid alcohols, an example of which is cholesterol. They are generated in living systems from acetyl-coA by the HMG-CoA reductase pathway.
304 skos:inScheme sg:ontologies/subjects/
305 skos:prefLabel Sterols
306 sg:ontologies/subjects/waxes sgo:sdDataset onto_subjects
307 rdf:type npg:Subject
308 skos:Concept
309 rdfs:label Waxes
310 skos:broader sg:ontologies/subjects/lipids
311 skos:definition Waxes are lipids composed of esters between fatty acids and fatty alcohols. Waxes are water-insoluble, but soluble in organic, non-polar solvents. Waxes can be found in biological systems, for instance as beeswax and as epicuticular waxes in plants. Biological waxes are generally mixtures so are softer and melt more readily than the pure components.
312 skos:inScheme sg:ontologies/subjects/
313 skos:prefLabel Waxes
314 skos:Concept sgo:sdDataset for_codes
315 rdf:type rdfs:Class
316 rdfs:Resource
317 rdfs:subClassOf rdfs:Resource
318 skos:Concept
 




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